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Copper Increases the Cooperative Gating of Rat P2X2a Receptor Channels
Published 2024-11-01“…<b>Results</b>: In whole-cell recordings and in patches containing 2 or 3 rP2X2a channels, copper enhanced the ATP-induced currents, significantly reducing the ATP EC<sub>50</sub> and increasing the Hill coefficient. …”
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Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
Published 2013-01-01“…Measurements of tetraethylammonium block did not indicate an increased expression of Kv7.5-containing subunits, implying a compensatory increase in Kv7.2 expression from the remaining KCNQ2 gene. …”
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Use of transportability methods for real-world evidence generation: a review of current applications
Published 2024-10-01“…Aim: To evaluate how transportability methods are currently used for real-world evidence (RWE) generation to inform good practices and support adoption and acceptance of these methods in the RWE context. …”
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Cell-penetrating peptides containing the progesterone receptor polyproline domain inhibits EGF signaling and cell proliferation in lung cancer cells.
Published 2022-01-01“…Non-small cell lung cancer (NSCLC) accounts for the majority (80-85%) of all lung cancers. All current available treatments have limited efficacy. …”
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Characterization of a novel Leishmania antigen containing a repetitive domain and its potential use as a prophylactic and therapeutic vaccine
Published 2025-05-01“…ABSTRACT Human visceral leishmaniasis (HVL) is the second most lethal tropical parasitic disease. Currently, no prophylactic or therapeutic vaccines exist for HVL. …”
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ESTIMATION OF CURRENT DYNAMICS AND FORECAST OF GLACIOLOGICAL CHARACTERISTICS OF THE MALYI AKTRU GLACIER (CENTRAL ALTAI)
Published 2018-05-01“…In the context of global and regional climatic changes in the Altai mountain region, observations performed in 1949–2014 demonstrated evident rises of air temperatures, both annual and seasonal means. …”
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Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA-A0201.
Published 2025-01-01“…However, such modifications are increasingly recognized as critical mediators of peptide immunogenicity. …”
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Carbon‐coated current collectors in lithium‐ion batteries and supercapacitors: Materials, manufacture and applications
Published 2024-12-01“…However, as battery systems evolve and the demand for higher energy density increases, the limitations of traditional current collectors, such as high contact resistance and low corrosion resistance, have become increasingly evident. …”
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