Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway by Seo Yeon Kim, Seo Yeon Kim, Jung-Ho Yoon, Da Hyun Jung, Ga Hee Kim, Chul Hoon Kim, Chul Hoon Kim, Sang Kil Lee

“…Esomeprazole, a representative PPI, and three currently marketed P-CABs (vonoprazan, tegoprazan, and fexuprazan) were used for pretreatment. …”
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Artificial Intelligent Model to Enhance Thermal Conductivity of TiO₂-Al₂O₃/Water-Ethylene Glycol-Based Hybrid Nanofluid for Automotive Radiator by Md. Munirul Hasan, Md. Mustafizur Rahman, Md. Arafatur Rahman, Suraya Abu Bakar, Mohammad Saiful Islam, Tarek Khalifa

“…Vehicular cooling system is one of the priorities for the automobile industry, aiming to achieve sustainability and energy efficiency. Currently, coolants are being utilized in cooling systems that exhibit super heat transfer capabilities. …”
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Transmission network and phylogenetic analysis reveal older male-centered transmission of CRF01_AE and CRF07_BC in Guangxi, China by Fei Zhang, Yao Yang, Na Liang, Huayue Liang, Yongzheng Chen, Zhaosen Lin, Tongbi Chen, Wenling Tan, Yuan Yang, Rongye Huang, Lin Yao, Fuling Chen, Xingzhen Huang, Li Ye, Hao Liang, Bingyu Liang

“…In China, the number of newly reported HIV infections in older people is increasing rapidly. However, clear information on the impact of older people on HIV transmission is limited. …”
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Multi-method evaluation of volatile flavor compounds in five kiwifruit varieties by ZENG Shuo, GUO Xinyu, NIU Dongsheng, LI Feng

“…[Objective] Fruit wine, as a food of fruit processing, not only enhances the flavor diversity of kiwifruit but also increases its biological activity, leading to the production of kiwifruit wine with a unique flavor, combined fruit with wine aromas, and rich nutrition. …”
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A Framework for Cervical Cancer Elimination in Low-and-Middle-Income Countries: A Scoping Review and Roadmap for Interventions and Research Priorities by Michelle B. Shin, Gui Liu, Nelly Mugo, Nelly Mugo, Patricia J. Garcia, Patricia J. Garcia, Darcy W. Rao, Darcy W. Rao, Cara J. Broshkevitch, Linda O. Eckert, Linda O. Eckert, Leeya F. Pinder, Leeya F. Pinder, Judith N. Wasserheit, Judith N. Wasserheit, Judith N. Wasserheit, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas

“…Using these data, we developed a logic model to summarize the current state of science and identified evidence gaps and priority research questions for each prevention strategy. …”
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Characterizing obesity: A qualitative study by Tim Bober, Flor Cameron, Lane Alexander, J.G. Luiggi-Hernandez, David Rometo, Linda-Marie Lavenburg, Haley Grant, Emily Klawson, Autumn R. Boyer, Kathleen M. McTigue, Julie Gouveia-Pisano, Avani Patel, Lisa Tarasenko, Jannette Escobar, Allison Brenner, Scott M. Vouri, Feng Dai, Megan E. Hamm

“…Conclusion: This qualitative study of people with obesity, health professionals, and payors demonstrated current views of addressing and treating obesity in clinical settings. …”
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Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70 by Lei Zhang, Jianyi Gao, Tianyan Chen, Xiang Chen, Xianyan Ji, Kai Ye, Jiahong Yu, Bin Tang, Yusheng Wei, Hong Xu, Jiabo Hu

“…Additionally, hESC-NSC-derived MVs contained high levels of heat shock protein 70 (HSP-70), which can increase the level of HSP-70 in cells. …”
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In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives by Héverton Mendes Araújo, Gabriel Acácio de Moura, Yasmim Mendes Rocha, Cristian Vicson Pinheiro Gomes, Valentina Nascimento e Melo de Oliveira, Ronaldo Nascimento de Oliveira, Larissa Deadame de Figueiredo Nicolete, Emanuel Paula Magalhães, Ramon R.P.P.B. de Menezes, Roberto Nicolete

“…Exposure to melanoma murine supernatants also promotes M1 polarization. Supernatants containing traces of 1,2,4-oxadiazole derivative 2 (Supernatants B, C, and D) increased the percentage of M1 cells compared to Supernatant A, as well as elevated levels of nitrite, TNF-α, and IL-12. 1,2,4-oxadiazole derivative 2 combined with Supernatant A and 1,2,4-oxadiazole derivative 2 combined with LPS also resulted in higher M1 polarization, suggesting a synergistic effect on M1 polarization and TNF-α production. …”
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PANCAKE: A Python-based Numerical Color–Magnitude Diagram Analysis Package by Yun Zheng, Yujiao Yang, Yong-Kun Zhang, Zheng Zheng, Jing Wang, Lister Staveley-Smith, Chao-Wei Tsai, Di Li, Chao Liu, Jingjing Hu, Huaxi Chen, Donghui Quan, Yinghui Zheng, Hangyuan Li

“…The color–magnitude diagram (CMD) stands out as the most accurate tool currently available for inferring the star formation histories (SFHs) of nearby galaxies with stellar-resolved multiband data. …”
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Dealing with Complexity – Knowledge, design, and management of the built environment by Cesare Sposito, Francesca Scalisi

“…How do we place knowledge and learning into a system to better understand the current era’s multidimensional, fundamental, and global issues in their irreducible complexity? …”
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Comparative chromium adsorptive capacity of different low-cost materials using fixed bed column by Asma Shakeel, Inayat Mustafa Khan, Faheem Jeelani, Mukhtar Iderawumi Abdulraheem, Salma Imam Sulaiman, Mohmad Auyoub Bhat, Javid Ahmad Bhat, Tahir Sheikh, Rakshanda Anayat, Syed Andleeba Jan, Mehnaz Shakeel, Mohd. Tariq, Arifullah Mohammed, Tabarak Malik

“…Abstract The accessibility of pure water is crucial for various human activities and is increasingly in demand due to the growing global population. …”
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Application of dry electrodes in supercapacitors and lithium-ion batteries by Guolei ZHANG, Keliang ZHANG, Yabin AN, Chen LI, Guanwei LIU, Xianzhong SUN, Changzhou YUAN, Kai WANG, Xiong ZHANG, Yanwei MA

“…Finally, the challenges and issues in the current use of dry electrodes in supercapacitors and lithium-ion batteries are summarized, along with proposed future directions. …”
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Exploring Scientific Outputs about Globalization: A Conceptual Framework Study by Saleh Rahimi, Faramarz Soheili

“…The extracted data spanned 25 years (1999–2023) and included 1,281 documents containing 4,502 author keywords. After standardization, 2,169 unique keywords remained. …”
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Рreventive efficacy of interferon -2b in the COVID-19 pandemic by Zh. B. Ponezheva, A. A. Grishaeva, I. V. Mannanova, A. N. Kupchenko, S. B. Yatsyshina, S. V. Krasnova, V. V. Malynovskaya, V. G. Akimkin

“…The amount of infected people has already exceeded 48 million, and more than 1 million deaths have been registered. A steady increase of new cases of COVID-19 is currently observed on the territory of the Russian Federation. …”
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Solid waste management service chain and sanitation safety: a case study of existing practice in Addis Ababa, Ethiopia by Shegaw Fentaye Sisay, Sirak Robele Gari, Sirak Robele Gari, Argaw Ambelu

“…Additionally, 85% of households used storage and transport containers that had leaks, potentially leading to contamination and infection. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
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HIV-1 suppression and rare dolutegravir resistance in antiretroviral-experienced people with HIV in Liberia by James Soka Moses, Alice K. Pau, Safia Kuriakose, Greg Grandits, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Lisheng Dai, Muhammad A. Khan, Helene Highbarger, Moses Mannah, Johnathan McCullough, Carla Chorley, Isaac Morlu, Joseph Dorbor, Ophelia Talweh Bongolee, Rebecca Slewion, Esther Akpa, Barthalomew Wilson, April L. Poole, Stacy L. Kopka, Tracey Miller, Cecelia J. Nuta, Christina Lindan, David Glidden, Jeffrey N. Martin, Kumblytee L. Johnson, Robin L. Dewar, Ian Wachekwa, Stephen A. Migueles

“…Abstract Background Increasingly, persons with HIV in Liberia are receiving antiretroviral therapy containing the integrase strand-transfer inhibitor (InSTI) dolutegravir (DTG), but the prevalence of and factors associated with virologic failure and HIV drug resistance (HIVDR) remain unknown. …”
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Isolation and characterization of novel bioactive peptides from legume seed wastes and their application as eco-friendly coating improve the physicochemical, microbiological, aroma... by Samir A. Mahgoub, Hayfa Habes Almutairi, Nourhan H.I. Abd-El Fattah, Ashraf S. El-Sayed, Merfat O. Aljhdli, Salah A. Khalifa, Ahmed M. Saad, Layla A. Almutairi, Mohammed A. Alqahtani, Eman A. Beyari, Wafaa Ahmed Alhazmi, Nahed A. El-Wafai, Khaled A. El-Tarabily, Mohamed T. El-Saadony

“…Valorizing food waste into bioactive compounds is a growing global trend. The current study aimed to evaluate the physicochemical, functional, and bioactive properties of chickpea seed waste peptides (CWP) and pea seed waste peptides (PWP) and assess their potential in enhancing probiotic-enriched Ras cheese. …”
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Mortality impact, risks, and benefits of general population screening for ovarian cancer: the UKCTOCS randomised controlled trial by Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Andy Ryan, Jatinderpal K Kalsi, Naveena Singh, Anne Dawnay, Lesley Fallowfield, Alistair J McGuire, Stuart Campbell, Steven J Skates, Mahesh Parmar, Ian J Jacobs

“…While screening did not increase anxiety, there was slightly increased worry in women who were asked to return for more intense repeat testing. …”
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