Novel chlorine-containing curcumin analogue CAK06 promotes neuroprotection and rapid antidepressant through Nrf2-induced anti-inflammatory and antioxidant effects by Tao Chen, Suyu Yin, Ruxu Yue, Chao Pi, Ying Zuo, Yongqiang Jiang, Wenwu Zheng, Jun Jiang, Yan Yang, Shifeng Chu, Kezhi Liu, Yumeng Wei, Ling Zhao

“…Currently, conventional antidepressants are often limited by poor efficacy and delayed onset, and there is an urgent need for the development of rapid acting antidepressant alternatives. …”
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Quantifying Flavin mononucleotide: an internationally validated methodological approach for enhanced decision making in organ transplantationResearch in context by Keyue Sun, Chunbao Jiao, Rebecca Panconesi, Sangeeta Satish, Omer F. Karakaya, Femke H.C. De Goeij, Tobias Diwan, Khaled Ali, Lorenzo A. Cadinu, Beatrice Cazzaniga, Qiang Liu, Yuki Miyazaki, Alejandro Pita, Mazhar Khalil, JaeKeun Kim, Ahmed Hussein, Philipp C. Müller, Federico Aucejo, David H.C. Kwon, Eduardo Fernandes, Jamak Modaresi Esfeh, Jacek Cywinski, Masato Fujiki, Lidong Sun, Antonio Pinna, Philipp Dutkowski, Chase J. Wehrle, Robert L. Fairchild, David Meierhofer, Jeroen De Jonge, Charles Miller, Koji Hashimoto, Andrea Schlegel

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A Bibliometric Analysis of Mountain Research Literature on Journal of Mountain Research and Development: Current Situation and Future Directions by İsmet Güney, Merve Altundal Öncü, Burcu Göközkut, Mehmet Somuncu

“…Academic studies on mountains have increased since the 1990s. The aim of this study is to examine the current situation and development of the international literature on mountainous areas. …”
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Tailoring consent to context: designing an appropriate consent process for a biomedical study in a low income setting. by Fasil Tekola, Susan J Bull, Bobbie Farsides, Melanie J Newport, Adebowale Adeyemo, Charles N Rotimi, Gail Davey

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Cancer Vulnerabilities Through Targeting the ATR/Chk1 and ATM/Chk2 Axes in the Context of DNA Damage by Anell Fernandez, Maider Artola, Sergio Leon, Nerea Otegui, Aroa Jimeno, Diego Serrano, Alfonso Calvo

“…In the modern era of personalized medicine, this strategy tries to identify specific vulnerabilities found in each patient’s tumor, to inflict DNA damage in certain cell contexts that end up in massive cancer cell death. …”
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Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK by Jennifer K Quint, Helene Vioix, Toby Capstick, Sue Langham, Jennifer Cook, Antony Wright, Shamika de Silva

“…Savings were achieved overall despite a small increase in the rate of exacerbations due to the redistribution of certain patients currently undergoing triple inhaled therapy to therapies not containing inhaled corticosteroids.Conclusion Redistribution of patients with COPD from current clinical practice to treatment according to published recommendations would provide substantial cost savings over the first year.…”
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Citizens’ perspectives on sustainable mobility transitions in a semi-urban context: tensions between everyday practices and sustainability advancements by Jonas Ihlström, Karolina Isaksson, Jonna Nyberg

“…As illuminated in the studied semi-urban context, many established everyday practices are car-dependent. …”
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Knowledge and Perception of Practicing Anesthetists on Current Techniques, Clinical Applications, and Limitations of Artificial Intelligence in Anesthesiology: An Indian Study by Manasij Mitra, Maitraye Basu, Amrita Ghosh, Ranabir Pal

“…Background: Artificial intelligence (AI) is increasingly gaining importance in modern medicine. Yet, there is a dearth of knowledge on what the anesthesiologists know and think about AI in context. …”
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Subunit-specific mechanisms of isoflurane-induced acute tonic inhibition in dentate gyrus granule neuron by Zhiqiang Yu, Xiaodan Chen, Zheng Liu, Ran Ding, Jin Xu

“…Furthermore, this study demonstrated that the increased tonic current in DGGCs was dependent on the δ subunit-containing GABAARs by using transgenic δ subunit knockout mice. …”
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Applications of Machine Learning (ML) in the context of marketing: a bibliometric approach [version 2; peer review: 2 approved] by Erica Agudelo-Ceballos, Ezequiel Martínez Rojas, Sebastián Cardona-Acevedo, Carlos Flores Goycochea, Juana De La Cruz Ramírez Dávila, Diana Arango-Botero, Jesus Alberto Jimenez Garcia, Alejandro Valencia-Arias

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Gathering insights of the global scenario of floating-bed agriculture through systematic literature review for its promotion in Indian context by Tanmoy Kumar Ghosh, Ashish Kumar Singh, Sudip Mitra, Sougata Karmakar

“…This literature review aims to comprehensively document the current global scenario of floating-bed agriculture to promote it in India. …”
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The effectiveness of home-based transcranial direct current stimulation on chronic pain: A systematic review and meta-analysis by Annibale Antonioni, Andrea Baroni, Giulia Fregna, Ishtiaq Ahmed, Sofia Straudi

“…As pain is highly prevalent and imposes significant burdens, interest in its remote management is steadily increasing. Transcranial Direct Current Stimulation (tDCS) seems promising in this context. …”
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The Comprehensive-Adaptive Approach to the Innovative Development of the Enterprise in the Current Trends of Digitalization through the Interaction of External and Internal Factors by Arefieva Olena V., Dolzhenko Dmytro Yu.

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Unraveling the Complexity of the Ne/Nc Ratio for Conservation of Large and Widespread Pelagic Fish Species: Current Status and Challenges by Chrystelle Delord, Sophie Arnaud‐Haond, Agostino Leone, Jonathan Rolland, Natacha Nikolic

“…Secondly, we outline current knowledge about the influence of life history traits on the Ne/Nc ratio in the light of examples drawn from large and abundant pelagic fish species. …”
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Integrating sequencing methods with machine learning for antimicrobial susceptibility testing in pediatric infections: current advances and future insights by Zhuan Zou, Zhuan Zou, Fajuan Tang, Fajuan Tang, Lina Qiao, Lina Qiao, Sisi Wang, Sisi Wang, Haiyang Zhang, Haiyang Zhang

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Use of Artificial Intelligence in Adolescents’ Mental Health Care: Systematic Scoping Review of Current Applications and Future Directions by Gauri Sharma, Mark J Yaffe, Pooria Ghadiri, Rushali Gandhi, Laura Pinkham, Genevieve Gore, Samira Abbasgholizadeh-Rahimi

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A FRAME Model-based Investigation into the Implementation of M-Learning in Classrooms from the Perspectives of Vietnamese High School Teachers and Students in Southern Vietnam by Bao Thien Nguyen, Yau-Jane Chen

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A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosisResearch in context by Jeremy S. Lum, Mikayla L. Brown, Natalie E. Farrawell, Rachael Bartlett, Christen G. Chisholm, Jody Gorman, Anthony Dosseto, Florian Dux, Lachlan E. McInnes, Heath Ecroyd, Luke McAlary, Peter J. Crouch, Paul S. Donnelly, Justin J. Yerbury

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A Critical Analysis of Cooperative Caching in Ad Hoc Wireless Communication Technologies: Current Challenges and Future Directions by Muhammad Ali Naeem, Rehmat Ullah, Sushank Chudhary, Yahui Meng

“…In this paper, we discuss the problems and issues in the current wireless ad hoc paradigms as well as spotlight versatile cooperative caching as the potential solution to the increasing complications in ad hoc networks. …”
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Approaches to clinical development of combination medicines in the Russian Federation and the Eurasian Economic Union in view of the requirements of the current legislation by A. V. Dobrovolskiy

“…In recent years, there has been an increasing interest in the development of combination medicines (fixed drug combinations) containing two or more active ingredients in a single dosage form. …”
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