Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration by Andjela Sekulic, Sarah M. Herr, Kelly Mulfaul, Inga-Marie Pompös, Silvia Winkler, Carola Dietrich, Benedikt Obermayer, Robert F. Mullins, Thomas Conrad, Peter F. Zipfel, Florian Sennlaub, Christine Skerka, Olaf Strauß

“…Polymorphisms in complement factor-H increase, while absence of factor-H-related protein-1 (FHR1) decreases the AMD risk, currently explained by their opposing relationship. …”
Get full text

NMDA Receptor–Mediated Ca2+ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin by Jordan Casby, Benjamin M. Gansemer, Stanley A. Thayer

“…Incubating cultures in Mg2+‐free buffer containing tetrodotoxin, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione, and bicuculline for 30 min inhibited NMDA‐evoked increases in intracellular Ca2+ concentration ([Ca2+]i) recorded at 22°C by 50% ± 18% and prevented inhibition by brophenexin. …”
Get full text

DYNAMO-A: A generic simulation model coupling crop growth and disease epidemic. by Laetitia Willocquet, Simone Bregaglio, Roberto Ferrise, K H Kim, Serge Savary

“…Future modelling with DYNAMO-based models should enable interdisciplinary research addressing plant disease impacts on current and future agricultural production.…”
Get full text

Histopathological study of the testes in three genetic lines of Japanese quail (Coturnix japonica) exposed to different doses of L-Arginine by Ahmed Shaker, israa Abd Alsada, Questan Ameen, Luay Alsalihi, Adel Hussen

“…Birds were divided by color into three groups and fed diets containing different arginine levels from age 30 to 90 days. …”
Get full text

An Innovation Machine Learning Approach for Ship Fuel-Consumption Prediction Under Climate-Change Scenarios and IMO Standards by Bassam M. Aljahdali, Yazeed Alsubhi, Ayman F. Alghanmi, Hussain T. Sulaimani, Ahmad E. Samman

“…A sensitivity analysis identified vessel speed as the most critical factor, contributing 33% to the variance in fuel consumption, followed by engine power and current speed. Climate-change simulations showed that fuel consumption increases by an average of 22% for bulk carriers and 19% for container ships, highlighting the importance of operational optimizations. …”
Get full text

Proteases from Entamoeba spp. and Pathogenic Free-Living Amoebae as Virulence Factors by Jesús Serrano-Luna, Carolina Piña-Vázquez, Magda Reyes-López, Guillermo Ortiz-Estrada, Mireya de la Garza

“…We also include proteases used by amoebae to degrade iron-containing proteins because iron scavenger capacity is currently considered a virulence factor for pathogens. …”
Get full text

Sirtuins and Their Role in the Aging Eye (Review) by L. K. Moshetova, O. I. Abramova, K. I. Turkina, M. K. Nurbekov, O. P. Dmitrenko, I. N. Saburina, S. A. Kochergin

“…The magnitude of this problem is becoming increasingly apparent as the population ages and the number of older people increases. …”
Get full text

In vitro and preclinical evaluation of the antifungal activity of 6-methoxy-1 H-indole-2-carboxylic acid produced by Bacillus toyonensis strain OQ071612 formulated as nanosponge hy... by Sayed E. El-Sayed, Neveen A. Abdelaziz, Ghadir S. El-Housseiny, Khaled M. Aboshanab

“…Abstract Background In a previous study, 6-methoxy-1 H-indole-2-carboxylic acid (MICA) was isolated from the culture broth of Bacillus toyonensis strain OQ071612 soil isolate in our laboratory, and it demonstrated promising antifungal activities. The current study was designed to create a nanosponge (NS)-hydrogel (HG)-containing MICA followed by in vitro and preclinical evaluation for potential clinical use in the topical treatment of mycotic infections. …”
Get full text

Combined Oral Contraceptives for Polycystic Ovary Syndrome: <i>Pro</i> and <i>Contra</i> (Review) by I. A. Mazerkina, I. G. Davydov, O. S. Alyautdina

“…This study aimed to review current data on the use of COCs in PCOS, focusing on the rationality of prescribing, the main risks of using COCs, and the measures to minimise these risks.DISCUSSION. …”
Get full text

miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Abstract Purpose Polycystic ovary syndrome (PCOS) is currently recognized as a condition that affects several systems in the body, including the reproductive, endocrine, and cardiovascular systems. …”
Get full text

Dying of starvation if not from bombs: assessing measurement properties of the Food Insecurity Experiences Scale (FIES) in Gaza’s civilian population experiencing the world’s worst... by Feten Fekih-Romdhane, Kamel Jebreen, Tasnim Swaitti, Mohammed Jebreen, Eqbal Radwan, Wafa Kammoun-Rebai, Inad Nawajah, Omar Shamsti, Sahar Obeid, Souheil Hallit

“…To achieve this, field practitioners, researchers and decision-makers should be equipped with user-friendly and psychometrically sound measures tailored to real-life war situations and the Palestinian context. Therefore, the present study aimed to test the psychometric properties of the Food Insecurity Experiences Scale (FIES) in a sample of Arabic-speaking community adults currently living in the Gaza Strip during the war. …”
Get full text

Optimization of Physicochemical Parameters during the Electrocoagulation Cadmium Elimination by Abdelaaziz Aityoub, Abdesselam Abouelfida, Abdelaziz Benyaich, Abderrahmane Romane, Mohamed Elmeray, Rachid Idouhli, Yassine Koumya, Mohyeddine Khadiri

“…The increased use of fertilizers from phosphates in agriculture generates water pollution by heavy metals contained in these phosphates at levels higher than the standards. …”
Get full text

NECROSIS AS A COMPLICATION OF LOCAL ANESTHESIA IN DENTISTRY by V.V. Lepsky, C. V. Osik

“…However, as a rule, most of the groups of painkillers contain vasoconstrictors of the cartridge, such as adrenaline hydrochloride, noradrenaline, although the last one is currently banned for use because of the complications that it can cause. …”
Get full text

Immuno‐Nanocomplexes Target Heterogenous Network of Inflammation and Immunity in Myocardial Infarction by Fan Su, Weifan Ye, Yi Shen, Yujie Xie, Chong Zhang, Qianyun Zhang, Zhengqi Tang, Meihua Yu, Yu Chen, Bin He

“…Abstract Despite the proceeds in the management of acute myocardial infarction (AMI), the current therapeutic landscape still suffers from limited success in the clinic. …”
Get full text

Bridging inflammation and venous thrombosis: the NLRP3 inflammasome connection by Jian Wu, Jian Wu, Zilong Wang, Zilong Wang, Wei Shao, Wei Shao, Jianwen Mo

“…In recent years, research has increasingly focused on the role of the NLRP3 inflammasome in venous thromboembolism (VTE). …”
Get full text

Acute Oak Decline-Associated Bacteria: An Emerging Worldwide Threat to Forests by Alessandro Bene, Marzia Vergine, Giambattista Carluccio, Letizia Portaccio, Angelo Giovanni Delle Donne, Luigi De Bellis, Andrea Luvisi

“…The potential involvement of xylophagous insects is also being studied, particularly <i>Agrilus biguttatus</i>, which, although, frequently associated with the disease, has not been conclusively demonstrated to act as an active vector of the bacteria. Currently, disease management requires integrated approaches, including monitoring and other forestry strategies to increase forest resilience. …”
Get full text

Seawater Corrosion Resistance of Cold Spray Al₂O₃ - Al - xY Coating on Q295B Surface of Building by YANG Lei, ZHU Fu - li, ZHANG Hao, BAI Bo

“…After soaking the coating with Y content of 0.2% for 700 h, a higher anode polarization rate was obtained and the lowest corrosion current density reached. The corrosion products of Al2O3&#x00A0;- Al -&#x00A0;xY coating contained Al and Al2O3. …”
Get full text

Simultaneous Separation of Runoff Pathways and Storage Times via Coupled Electrical Conductivity Mass Balance and Nonlinear Storage‐Discharge Relationship: Theory and Application T... by Weifei Yang, Changlai Xiao, Xiujuan Liang, Zhang Fang, Dianwu Song

“…The added consideration of the impacts of passive storage and water‐rock interaction significantly increases the reproducibility of streamflow EC and also leads to more similar baseflow and old water separation, which in fact have significant differences due to distinct components they contain. …”
Get full text

Numerical Responses of <i>Xylocoris flavipes</i> (Reuter) (Hemiptera: Anthocoridae) on a Diet of <i>Liposcelis decolor</i> (Pearman) (Psocodea: Liposcelididae) by Augustine Bosomtwe, George Opit, Carla Goad, Kristopher Giles, Brad Kard

“…Insect predators can suppress prey populations through increased progeny production. The present study investigated the numerical responses of adult♀ <i>Xylocoris flavipes</i> (Reuter) (Hemiptera: Anthocoridae) on a diet of <i>Liposcelis decolor</i> (Pearman) (Psocodea: Liposcelididae). …”
Get full text

Transition From Scenario-Based to Outcome-Based Engineering in SE4AI by Niloofar Shadab, Alejandro Salado, Tyler Cody, Peter Beling

“…As intelligent systems become increasingly integrated into our daily lives, it has become evident that there is a mismatch between traditional systems engineering (SE) practices and the nature of intelligent systems. …”
Get full text