Investigation of neuromodulation of the endbulb of Held synapse in the cochlear nucleus by serotonin and norepinephrine by Maria Groshkova, Maria Groshkova, Maria Groshkova, Maria Groshkova, Maria Groshkova, Theocharis Alvanos, Theocharis Alvanos, Theocharis Alvanos, Yumeng Qi, Fangfang Wang, Carolin Wichmann, Carolin Wichmann, Carolin Wichmann, Carolin Wichmann, Yunfeng Hua, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser

“…Patch-clamp recordings from BCs revealed an increase in frequency of miniature excitatory postsynaptic currents (mEPSCs) upon application of NE but not 5-HT. …”
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Using machine learning algorithms to predict colorectal polyps by Xingjian Xiao, Shiyou Liu, Kubra Maqsood, Xiaohan Yi, Guoqun Xie, Hailei Zhao, Bo Sun, Jianying Mao, Xianglong Xu

“…We propose a machine learning approach that can identify individuals with colorectal polyps in this group, thereby increasing the screening rate for colorectal cancer and helping to prevent the disease. …”
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INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW) by L.V. Smaglyuk, H.V. Voronkova, A.Ye. Karasiunok, A.V. Liakhovska, V.I. Smaglyuk

“…Over the last decade, there has been a clear trend towards an increase in the prevalence of malocclusion, which reaches 80% according to current scientific literature and sometimes it exceeds this percentage. …”
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Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…Year on year, there continue to be unprecedented numbers of consultations in primary care; between 20% and 30% are related to MSKDs. Given the increasing demand for general practitioner (GP) services and current difficulties surrounding GP recruitment and retention, alternative implementable and affordable models of care are essential. …”
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Ductus Venosus Agenesis in Monochorionic Twin Pregnancies Complicated by Fetal Growth Restriction: When to Deliver? by Eleonora Torcia, Alessandra Familiari, Elvira Passananti, Giulia di Marco, Federica Romanzi, Mariarita Trapani, Daniela Visconti, Antonio Lanzone, Elisa Bevilacqua

“…Fetuses with ADV are at increased risk for congenital cardiac disease, heart failure, and fetal growth restriction (FGR). …”
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Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…IntroductionMetabolic-associated fatty liver disease (MAFLD) has emerged as a global health crisis, which is characterized by hepatic lipid accumulation, inflammation, and fibrosis. Currently, effective therapeutic strategies for MAFLD are still scarce.MethodsThis study aimed to explore the hepatoprotective effects and underlying mechanisms of total flavones from Abelmoschus manihot (L.) …”
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Prevalence and associated factors of mammography uptake among the women aged 45 years and above: policy implications from the longitudinal ageing study in India wave I survey by Priyanka Sharma, Dipak Das, Divya Khanna, Atul Budukh, Anita Khokhar, Satyajit Pradhan, Ajay Kumar Khanna, Pankaj Chaturvedi, Rajendra Badwe

“…Among women in 45–59 years age group, secondary or higher education, being currently in union, having diabetes, neurological illness, hearing problems, and reproductive health problems, better cognition level, and self-history of cancer were found to be associated with increased mammography uptake. …”
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Neutralizing Antibody Spectrum in COVID-19 Patients who Became Ill During the Circulation of Different SARS-CoV-2 Variants by S. K. Pylaeva, L. I. Kozlovskaya, A. A. Erovichenkov, D. I. Sirazova, E. Y. Shustova, E. A. Artamonova, A. A. Sinyugina, I. V. Gordeychuk, D. V. Troshyanskiy, E. V. Kosareva, O. N. Solodovnikova, R. K. Kogotyzhev, A. U. Berestovskaia, I. N. Tyurin, D. N. Protsenko, A. A. Ishmukhametov

“…Thus, a fraction of people, regardless of age, who became infected in 2020-2021 have an antibody spectrum capable of neutralizing current and possibly related SARS-CoV-2 variants that will emerge in the near future. …”
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Assessing Farmers’ Prefrences in using Water Resources in Varamin Plain, Iran A Discrete Choice Experiment Technique by Hojatolah Shayeganfard, Mohsen Mehrara

“…In addition to that, in the context of providing policy recommendations, it is suggested to pay serious attention to the issue of agricultural water in the Varamin Plain. …”
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Anticancer Potential, Phenolic Profile, and Antioxidant Properties of <i>Synsepalum dulcificum</i> (Miracle Berry) in Colorectal Tumor Cell Lines by Josefa Quiroz-Troncoso, Nicolás Alegría-Aravena, Blanca Sáenz de Mierae, Marta Sánchez-Díez, Raquel González-Martos, Clara E. Gavira-O’Neill, Emilio J. González, Maria González-Miquel, Cristian Valdés Vergara, Gloria González-Silva, Loan Bensadon-Naeder, Javier Galeano, Carmen Ramírez-Castillejo

“…Polyphenols, recognized for their antioxidant capacity, have shown potential in improving the response treatment of various diseases, including cancer. In this context, polyphenols have the ability to induce cytotoxicity in tumor cells, making them possible complementary agents to current treatments. …”
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Potential Herb-Drug Interactions Among Elderly Nursing Home Residents in Romania by Hanna Sebesi, László István Bába, Melinda Kolcsár, Zsolt Gáll, Soma Dávid

“…Evidence shows that herb-drug interactions (HDIs) are significant in clinical pharmacology. However, the current use of herbal supplements and the prevalence of HDIs among elderly patients in nursing homes is not known. …”
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Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock by Qiuyu Gao, Qiao Feng, Dong Zhou, Zhili Ding, Changle Qi, Youqin Kong, Qiyou Xu

“…The current study was designed to explore the effects of dietary vitamin E on the ovarian development and health of female largemouth bass (Micropterus salmoides). …”
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The Validity of Cryptocurrency Transactions and the Analysis of Associated Disputes by Hossein Qahari, Javad Hosseinzadeh

“…Introduction The complex economic relations in the current era increasingly demand the provision of efficient, rational, and comprehensive legal norms. …”
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Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy by Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini

“…The obtained results suggest that other transport proteins participate in Ca2+ homeostasis in FD and their dysfunction may be directly involved in nociception. In this context, plasma-membrane Ca2+ ATPases exhibited reduced activity in FD, leading to an increased resting [Ca2+]i in sensory neurons. …”
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A quantitative assessment of the behavior of metallic elements in urban soils exposed to industrial dusts near Dunkerque (northern France) by M. Casetta, S. Philippe, L. Courcot, D. Dumoulin, G. Billon, F. Baudin, F. Henry, M. Hermoso, J. Caillaud

“…In this context, the monitoring of industrial PTEs in these urban soils is highly recommended, considering (1) the presence of allotment gardens in the vicinity of emitters and (2) the potential evolution of soil conditions due to increasing flood events.…”
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Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway by Seo Yeon Kim, Seo Yeon Kim, Jung-Ho Yoon, Da Hyun Jung, Ga Hee Kim, Chul Hoon Kim, Chul Hoon Kim, Sang Kil Lee

“…Esomeprazole, a representative PPI, and three currently marketed P-CABs (vonoprazan, tegoprazan, and fexuprazan) were used for pretreatment. …”
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Artificial Intelligent Model to Enhance Thermal Conductivity of TiO₂-Al₂O₃/Water-Ethylene Glycol-Based Hybrid Nanofluid for Automotive Radiator by Md. Munirul Hasan, Md. Mustafizur Rahman, Md. Arafatur Rahman, Suraya Abu Bakar, Mohammad Saiful Islam, Tarek Khalifa

“…Vehicular cooling system is one of the priorities for the automobile industry, aiming to achieve sustainability and energy efficiency. Currently, coolants are being utilized in cooling systems that exhibit super heat transfer capabilities. …”
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Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China by Fei Zhang, Yao Yang, Na Liang, Huayue Liang, Yongzheng Chen, Zhaosen Lin, Tongbi Chen, Wenling Tan, Yuan Yang, Rongye Huang, Lin Yao, Fuling Chen, Xingzhen Huang, Li Ye, Hao Liang, Bingyu Liang

“…In China, the number of newly reported HIV infections in older people is increasing rapidly. However, clear information on the impact of older people on HIV transmission is limited. …”
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Trends and Prospects in Educational Modernisation: A Hermeneutic Approach by A. F. Zakirova, Ye. N. Volodina

“…To overcome this situation and to break this deadlock, a profound reconsideration of the values underlying mechanisms of reform is required, taking into account multifaceted personal, social, national and universal relations, as well as unity of content, forms and means of education.The aims of the research were identified as follows: to analyse the current trends of modernisation in comprehensive schools and higher educational establishments; to justify humanistic mechanisms for improving the modernisation in the context of language education, which performs personally developing and socialising functions under ideological pluralism and opposition of value systems.Methodology and research methods. …”
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Integrated meta-analysis and network pharmacology analysis: evaluation of Zhigancao decoction as treatment for diabetic cardiomyopathy by Kangshou Ji, Kangshou Ji, Meizi Han, Mingqian Yang, Qian Xu, Yan Zhang, Yan Zhang

“…Additionally, the utilization of ZGCD was leading to a reduction in LVEDV, LVESV and LVDD, also a greater increase in LVEF. Meanwhile, the utilization of ZGCD during intervention was more effective in reducing SBP, and DBP. …”
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