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2801
DIRECTIONS FOR THE DEVELOPMENT OF ORGANIC FARMING IN SIBERIA ON THE INNOVATIVE AND INVESTMENT BASIS
Published 2023-01-01“…The transition to highly productive and environmentally friendly agricultural farming is one of the priorities of the Strategy for Scientific and Technological Development of the Russian Federation. In the current conditions of sanctions policy, the need for a large-scale transfer of agriculture to organic farming increases. …”
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2802
Exploring the Role of Artificial Intelligence in Wastewater Treatment: A Dynamic Analysis of Emerging Research Trends
Published 2024-12-01“…Wastewater treatment is a critical process for ensuring water quality and public health, particularly in the context of increasing environmental challenges such as pollution and water scarcity. …”
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2803
Incidental findings related to genes associated to HAE-nC1INH: how to proceed?
Published 2025-06-01“…The mainstreaming of genomic technology and the increasing use of next generation sequencing have increased the possibility of an unintentional detection of HAE-nC1INH pathogenic variants and allowed the incidental finding of variants of uncertain significance (VUS) in the relevant genes. …”
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2804
Identification of an intrinsic determinant critical for maspin subcellular localization and function.
Published 2013-01-01“…Taken together, our evidence demonstrates that D(346) is a critical cis-element in maspin sequence that determines the molecular context and subcellular localization of maspin. A mechanistic model derived from our evidence suggests a new window of opportunity for the development of maspin-based biologically competent HDAC inhibitors for cancer treatment.…”
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2805
Gender differences in use of cigarette and non-cigarette tobacco products among adolescents aged 13–15 years in 20 African countries
Published 2024-01-01“…Among girls, higher levels of reported exposure to tobacco advertisement were positively associated with shisha smoking whereas perceived tobacco harm was inversely associated with current cigarette and shisha smoking. Among boys, perceived social acceptability of smoking at parties was associated with an increased likelihood of cigarette smoking (APR=2.27; 95% Cl: 1.20–4.30). …”
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2806
Application of Cord Blood–Derived Exosomes in Tumor Prevention and Treatment
Published 2025-08-01“…This narrative review examines the current application status of CB-derived EXOs in tumor prevention and treatment: in the context of tumor treatment, it focuses on their direct therapeutic application and their use as drug carriers; regarding tumor prevention, it explores their application in cancer vaccines. …”
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2807
Advancements in textile techniques for cardiovascular tissue replacement and repair
Published 2024-12-01“…These techniques are evaluated in the context of fabricating cardiac patches, vascular graft constructs, stent designs, and state-of-the-art wearable sensors. …”
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2808
Leveraging green innovation from big data analytics: Examining the role of resource orchestration and green dynamic capabilities
Published 2024-01-01“…PURPOSE: The notion of big data analytics (BDA) has received increased attention from both researchers and managers. …”
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2809
Does use of domestic insecticides undermine public health control strategies?
Published 2025-05-01“…Current research has predominantly examined resistance development in the context of public health interventions and agricultural applications. …”
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2810
Comparison of Grammar Characteristics of Human-Written Corpora and Machine-Generated Texts Using a Novel Rule-Based Parser
Published 2025-03-01“…We further examine the stability of this criterion in the context of AI humanization and translation to other languages.…”
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2811
Modeling Approaches for Accounting Radiation-Induced Effect in HVDC-GIS Design for Nuclear Fusion Applications
Published 2024-12-01“…A key challenge in this context is the degradation of dielectric performance due to radiation-induced conductivity (RIC), a phenomenon specific to the harsh radioactive environments near fusion reactors. …”
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2812
Trends in prevalence and patterns of use of a heated tobacco product (IQOS™) in Japan: A three-year repeated cross-sectional study [version 2; peer review: 1 approved, 2 approved w...
Published 2022-11-01“…Background: Numerous smoke-free tobacco or nicotine-containing product (TNP) alternatives have been introduced to support individual- and population-level harm reduction relative to continued cigarette smoking. …”
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2813
Optimal Scheduling of the Wine-Bottling Process: A Multi-Dependency Model with Hydraulic Considerations
Published 2025-04-01“…This study addresses the optimization of the bottling process in the wine industry, focusing particularly on the filtration stage, which accounts for approximately 30% of the total costs in the value chain. In the context of significant global production, but with challenges arising from declining demand and increasing costs, precise planning becomes necessary to ensure product quality and operational efficiency in order to control and minimize the costs associated with resource usage. …”
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2814
The role of nicotinamide-β-adenine dinucleotide phosphate-H-cytochrome P450 oxidoreductase in the activation of cytochromes
Published 2025-01-01“…The aim of this theoretical study is to investigate the mechanisms of action of these enzymes in the context of metabolism in highly productive animals. …”
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2815
The Application of Graph Neural Networks in Power Systems from Perspective of Perception-Prediction-Optimization
Published 2024-12-01“…With the increasing uncertainty of the generation, transmission, and consumption sides in new power systems, the complexity and scale of power system topology relationship are continuously growing. …”
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2816
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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2817
The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis
Published 2024-11-01“…Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). …”
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2818
Spatial and Developmental Policy Directions Affecting Marine Spatial Planning in the Northern Aegean Sea, Greece
Published 2024-07-01“…A critical stage of each MSP exercise is the exploration of land- and marine-based policy directions and their current or potential repercussions in the marine environment. …”
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2819
Family Interviews Improve Health Service Recommendations in Mortality Review Process: A Mixed‐Methods Assessment
Published 2025-04-01“…Additionally, US policy leaders in maternal child health and health equity provided historical and current context for FIMR family interview funding and enabling legislation (informing the interpretation of study results and specifically referenced within the manuscript).…”
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2820
A Review of Fish Anomalies in Türkiye’s Waters
Published 2024-10-01“…In the context of this review, 34 articles and symposium proceedings were found to belong to fish anomalies in Türkiye’s waters. …”
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