Topical Application of RNAi Therapy Using Surface-Modified Liposomes for Treating Retinal-Vein Occlusion by Taishi Shiratori, Takaaki Ito, Anri Nishinaka, Ryosuke Matsumiya, Eriko Yamazoe, Hirofumi Takeuchi, Hideaki Hara, Kohei Tahara

“…Recently, antibody- and nucleic acid-based pharmaceuticals have increasingly been used to treat retinal diseases, with improvement or cure as the goal; however, these drugs are currently only administered by intravitreal injection. …”
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Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial by Shoko Kondo, MD, Yoshiko Okano, MD, PhD, Satoshi Iraha, MD, PhD, Shoji Tokunaga, PhD

“…Although leprosy is bacteriologically curable, there is currently no efficient treatment. Eye drops containing tetrapeptides, phenylalanine-glycine-leucine-methionine-amide (FGLM-NH2) and serine-serine-serine-arginine (SSSR), derived from substance P and insulin-like growth factor 1, are clinically efficacious in the treatment of corneal epithelial disorders caused by neurotrophic keratopathy. …”
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A methionine/aspartate-rich synthetic peptide delineated from N-terminal region of nucleophosmin protein effectively protects against cadmium-induced toxicity by Rui Yan, Heng Wee Tan, Xiao-Yun Zhao, Jia-Yi Wu, Qiu-Hua Zhong, Xiu-Yun Wang, Na-Li Cai, Yan-Ming Xu, Andy T.Y. Lau

“…The molecular mechanism of Cd cytotoxicity is complicated and still not well understood, and treatment options for Cd cytotoxicity are lacking. Currently, only a limited number of Cd-targeted proteins have been identified. …”
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Identifying studies evaluating susceptibility factors for chemical health assessments: A case study focused on methylmercury developmental neurotoxicity by Deborah Segal, Rebecca Nachman, Onyemaechi Nweke, Elizabeth Radke, Geanine Brunson, Bita Khoshhal, G. Nicole Helguero, Leonid Kopylev

“…However, at this time, Approach 1, involving the application of a dose–response filter, is currently recommended for identifying epidemiology papers with information on susceptibility factors.…”
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Analysis of Outdoor and Indoor Radon Concentration Time Series Recorded with RadonEye Monitors by Peter Bossew, Eleonora Benà, Scott Chambers, Miroslaw Janik

“…Consumer-grade economical radon monitors are becoming increasingly popular in private and institutional use, in the contexts of both Citizen Science and traditional research. …”
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Energy-driven circular design in the built environment: rethinking architecture and infrastructure by Williams Chibueze Munonye, George Oche Ajonye

“…This study explores the integration of energy-driven circular design principles within the built environment, aiming to foster sustainable, low-carbon cities and buildings. Currently as urbanization accelerates and environmental concerns heighten, the need for circular economy practices that promote energy efficiency, resource optimization, and waste reduction becomes increasingly urgent. …”
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Curious Travellers: New Journeys for the Home Tour by Mary-Ann Constantine

“…The creation of new editions continues to generate new topics and research questions, including Anglophone/Celtic-language interactions; the writings of women tourists; the role of material objects (specimens and souvenirs) and of visual culture in knowledge exchange and production. Increasingly, project researchers are relating their work to broader global contexts of colonialism and environmental history. …”
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Computational methods for protein identification from mass spectrometry data. by Leo McHugh, Jonathan W Arthur

“…Here, we undertake a systematic review of the currently available methods and algorithms for interpreting, managing, and analyzing biological data associated with protein identification. …”
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Trends of compressive word formation in modern Russian language by Natalia A. Nikolina

“…The increasing frequency of contaminated formations in modern Russian speech is revealed. …”
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Military and political security in the Arctic before and amidst the Ukrainian crisis by I. A. Arzhanov

“…This course has been reflected in a whole series of alliance’s military exercises, which, as shown in the article, are becoming increasingly extensive and regular year by year. The author concludes that the Ukrainian crisis has only laid bare the true aspirations of the NATO countries seeking to contain Russia in the Far North and refusing to consider its interests and build a constructive dialogue in the field of military and political security. …”
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UML/OCL based design and the transition towards temporal object relational database with bitemporal data by Soumiya Ain El Hayat, Fouad Toufik, Mohamed Bahaj

“…In software modeling, UML (Unified modeling language) receives increasing attention from designers of real-time systems in software development. …”
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Melt‐Processable and Electrospinnable Shape‐Memory Hydrogels by Turdimuhammad Abdullah, Cagatay Altınkok, Oguz Okay

“…Abstract Due to their ability to adapt to subtle changes in response to various external and internal stimuli, smart hydrogels have become increasingly popular in research and industry. However, many currently available hydrogels suffer from poor processability and inferior mechanical properties. …”
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Effects of Dynamic Agrivoltaics on Containerized Raspberry Plants: Results of the First Season by Perrine Juillion, Candice Tranchant, Kaoutar Nadi, Jimmy Noel, Benoit Valle, Jérôme Chopard, Gerardo Lopez, Camille Crevat, Xavier Bunker, Damien Fumey

“…The protection from the DAV reduced mean air temperature by 1.8°C and increased mean relative humidity by 7.3% in comparison to the CTL. …”
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Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. by Sharon E Robertson, Maya Yasukawa, Douglas C Marchion, Yin Xiong, Syeda Mahrukh Hussnain Naqvi, Tarik Gheit, Massimo Tommasino, Robert M Wenham, Anna R Giuliano, Johnathan M Lancaster, Mian M K Shahzad

“…<h4>Introduction</h4>Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.…”
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Mapping the global distribution and conservation status of oases—ecosystems of pivotal biocultural relevance by Juan Antonio Hernández-Agüero, Mechthilde Falkenhahn, Jessica Hetzer, Karsten Wesche, Christiane Zarfl, Klement Tockner

“…However, less than 0.5% of their total area is currently under protection, making oases one of the least conserved ecosystems worldwide. …”
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A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen by Michael N Dawson, Jan C. Axmacher, Carl Beierkuhnlein, Jessica L. Blois, Bethany A. Bradley, Anna F. Cord, Jürgen Dengler, Kate S. He, Lawrence R. Heaney, Roland Jansson, Miguel D. Mahecha, Corinne Myers, David Nogués-Bravo, Anna Papadopoulou, Björn Reu, Francisco Rodríguez-Sánchez, Manuel J. Steinbauer, Alycia Stigall, Mao-Ning Tuanmu, Daniel G. Gavin

“…., advances in genetics, remote sensing, modeling) that promote studies with increasing detail and at increasing scales; disciplinary breadth is being diversified (e.g., by developments in paleobiogeography and microbiology) and integrated through the transfer of approaches and sharing of theory (e.g., spatial modeling and phylogenetics in evolutionary–ecological contexts). …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. …”
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Prompt closure versus gradual weaning of extraventricular drainage for hydrocephalus in adult patients with aneurysmal subarachnoid haemorrhage: a systematic review protocol with m... by Jørn Wetterslev, Tenna Capion, Alexander Lilja-Cyron, Marianne Juhler, Tiit Illimar Mathiesen

“…Sparse data exist on the recommendation of cessation strategy and patients are currently being treated on the basis of personal experience and expert opinion. …”
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Prioritization of potential drug targets for diabetic kidney disease using integrative omics data mining and causal inference by Junyu Zhang, Jie Peng, Chaolun Yu, Yu Ning, Wenhui Lin, Mingxing Ni, Qiang Xie, Chuan Yang, Huiying Liang, Miao Lin

“…Diabetic kidney disease (DKD) with increasing global prevalence lacks effective therapeutic targets to halt or reverse its progression. …”
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Letter to readers by Francesca Gorini

“…The evolution of educational technologies and their impact on the educational system is, also, a topic that personally involves me, having dedicated part of my research job in exploring which skills are essential to preserve and develop in order to interact appropriately with AI – a tool which is becoming increasingly pervasive even in teaching and educational contexts. …”
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