The role of extracellular vesicles in the diagnosis of glioblastoma progression by A. I. Ryabova, V. A. Novikov, N. V. Yunusova, A. A. Ponomareva, L. V. Spirina, O. V. Gribova

“…Glioblastoma is the most common malignant tumor of the brain characterized by fatal outcome prognosis. Current treatment of tumor recurrence allows to increase patient survival, improve functional outcome and decrease caregivers» load. …”
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Study on Subway Station Street Block-Level Land Use Pattern and Plot Ratio Control Based on Machine Learning by Mingyi Kuang, Fei Fu, Fangzhou Tian, Liwei Lin, Can Du, Yuesong Zhang

“…This study takes Panda Avenue Subway Station as a case study to analyze the evolution of land use patterns around subway stations and explore optimization strategies to enhance land development efficiency and spatial utilizationTo fill this research gap, this paper proposes a CNN-AIMatch model based on machine learning algorithm and an enhanced PLUS-Markov prediction model using the increase and decrease of floor area ratio as a control measure, which adopts an increase in plot ratio as a control measure to improve the accuracy of the Kappa coefficient in different plot ratio scenarios and the prediction of 3D urban spatial growth trends. …”
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The dominant pests (Coleoptera) of cereal crops, and population forecast for this by A. Fedorenko

“…A decrease in the zone of sufficient soil moisture was noted, its line shifted to the north. …”
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Combined effects of conditional cash transfer program and environmental health interventions on diarrhea and malnutrition morbidity in children less than five years of age in Brazi... by Anelise Andrade de Souza, Sueli Aparecida Mingoti, Rômulo Paes-Sousa, Léo Heller

“…The concomitant presence of these measures with environmental sanitation interventions may increase their positive effect. The context of simultaneous improvement of social protection and environmental sanitation is found in Brazil since 2007 and an assessment of the combined effects of both programs has not been performed so far.…”
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Socio-economic problems of hydrogen energy development by M. A. Pletnev, A. N. Kopysov

“…To solve this problem, the method of analyzing the regulatory framework, monographic, scientific and analytical literature, program documents of various levels, real steps of the authorities in the implementation of the fourth energy transition was used. DISCUSSIONS. The current economic model of energy production and consumption is based on an increase in entropy, which leads to irreversible changes in the global ecosystem. …”
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A Hydrological–Energy Balance Model to Assess Land Surface Temperature at the Urban Scale: The Case Study of Milano, Italy by Sonia Morgese, Wenchuang Zhang, Francesca Casale, Daniele Bocchiola

“…Particularly, we showed that an increase of green share, ΔVF = + 10%, may correspond to a decrease of ΔLST = −0.26°C. …”
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FORMATION OF SUSTAINABLE COMPETITIVE ADVANTAGES OF THE EAEU MEMBER STATES IN THE INVESTMENT SPHERE by V. L. Abramov, P. V. Alekseev

“…The analysis shows a decrease in the indicators of economic growth, level of gross accumulation and attracted current and accumulated FDI in the national economies of the overwhelming majority of the EAEU countries, which makes it urgent and necessary to find new methodological and practical approaches to enhancement of the efficiency of integration processes. …”
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Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…Following treatment, the proliferation of leukemic cells was significantly decreased and the apoptosis rate was significantly increased, which was more remarkable for venetoclax. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Motivation to learn German as a foreign language: A systematic literature review by Asuman Yaprak

“…The findings show that motivation studies on German as a foreign language are primarily based on the second language motivational self-system model, the number of studies has increased with the paradigm shift, quantitative research methods and surveys are mainly used as data collection techniques, German is intensively researched together with other languages, and the aim is to determine what increases and decreases motivation by considering motivation levels and factors more.…”
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Stress and influencing factor among children diagnosed with cancer at hospitals in Nepal: a cross-sectional study by Surya Kamal Shahi, Panpan Wang, Jinjin Gu, Rajendra Man Shrestha, Peng Wang

“…The linear regression model showed that stress is associated with socio-demographic variables sex in which female children are more stressed (β = 1.750 (95% CI: 0.46, 3.03) P < 0.05) and clinical features duration of diagnosis as the time increase (12 < Month ≤ 24) level of stress decreased (β =-1.730 (95% CI: -3.20,-0.25) P < 0.05. …”
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Errors in the diagnosis of types of diabetes mellitus: causes and prevention strategies (literature review and own research results) by K.I. Gerush, N.V. Pashkovska, O.Z. Ukrainets

“…This is due to the increasing heterogeneity of DM, blurring of the boundaries between its types, atypical disease course, the decreased diagnostic value of the essential criteria for DM types (age, presence of metabolic syndrome signs, ketosis, dependency on insulin therapy), presence of comorbid conditions, and limited availability of diagnostic tests to specify the type of diabetes. …”
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Application of IVDr NMR spectroscopy to stratify Parkinson’s disease with absolute quantitation of blood serum metabolites and lipoproteins by Georgy Berezhnoy, Gyuntae Bae, Leonie Wüst, Claudia Schulte, Claire Cannet, Isabel Wurster, Milan Zimmermann, Alexander Jäck, Eike Jakob Spruth, Julian Hellmann-Regen, Sandra Roeske, Dominik Pürner, Wenzel Glanz, Fabian Maass, Felix Hufschmidt, Ingo Kilimann, Elisabeth Dinter, Okka Kimmich, Anna Gamez, Johannes Levin, Josef Priller, Oliver Peters, Michael Wagner, Alexander Storch, Paul Lingor, Emrah Düzel, Christoph van Riesen, Ullrich Wüllner, Stefan Teipel, Björn Falkenburger, Mathias Bähr, Inga Zerr, Gabor C. Petzold, Annika Spottke, Patricia Rizzu, Frederic Brosseron, Hartmut Schäfer, Thomas Gasser, Christoph Trautwein

“…Highlights from these comparisons include increased citrate and dimethylglycine with a decrease of creatinine and methionine in healthy controls and early PD group compared to GBA, PD late and recessive PD. …”
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Impact of Sustainable Environmental Expenditures Policy on Air Pollution Reduction, During European Integration Framework by Ionel Bostan, Mihaela Onofrei, Elena-Doina Dascălu, Bogdan Fîrtescu, Carmen Toderascu

“…Pursuant to the growth of society, against the boosting of scientific and technological progress, also arises the negative effect of pollution acceleration. In this context, we relate to risks that imply the growth of pollution, especially against nuisance air pollution increase (CO, SO2, NO etc.) with major implications on the growth of greenhouse effect, the melting of the ice fields, respectively the pollution of the soil with nitrates from fertilizers intensively used in agriculture. …”
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Phenotypic and functional changes of NK cells in patients with myelodysplastic syndrome and acute myeloid leukemia treated with hypomethylating drugs by D. I. Zhigarev, M. V. Khoreva, L. V. Gankovskaya

“…Meanwhile, the origin of this change and its role are important in the context of the disease pathogenesis. Ultimately, a simple description of an increase or decrease in a single receptor expression is not illustrative, since it can lead to uncertain consequences. …”
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Paradigms of the agricultural system in times of COVID-19 by Luis Edgar Blanco-Capia

“…Until the end of the 20th century, world agriculture underwent a transition towards a new technological paradigm, very different from that of the green revolution, based on the current “bio” revolutions, in which human beings have transformed biodiversity by placing it at their service1. …”
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INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW) by L.V. Smaglyuk, H.V. Voronkova, A.Ye. Karasiunok, A.V. Liakhovska, V.I. Smaglyuk

“…Over the last decade, there has been a clear trend towards an increase in the prevalence of malocclusion, which reaches 80% according to current scientific literature and sometimes it exceeds this percentage. …”
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Comparative legal analysis of the labor law status of a higher school lecturer by T. F. Vysheslavova, S. A. Lukinova

“…The authors analyze the provisions of the current Russian labor legislation on the work of higher education lecturers in the context of globalization and the intensification of the global financial and economic crisis. …”
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Philosophy of School Multilingualism in the Era of Political Multiculturalism. French Experience. Case of France by N. V. Litvak

“…In France, the hours devoted primarily to mathematics are constantly decreasing for this. But fewer and fewer children are able to cope with such a “lightweight” and “interesting” program, and for many years there has been a decline in the level of general education. …”
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Investigating the Relationship between Types of Deprivation and Social Tolerance among Citizens of Tehran by Negar Firouzeh, Khadijeh Safiri

“…Specifically, as these forms of deprivation increased (excluding political deprivation), social tolerance tended to decrease. …”
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