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1861
Application of biomedical cell products in the treatment of congenital epidermolysis bullosa
Published 2024-11-01“…Congenital epidermolysis bullosa is a phenotypically and genetically heterogeneous group of genodermatoses, which are characterized by decreasing of skin’s structural protein production up to complete absence or violation of the structure as a result of mutation. …”
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1862
Occurrence and distribution of citrus tatter leaf disease in Zhejiang and genetic diversity analysis of its pathogen
Published 2025-06-01“…[Objective] Citrus tatter leaf disease is a viral disease that harms citrus trees. Currently, it is showing an increasing trend of spreading and causing plant weakness, death, and even large-scale destruction of orchards. …”
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1863
Effect of partial substitution of wheat flour (Triticum spp) with vetch flour (Vicia sativa) on the technological and sensory properties of bread
Published 2025-12-01“…Vicia sativa (common vetch) seeds contain valuable nutrients but are currently unsafe for human consumption. …”
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1864
Study of nicotine content in the aerosols of ENDS of various designs
Published 2021-04-01“…Currently, a unified approach to the regulation of NCP and control of the content of toxic substances in the aerosol has not been developed, which leads to the use of various modes of aerosol collection on laboratory smoking machines. …”
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1865
<i>MAGE-C1</i> gene and mage-c1 protein expression comparison in primary multiple myeloma patients
Published 2022-04-01“…Single factor analysis showed that patients with decreased MAGE-C1 gene and mage-c1 protein expression levels achieved a significantly higher antitumor response to bortezomib-containing regimens, while high expression was accompanied by refractoriness to bortezomib.…”
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1866
Parentage assignment in black soldier fly (Hermetia illucens) using genotyping-by-sequencing
Published 2025-06-01“…However, this is not currently feasible in mass reared insects like BSF. …”
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1867
SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2
Published 2025-07-01“…SFX-01, an α-cyclodextrin-stabilized sulforaphane complex currently in clinical development, covalently adducts cysteine residues. …”
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1868
Molecular identification of Moniliophthora roreri isolates from cocoa orchards in Norte de Santander, Colombia
Published 2016-01-01“…The disease destroys the cocoa pod and crop production decreases, the losses reach up to 60% in the department of Norte de Santander. …”
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1869
The Profile of Multidrug Tuberculosis Regimen and Treatment Outcomes in Pulmonary MDR-TB Patients at the Tertiary Referral Hospital Dr. Soetomo, East Java, Indonesia: A Seven-Year...
Published 2024-01-01“…The treatment outcome profile of MDR-TB patients shows the average percentage of cured (15%), died (12%), lost-to-follow-up cases (27%), moved to an individualized regimen or a different health facility (42%), and currently in the evaluation stage (4%). Overall from January 2017 to July 2022, the number of LTFU cases decreased (42, 46, 29, 19, 8, 4)%. …”
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1870
Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy
Published 2018-01-01“…However, like other stem cell-based therapies, survival of therapeutic NSCs after transplantation is currently suboptimal. One approach to prolonging cell survival is to transiently overexpress an antiapoptotic protein within the cells prior to transplantation. …”
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1871
Optimal Operation Strategy of Ship Power System Under Battle Damage for Enhancing Survivability in Long-Term Missions
Published 2025-07-01“…After a ship suffers an external strike, the system is often in a poor state of battle damage. Currently, the support capacity of the system in all aspects decreases dramatically, the operation interval narrows, and it is not easy to ensure the completion of the long-term mission chain, especially when it involves impact loads, which is more significant. …”
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1872
Curie Temperatures and Emplacement Conditions of Pyroclastic Deposits From Popocatépetl Volcano, Mexico
Published 2022-08-01“…The central part of this sequence is characterized by decreasing magnetic susceptibility and low field dependence of magnetic susceptibility (<10%), which is atypical for ulvöspinel‐rich titanomagnetite. …”
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1873
Role of the Fe<sub>3</sub>O<sub>4</sub> mass ratio in Fe<sub>3</sub>O<sub>4</sub>-Fe nanoparticles with the core-shell structure on their anticancer activity <i>in vitro</i>
Published 2022-09-01“…Using the MTT test, it was found that nanoparticles containing 5 wt. Fe3O4, in the presence of which, at a concentration of 1 mg/ml, the number of living cells decreased to 16 % relative to the control. …”
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1874
The impact of an innovative payment model on the direct economic burden of infectious disease inpatients: evidence from a pilot City in central China
Published 2025-05-01“…These correspond to monthly decreasing slopes of ¥237.96, ¥164.21, ¥124.58, and 0.31%, respectively. …”
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1875
A methionine/aspartate-rich synthetic peptide delineated from N-terminal region of nucleophosmin protein effectively protects against cadmium-induced toxicity
Published 2025-05-01“…The molecular mechanism of Cd cytotoxicity is complicated and still not well understood, and treatment options for Cd cytotoxicity are lacking. Currently, only a limited number of Cd-targeted proteins have been identified. …”
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1876
Identifying studies evaluating susceptibility factors for chemical health assessments: A case study focused on methylmercury developmental neurotoxicity
Published 2025-03-01“…However, at this time, Approach 1, involving the application of a dose–response filter, is currently recommended for identifying epidemiology papers with information on susceptibility factors.…”
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1877
Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes.
Published 2023-01-01“…<h4>Introduction</h4>Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.…”
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1878
Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis
Published 2025-02-01“…LC-treated hiPSC-CM cultures and LC-containing spheroids presented structural and functional defects including: (1) decreased levels and subcellular disorganization of sarcomeric protein alpha-actinin; (2) abnormal accumulation of calcium handling SERCA2a protein; (3) impaired contractility of spheroids and altered calcium transients. …”
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1879
Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia
Published 2020-01-01“…The activation of apoptosis is one of the main molecular mechanisms responsible for anti-cancer activities of most of the currently studied potential anti-cancer agents, including natural compounds. …”
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1880
In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington’s Disease
Published 2025-05-01“…<b>Methods:</b> This study aims to investigate the efficacy of siRNA-containing nano-engineered lipopolymers in selectively silencing the <i>HTT</i> expression in a neuronal model expressing a chimeric protein formed by the human mutated exon 1 of the <i>HTT</i> gene, tagged with GFP. …”
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