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1321
Blood-based biomarkers in mild behavioral impairment: an updated overview
Published 2025-02-01“…A growing number of studies have recently begun to explore the relationship between MBI and several blood-based biomarkers associated with Alzheimer’s disease (AD) pathology, neurodegeneration, as well as systemic metabolic and inflammatory dysregulation. In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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1322
The Role of Extracellular Vesicles in Aging and Age-Related Disorders
Published 2025-02-01“…Mitochondrial malfunction and increased oxidative stress are major contributors for the aging process. …”
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1323
Assessment of Health-Oriented Layout and Perceived Density in High-Density Public Residential Areas: A Case Study of Shenzhen
Published 2024-11-01“…The authors attempt to go beyond current regulations to propose tailored solutions for Shenzhen’s high-density context, improving spatial efficiency and residential comfort in future public housing designs. …”
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1324
Crop simulation models as decision tools to enhance agricultural system productivity and sustainability – a critical review
Published 2025-01-01“…Feeding the growing global population necessitates increased agricultural production, yet agriculture remains a vulnerable sector facing significant challenges from limited land resources, environment, and climatic constraints. …”
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1325
Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade
Published 2024-11-01“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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1326
The frequent variant A57F in the GNE gene in patients from Russia has Finno-Ugric Mari origin
Published 2024-12-01“…According to our study, the estimated age of the mutation’s spread is 160.46 years (95% CI: 45.55–244.14).DiscussionBy comparing the information gathered with historical data on migration patterns in the Middle Volga region and estimating the age of the variant’s dissemination, we propose hypotheses regarding its origin and the pathways through which it spread. In the current context of increased rate of interethnic marriages, investigating the spread of common pathogenic variants from historically isolated populations is important for molecular genetic diagnosis. …”
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1327
Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories
Published 2025-05-01“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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1328
NFT UNDER CONDITIONS OF CRITICAL TRANSFORMATIONS IN THE DIGITAL ASSET MARKET
Published 2025-04-01“…The article presents an analysis of the NFT market with a focus on its structural changes. The current state of the non-fungible token market is characterised by a shift from speculation to increased utility of NFTs in various sectors. …”
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1329
The CeHRes Roadmap 2.0: Update of a Holistic Framework for Development, Implementation, and Evaluation of eHealth Technologies
Published 2025-01-01“… To ensure that an eHealth technology fits with its intended users, other stakeholders, and the context within which it will be used, thorough development, implementation, and evaluation processes are necessary. …”
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1330
Publishing Identifiable Patient Photographs in the Digital Age: Focus Group Study of Patients, Doctors, and Medical Students
Published 2025-03-01“…Additionally, it sought to identify key areas for future research, particularly in the context of online, open-access articles. …”
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1331
Efficient utilization of high CO2 landfill-gas for syngas generation: Ultra-rich combustion pathways study in porous media reactor via CFD simulation
Published 2025-03-01“…The current investigation explores the possibility of extracting syngas from low-calorific value landfill-gas rich-combustion with pure O2, which contains a considerable amount of CO2 in its composition as an effective strategy in CO2 utilization. …”
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1332
Electrohydraulic effect of microsecond pulsed discharge in transformer oils
Published 2025-02-01“…With the gap distance increase, all the breakdown voltage, the discharge energy, and the ratio of the mechanical energy to total energy increase, the breakdown current, the acceleration of the container wall, and the velocity of the shock wave decrease. …”
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1333
Tuberculosis mortality and drug resistance among patients under TB treatment before and during COVID-19 in Burundi: a case–control study
Published 2025-05-01“…Conclusion TB mortality increased during the COVID-19 pandemic, particularly among MDR-TB patients. …”
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1334
The effect of biofertilizer on water regime, intensity of photosynthesis and productivity of grain crops in the Steppe Pre-Urals
Published 2025-03-01“…There has been established a water deficit increase of grain crops in milk stage and its reliable decrease in the biomass of spring common wheat and barley when using biofertilizers in comparison with the control variants. …”
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1335
Comprehensive analysis of the mechanisms conferring resistance to phenamacril in the Fusarium species
Published 2025-02-01“…We emphasize the importance of continued research and integrating different approaches to monitoring and managing drug-resistant Fusarium spp. populations. Integrating current inventions to inform strategies for sustainable disease control practices, and increase plant health, and yield will contribute to ongoing global efforts to achieve food and nutritional sustainability for the world's rapidly growing population while ensuring the effectiveness of the fungicidal product.…”
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1336
Research progress of treated dentin matrix in vital pulp therapy
Published 2025-04-01“…There has been an increase in research interest and application of treated dentin matrix (TDM) in vital pulp therapy (VPT) in recent years. …”
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1337
Psycholinguistic Aspects of the Semantic Field of the Concept “War” in Modern Media Space
Published 2018-04-01“…We underlined the link between the changes in the forms of international conflicts and the increase of the units contributing to the semantic field of the concept “war”. …”
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1338
Adipokines as Cardioprotective Factors: BAT Steps Up to the Plate
Published 2025-03-01“…The molecules secreted specifically by BAT have been termed “batokines”, and currently available evidence supports the notion that batokines exert favorable metabolic effects on multiple organ systems. …”
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1339
Technical, forensic and organisational aspects of work with Monero cryptocurrency
Published 2023-09-01“…The forensic, organisational and technical features of law enforcement agencies' work with the Monero cryptocurrency in the context of pre-trial investigation and operational search activities are analysed. …”
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1340
Infinity war: Trichomonas vaginalis and interactions with host immune response
Published 2023-03-01“…Endosymbi-osis: Mycoplasma hominis increased cytotoxicity, growth, and survival rate of the parasite. …”
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