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3981
iPSC models of mitochondrial diseases
Published 2025-04-01“…Consequently, most mitochondrial diseases are currently untreatable. Human induced pluripotent stem cells (iPSCs) represent a promising approach for developing human model systems and assessing therapeutic avenues in a patient- and tissue-specific context. iPSCs are being increasingly used to investigate mitochondrial diseases, either for dissecting mutation-specific defects within two-dimensional (2D) or three-dimensional (3D) progenies or for unveiling the impact of potential treatment options. …”
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3982
Enhancing digital literacy in primary education through augmented reality
Published 2024-11-01“…Currently, there is a need to develop digital competencies already because they are included in the new curriculum. …”
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3983
In silico identification of silent primycin biosynthetic gene clusters within the family Pseudonocardiaceae
Published 2025-01-01“…In the global effort to discover or design new effective antibiotics to fight infectious diseases, the increasingly available multi-omics data with novel bioinformatics tools open up new horizons for the exploration of the genetic potential of bacteria to synthesize bioactive secondary metabolites. …”
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3984
THE WEEKEND TOUR AS THE PROSPECTIVE TREND OF RURAL DEVELOPMENT
Published 2024-03-01“…The authors of the article are convinced that the study and adopting the best practices of European countries in the context of a weekend tour will contribute to an increase in income from domestic tourism. …”
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3985
Flavonoid intake in European adults (18 to 64 years).
Published 2015-01-01“…The translation of these findings into the context of the health of the general public requires detailed information on habitual dietary intake. …”
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3986
Mengkriminalisasi Greenwashing: Menjawab Tantangan Perlindungan Konsumen di Era Keberlanjutan
Published 2025-04-01“…This phenomenon has grown alongside increasing public awareness of the importance of environmental sustainability. …”
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3987
Assessing the impact of cryptocurrency usage on cybersecurity: the European Union experience
Published 2023-12-01“…Demonstrating the positive impact of European practices in regulating digital assets opens prospects for further research into the effectiveness of specific regulatory measures and the possibility of adapting them to the Ukrainian context.…”
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3988
Public Private Partnership in the European Union: Experiences in the UK, Germany and Austria
Published 2008-06-01“…The political context of governments differs between the UK, Germany and Austria, but each government currently has a positive view of Public private Partnership (PPP). …”
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3989
Reporting Together: Transactional Sociability, Digital Communities and Alternate Embodiments on the Road through the Use of Waze
Published 2017-11-01“…The paper seeks to fill a gap in digital spatial theory by upholding that apps are made at a fast pace to help increase their commercial value, but their development, design, and research currently lacks critical study. …”
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3990
The evolution and scope of Article 38 of the Convention on the Rights of the Child in a globalizing world
Published 2025-04-01“…Observational method, document examination method, method of analysis and criticism of literature Results The scope of contemporary research on childhood within the context of international discourse reveals the necessity of revising the approach to children and their issues. …”
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3991
THE TAXATION OF IMPUTED INCOME FROM REAL ESTATE LEASING TO PREVENT SHADOWING AND PROPERTY INEQUALITY
Published 2017-09-01“…The neo-industrial development of the Russian economy requires increasing the saving raio of fixed capital. The key source of investment is the savings of households currently underutilized mostly because people prefer to invest in real estate. …”
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3992
SISTEMAS FISIOGRÁFICOS DEL ÁREA NATURAL PROTEGIDA “VALLE CRETÁCICO”, PROVINCIA DE RÍO NEGRO
Published 2011-12-01“…The physiographic systems study shows that there is a marked susceptibility to the erosion processes increase, especially gully erosion. The natural vegetation, as a consequence of its physiognomic characteristics adapted to semiarid and mesothermal climate and of the historical social land use overloading , currently presents a low coverage, associated with low levels of soil aggregation. …”
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3993
Circle of Security - Parenting: A Systematic review on Effectiveness of use of the parent training program within Multi-problem Families
Published 2021-01-01“…COS-p is a widely used parenting programme that is gaining global popularity, as it is currently being delivered across several continents. …”
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3994
Advances in Encapsulating Marine Bioactive Compounds Using Nanostructured Lipid Carriers (NLCs) and Solid Lipid Nanoparticles (SLNs) for Health Applications
Published 2024-11-01“…As life expectancy rises and modern lifestyles improve, there is an increasing focus on health, disease prevention, and enhancing physical appearance. …”
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3995
STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma
Published 2024-01-01“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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3996
Enhancing Acanthamoeba diagnostics: rapid detection of viable Acanthamoeba trophozoites and cysts using viability PCR assay
Published 2025-03-01“…The difference in viable Acanthamoeba was determined by subtracting the cycle threshold (Ct) value of the PMAxx-treated sample from the non-PMAxx-treated sample. Mixtures with decreasing concentrations of viable Acanthamoeba trophozoites and cysts showed increasingly lower delta Ct values as the percentage of viable Acanthamoeba decreased, as expected. …”
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3997
Kalirin, a Key Player in Synapse Formation, Is Implicated in Human Diseases
Published 2012-01-01“…In Kalirin-7 knockout mice, spine length, synapse number, and postsynaptic density (PSD) size are decreased in hippocampal CA1 pyramidal neurons; these morphological alterations are accompanied by a deficiency in long-term potentiation (LTP) and a decreased spontaneous excitatory postsynaptic current (sEPSC) frequency. …”
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3998
Formulation of best-fit hydrophile/lipophile balance-dielectric permittivity demulsifiers for treatment of crude oil emulsions
Published 2016-12-01“…The presence of water in crude oil causes corrosion, lowers capacity utilization of production and processing plant parts and pipelines, reduces oil recovery and increases the oil content of the effluent water. The stabilizing factors of crude oil emulsions vary from one oil field to the other and with time in the same well as co-produced water increases, or after a well treatment and Enhanced Oil Recovery Operations (EOR). …”
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3999
Detection the Expression of two Genes ZmWRKY86 and PMP3 responsible for tolerance to salt stress in maize
Published 2025-06-01“…The current study measured the expression of certain genes responsible for the tolerance of the maize (Zea mays L.) to salt stress when it was grown in soil containing (0.0,25, 50,75,100 mmol) sodium chloride (NaCl) for 30 days. …”
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4000
Paroxysmal Sympathetic Hyperactivity Syndrome (Review)
Published 2022-08-01“…We conclude the review with a discussion of current methods of the syndrome prevention.Conclusion. …”
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