HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data. by Sára Sáray, Christian A Rössert, Shailesh Appukuttan, Rosanna Migliore, Paola Vitale, Carmen A Lupascu, Luca L Bologna, Werner Van Geit, Armando Romani, Andrew P Davison, Eilif Muller, Tamás F Freund, Szabolcs Káli

“…These models were usually built to capture a few important or interesting properties of the given neuron type, and it is often unknown how they would behave outside their original context. In addition, there is currently no simple way of quantitatively comparing different models regarding how closely they match specific experimental observations. …”
Get full text

Immune factors and their role in tumor aggressiveness in glioblastoma: Atypical cadherin FAT1 as a promising target for combating immune evasion by Manvi Arora, Archismita Kundu, Subrata Sinha, Kunzang Chosdol

“…The FAT atypical cadherin 1 (FAT1) has shown context/tissue-dependent effects in cancers of different tissue origins, with either oncogenic or tumor suppressor roles. …”
Get full text

Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review by Marc Lecoultre, Valérie Dutoit, Paul R Walker

“…In this context, a clear understanding of the impact of TAM phagocytosis on both innate and adaptive immunity is critical. …”
Get full text

Determining the Cost-Effectiveness of Home Care: A Scoping Review by Katerina Gousia, Hansel Teo, Stacey Rand, Florin Vadean

“… Context: The demand for long-term care services provided at home (home care) has increased over time. …”
Get full text

Advancements and Challenges in the Management of Prosthetic Valve Endocarditis: A Review by Francesco Nappi

“…It is a significant concern in the field of cardiology, and the epidemiology of PVE has seen notable developments over the last five decades. The disease currently affects an older demographic and is becoming increasingly prevalent in patients with transcatheter-implanted valves. …”
Get full text

Leveraging agent-based modeling and a randomized intervention to advance childhood physical activity: A study protocol. by Matt Kasman, Adam B Sedlak, Lydia Reader, William J Heerman, Russell R Pate, Amelie G Ramirez, Evan C Sommer, Shari L Barkin, Ross A Hammond

“…The tested ABM will then be used to extrapolate beyond the context of the GROW RCT, experimentally identifying potentially efficacious intervention strategies to improve childhood physical activity through program implementation or changes in policies and practices. …”
Get full text

Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…Consequently, the loofah skeleton and conductive coating were compressed and released simultaneously, effectively functioning as a variable resistor. As applied stress increased, the loofah framework became more compact, gradually increasing the contact area between carbon-based materials of different sizes, thereby generating new current pathways. …”
Get full text

Rational design of 19F NMR labelling sites to probe protein structure and interactions by Julian O. Streit, Sammy H. S. Chan, Saifu Daya, John Christodoulou

“…Here, we exploit the sensitivity of 19F chemical shifts to ring currents by designing labels with direct contact to a native or engineered aromatic ring. …”
Get full text

Pentacene-Based Thin Film Transistor with Inkjet-Printed Nanocomposite High-K Dielectrics by Chao-Te Liu, Wen-Hsi Lee, Jui-Feng Su

“…Finally, we realized top contact pentacene-TFTs and successfully accomplished the purpose of directly patternability and increase the performance of the device based on the nanocomposite by inkjet printing. …”
Get full text

Distribution of urinary neutrophil gelatinase-associated lipocalin and post-translationally modified fetuin-A in outpatients with acute kidney disease detected using a nationwide a... by Ya-Chi Lin, I-Wen Ting, David Ray Chang, Ya-Luan Hsiao, Yu-Ting Lin, Mei-Chuan Hsieh, Shu-Woei Ju, Jie-Sian Wang, Chang-Cheng Jiang, Hsuan-Jen Lin, Cheng-Ting Lu, Che-Chen Lin, Tzu-Ling Tseng, Hung-Chieh Yeh, Hsiu-Yin Chiang, Chin-Chi Kuo

“…Similarly, uPTM-FetA demonstrated comparable characteristics to uNGAL in reflecting kidney injury in the context of AKD.…”
Get full text

Myopia: Mechanisms and Strategies to Slow Down Its Progression by Andrea Russo, Alessandro Boldini, Davide Romano, Giuseppina Mazza, Stefano Bignotti, Francesco Morescalchi, Francesco Semeraro

“…Atropine, orthokeratology/peripheral defocus contact and spectacle lenses, bifocal or progressive addition spectacles, and increased outdoor activities have been associated with the highest, moderate, and lower efficacies, respectively.…”
Get full text

Demographic responses of hybridizing cinquefoils to changing climate in the Colorado Rocky Mountains by Kelly A. Carscadden, Daniel F. Doak, Meagan F. Oldfather, Nancy C. Emery

“…Our findings demonstrate that hybrids in this system are neither intrinsically unfit nor universally more vigorous than parents, suggesting that the demographic consequences of hybridization are context‐dependent. Our results also imply that shifts to warmer and drier conditions could have particularly negative repercussions for P. pulcherrima, which is currently the most abundant taxon in the study area, possibly as a legacy of more favorable historical climates. …”
Get full text

A Transdisciplinary Framework to Bridge Science–Policy–Development Gaps in Global Land Management Initiatives by Nigussie Haregeweyn, Atsushi Tsunekawa, Ayele Almaw Fenta, Pasquale Borrelli, Panos Panagos, Ermias Aynekulu, Takeshi Abe, Peri Pablo, Simon West

“…Over 190 countries (81%) were found to be currently facing moderate or high risk of increased soil erosion from two or more erosion processes, and 182 countries (77%) were found to have a SPDI level that was lower than their soil erosion risk implying the urgent need for a transdisciplinary framework that supports the implementation of future soil erosion research and development projects. …”
Get full text

Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…While habitat composition and planting strategies offer substantial localized benefits, their variability necessitates tailored interventions informed by specific ecological and social contexts. To advance urban carbon neutrality efforts, future research should integrate these findings into practical tools, such as enhanced modules in landscape performance platforms. …”
Get full text

Estimation of wind deflection of high-speed railway catenary based on nonlinear finite element method by CHU Wenping

“…The longitudinal wind deflection affects the current collection quality of the contact wire and the pantograph, and causes contact force fluctuations and pantograph-catenary separation fault. …”
Get full text

Management of food cold chains traceability amid the COVID‑19 pandemic by N. A. Gorbunova, V. N. Kornienko

“…The traceability of temperature fluctuations in meat processing plants is relevant; it becomes an increasingly important factor for efficient logistics to provide the best supply and to keep the food safe in the current conditions. …”
Get full text

A study of conversational agent solution technologies for banana farmer assistance by Luis-Alexander Calvo-Valverde, Kevin Rojas-Salazar, Jose Fabio Hidalgo-Rodríguez, Versalio Mora, Jorge A. Sandoval, Erick Bolaños-Céspedes, Carlos Quirós

“…As an already established technology in the field of customer services, conversational agents can help this solution by covering for experts when users have difficulties contacting them. These artificial agents can answer general queries at any hour, increasing the extension service accessibility. …”
Get full text

To the Discussion on Academic Philosophy: What, How, and What for by Elena A. Guseva, Marina I. Panfilova

“…In the conditions of increasing bureaucratic regulation of the educational process and limited time, it is important to preserve the space of academic freedom, to build teaching taking into account the individual-personal contact with this or that audience. …”
Get full text

The Impact of Low-Level Laser Therapy on Spasticity in Children with Spastic Cerebral Palsy: A Systematic Review by Amalio Jiménez, Frederick R. Carrick, Norman Hoffman, Monèm Jemni

“…Context: Spastic cerebral palsy (SCP) is a condition characterized by muscle stiffness and involuntary movements, which greatly affect movement abilities and overall well-being. …”
Get full text

Rhizosphere Microbiome Diversity Potentially Supports Robust Nature of Field Pennycress (Thlaspi arvense L.) in Dryland Cropping Systems of Eastern Washington by Andrew R. Spishakoff, Pubudu Handakumbura, Chaevien Clendinen, Karen A. Sanguinet, Tarah S. Sullivan

“…ABSTRACT Field pennycress (Thlaspi arvense L.) is an annual in the Brassicaceae family and is currently being developed as an oilseed intermediate crop suitable for renewable biodiesel and jet fuel. …”
Get full text