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  1. 4501

    A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX by Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Matthew Anson, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Astrid Dempfle, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Sizheng S. Zhao, Uazman Alam, Uazman Alam, Uazman Alam

    Published 2025-03-01
    “…TriNetX’s federated network architecture allows real-time, privacy-compliant data access, significantly enhancing the ability to conduct retrospective studies and refine clinical trial designs. With access to currently over 150 million EHRs, TriNetX has proven particularly effective in filling gaps left by RCTs, especially in the context of rare diseases, rare endpoints, and diverse patient populations. …”
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  2. 4502
  3. 4503

    The state of drained peatlands in the Middle Urals and prospects of their use for carbon farming by Seyed Omid Reza Shobairi, Alenakochubei, Olga Cherepanova, et al.

    Published 2025-06-01
    “…The global change of the planet's climate is associated with increased concentration of greenhouse gases in the atmosphere, which is the result of irrational human economic activity. …”
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  4. 4504

    Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34+ Cells by Hui Xie, Li Sun, Liming Zhang, Teng Liu, Li Chen, Aiqi Zhao, Qian Lei, Fei Gao, Ping Zou, Qiubai Li, An-yuan Guo, Zhichao Chen, Hongxiang Wang

    Published 2016-01-01
    “…We speculate that MSC-MVs may recapitulate the hematopoiesis-supporting effects of their parent cells. In the current study, we found MSC-MVs containing microRNAs that are involved in the regulation of hematopoiesis. …”
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  5. 4505

    Inhibition of corrosion of mild steel hull plates immersed in natural sea water by sandalwood oil extract of some natural products by Thankappan Sasilatha, Rajendran Susai Santhammal, Hashem Abdulhameed Al, Časlav Lačnjevac, Gurmeet Singh

    Published 2022-03-01
    “…When mild steel is immersed in Oil coated (3 days) MS in SW+ SDP 100 ppm+ Zn2+ 50ppm system , the corrosion resistance of MS increases. This is revealed by the fact that there is increase in LPR value and decrease in corrosion current value. …”
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  6. 4506

    Optimization of The Budget of The Industrial Complex Transformation Strategy Based on Neural Network Modeling by A. G. Boev, A. G. Puzakov, Yu. P. Anisimov

    Published 2022-06-01
    “…Currently, Russian industry is developing mainly along an extensive path that does not provide a deep innovative transformation of business and the necessary increase in labor productivity.Materials and methods. …”
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  7. 4507

    Role of tertiary lymphoid structures and B cells in clinical immunotherapy of gastric cancer by Weiyi Chen, Lingli Zhang, Man Gao, Ning Zhang, Rumeng Wang, Yang Liu, Yan Niu, Lizhou Jia, Lizhou Jia

    Published 2025-01-01
    “…Mature TLSs are B-cell regions containing germinal centers. During germinal center formation, B cells undergo transformations to become mature cells with immune function, exerting anti-tumor effects. …”
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  8. 4508

    Fatty fried food toxins as triggering stimuli to immune system interplay in global autoimmune diseases: A systematic review by Saba Anwar, Qamar Abbas Syed, Mahnoor Saleh, Muhammad Saad Akram, Ghayyor Sultan, Sahar Khalid, Anum Ishaq, Gholamreza Abdi, Rana Muhammad Aadil

    Published 2025-03-01
    “…The purpose of the current systematic review was to respond to the following query: Does the rising level of fatty fried food consumption trigger the major autoimmune diseases such as Crohn's disease, ulcerative colitis, rheumatoid arthritis, systemic lupus erythematous, and multiple sclerosis? …”
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  9. 4509

    Topological transformation of microbial proteins into iron single-atom sites for selective hydrogen peroxide electrosynthesis by Xiaofeng Xiao, Zechao Zhuang, Shuhu Yin, Jiexin Zhu, Tao Gan, Ruohan Yu, Jinsong Wu, Xiaochun Tian, Yanxia Jiang, Dingsheng Wang, Feng Zhao

    Published 2024-12-01
    “…These moieties resemble the structural features of nonheme Fe-dependent enzymes while being effectively confined on a microbe-derived, electrically conductive carbon support, enabling high-current density electrolysis. A comparative analysis involving catalysts derived from eleven representative microbes reveals that the presence of 0.05 wt% Fe single-atom sites leads to a significant 26% increase in hydrogen peroxide selectivity. …”
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  10. 4510
  11. 4511

    EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): protocol for a systematic review, network meta-analysis a... by Ian Sinha, Dyfrig A Hughes, Michelle Maden, Stephen Turner, Sofia Cividini, Sarah Donegan, Giovanna Culeddu, Katie Rose, Olive Fulton, Catrin Tudur Smith

    Published 2021-02-01
    “…Treatment with a low-dose ICS, however, fails to control asthma symptoms in around 10%–15% of children and this places the individual at increased risk for an asthma attack. At present, there is no clear preferred treatment option for a child whose asthma is not controlled by low-dose ICS and international guidelines currently recommend at least three treatment options. …”
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  12. 4512

    Assessing and Enhancing Nutrition and Physical Activity Environments in Early Childhood Education and Care Centers: Scoping Review of eHealth Tools by Joyce Hayek, Kelsi Dickson, Lynne M Z Lafave

    Published 2025-01-01
    “…Eligibility criteria were (1) early childhood educators (population); (2) eHealth (digital) technologies, such as websites, smartphone apps, emails, and social media; and (3) tools designed to assess or deliver interventions aimed at improving best practices for nutrition, physical activity, or both within ECEC settings (context). A search was conducted across 5 electronic databases (PubMed, Scopus, CINAHL Plus, ERIC, and Embase) to identify white literature, and 3 electronic databases (ProQuest, Google Scholar, and targeted Google search), along with hand-searching of reference lists, were used to identify gray literature. …”
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  13. 4513

    Is drought protection possible without compromising flood protection? Estimating the potential dual-use benefit of small flood reservoirs in southern Germany by S. Q.-G. Ho, S. Q.-G. Ho, S. Q.-G. Ho, U. Ehret, U. Ehret

    Published 2025-07-01
    “…<p>As climate change drives the intensification and increased frequency of hydrological extremes, the need to balance drought resilience and flood protection becomes critical for proper water resources management. …”
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  14. 4514

    Application of Jane Jacobs’ Theory in the Analysis of the Borders of Territory Monitoring in Urban Spaces from Citizens’ Points of View in Bandar Abbas by Amirhamzeh Shahbazi, Esmaeil zakerimnabi, Alireza Shahbazi

    Published 2025-06-01
    “…The city exhibits a heterogeneous and multicultural context characterized by both modern influences and traditional customs that have persisted over time. …”
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  15. 4515

    Optimizing AI models to predict esophageal squamous cell carcinoma risk by incorporating small datasets of soft palate images by Kotaro Waki, Katsuya Nagaoka, Keishi Okubo, Masato Kiyama, Ryosuke Gushima, Kento Ohno, Munenori Honda, Akira Yamasaki, Kenshi Matsuno, Yoki Furuta, Hideaki Miyamoto, Hideaki Naoe, Motoki Amagasaki, Yasuhito Tanaka

    Published 2025-02-01
    “…Previously, we found that specific soft palate morphologies are strongly associated with increased ESCC risk. However, there is currently no artificial intelligence (AI) system that utilizes oral images for ESCC risk assessment. …”
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  16. 4516

    Natural and Waste Materials for Desulfurization of Gaseous Fuels and Petroleum Products by Iliya Iliev, Antonina Filimonova, Andrey Chichirov, Alena Vlasova, Ruzina Kamalieva, Ivan Beloev

    Published 2025-02-01
    “…Natural gas, refinery gas, and coal gas contain acid gases such as hydrogen sulfide and carbon dioxide. …”
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  17. 4517

    Enabling High-Level Worker-Centric Semantic Understanding of Onsite Images Using Visual Language Models with Attention Mechanism and Beam Search Strategy by Hui Deng, Kejie Fu, Binglin Yu, Huimin Li, Rui Duan, Yichuan Deng, Jia-rui Lin

    Published 2025-03-01
    “…Visual information is becoming increasingly essential in construction management. However, a significant portion of this information remains underutilized by construction managers due to the limitations of existing image processing algorithms. …”
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  18. 4518

    Excessive Fe Contamination in Secondary Al Alloys: Microstructure, Porosity, and Corrosion Behaviour by Helder Nunes, Rui Madureira, Manuel F. Vieira, Ana Reis, Omid Emadinia

    Published 2025-04-01
    “…The characterisation of aluminium casting alloys with iron concentrations exceeding current standards is essential, as upcycling has recently become a significant concern in achieving a more circular economy. …”
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  19. 4519

    The new peas variety “Pamyati Popova” by F. A. Davletov, G. М. Nigmatullina, К. P. Gaynullina, А. V. Pleshkov, F. F. Safn

    Published 2020-06-01
    “…According to the Competitive Variety Testing, the average yield increase of the variety “Pamyati Popova” was on 3.9 hwt/ha in 2016–2019. …”
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  20. 4520

    Complete mitochondrial genomes of the Prototheca genus: comparative genomics and evolutionary insights by Daniel Wibberg, Zofia Bakuła, Iván García-Cunchillos, Jan Gawor, Robert Gromadka, Anna Karnkowska, Jacek Bielecki, Tomasz Jagielski

    Published 2025-08-01
    “…In this study, a combination of Illumina and Oxford Nanopore technologies was employed for sequencing of 18 mitochondrial genomes, representing all currently recognized Prototheca species. Results The genomes differed in terms of size and GC content, ranging from 38 kbp to 68 kbp and from 25 to 30%, respectively. …”
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