Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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Strategies for adaptation of Russian commercial banks to innovative technologies by O. S. Solenaya

“…All banking innovations have a significant impact on the current business models of commercial banks, increasing the efficiency of their activities and at the same time the level of competition both in the banking sector and in the financial markets as a whole…”
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Motivation to learn German as a foreign language: A systematic literature review by Asuman Yaprak

“…The findings show that motivation studies on German as a foreign language are primarily based on the second language motivational self-system model, the number of studies has increased with the paradigm shift, quantitative research methods and surveys are mainly used as data collection techniques, German is intensively researched together with other languages, and the aim is to determine what increases and decreases motivation by considering motivation levels and factors more.…”
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Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…Following treatment, the proliferation of leukemic cells was significantly decreased and the apoptosis rate was significantly increased, which was more remarkable for venetoclax. …”
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Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units by Anna Rymkiewicz

“…The percentage of those able to cope with complex mental tasks has decreased significantly, the percentage of nurses who are overburdened with too many tasks has increased, 75% of them notice the impact of work on family life. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Climate Change Risk, Performance, and Value Added in Agricultural Sector by Ramin Amani, Zanko Ghorbani, Zana Mozaffari

“…This, in turn, results in decreased production costs, increased investment returns, surplus domestic supply, and expanded agricultural product exports. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies by O. B. Gordeeva, M. S. Karaseva, D. E. Lavretsky, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, G. V. Revunenkov, E. A. Abashidze, M. V. Egorova

“…Thrombosis in children with genetically determined thrombophilia often occur in the context of risk factors. In the early neonatal period, the deficiency of anticoagulant factors manifests as the form of fulminant purpura, followed by the development of skin necrosis. …”
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Quinoa in Peru: Andean Pseudocereal, a food for present and future generations by Jesús De La Cruz-Arango

“…This is especially important in the current context, and it is necessary to take measures to adapt to climate change7. …”
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A Sociological study of the Relationship between Smartphone Addiction and Phubbing Case Study18-29 Year Old Females of Ramhormoz City by Ali Boudaghi, Ali Hossein Hosseinzadeh, Sayedeh Sara Mousavi Moghadam

“…In recent years, along with the digital transition and the increase of smart phone users, phubbing, as an emerging phenomenon, has drawn the attention of scholars and experts. …”
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Application of IVDr NMR spectroscopy to stratify Parkinson’s disease with absolute quantitation of blood serum metabolites and lipoproteins by Georgy Berezhnoy, Gyuntae Bae, Leonie Wüst, Claudia Schulte, Claire Cannet, Isabel Wurster, Milan Zimmermann, Alexander Jäck, Eike Jakob Spruth, Julian Hellmann-Regen, Sandra Roeske, Dominik Pürner, Wenzel Glanz, Fabian Maass, Felix Hufschmidt, Ingo Kilimann, Elisabeth Dinter, Okka Kimmich, Anna Gamez, Johannes Levin, Josef Priller, Oliver Peters, Michael Wagner, Alexander Storch, Paul Lingor, Emrah Düzel, Christoph van Riesen, Ullrich Wüllner, Stefan Teipel, Björn Falkenburger, Mathias Bähr, Inga Zerr, Gabor C. Petzold, Annika Spottke, Patricia Rizzu, Frederic Brosseron, Hartmut Schäfer, Thomas Gasser, Christoph Trautwein

“…Highlights from these comparisons include increased citrate and dimethylglycine with a decrease of creatinine and methionine in healthy controls and early PD group compared to GBA, PD late and recessive PD. …”
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From Imbalance to Synergy: The Coupling Coordination of Digital Inclusive Finance and Urban Ecological Resilience in the Yangtze River Economic Belt by Xi Chen, Xuan Huang, Tonghui Yu, Yu Zhang, Xufeng Cui

“…The results show that (1) The CCD between DIF and UER in the YREB has increased annually from 2011 to 2020. However, there are persistent imbalances, with an overall low level of coordination and uneven spatial development, and a trend of “higher coordination in the east and lower coordination in the west”. (2) The overall CCD of the YREB has reached at least the primary coordination level, with the coupling enhancement speed ranked as “downstream > midstream > upstream”, and regional differences decreasing. (3) The decoupling analysis reveals a predominant decoupling trend between DIF and UER, indicating that the digitization of financial services has not concurrently increased ecological pressures. (4) The obstacle degree analysis identifies resilience and digitalization as major barriers hindering CCD. …”
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Climate and human activities alter coupling of soil macro- and micronutrients: Evidence from a long-term experiment in typical steppes by Yi Zhou, Shenghua Chang, Xiaojuan Huang, Wenjun Wang, Fujiang Hou, Yanrong Wang, Zhibiao Nan

“…Our results showed decreases in soil Zn and Fe stocks, alongside increases in Cu, SOC, and STN stocks over time. …”
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Philosophy of School Multilingualism in the Era of Political Multiculturalism. French Experience. Case of France by N. V. Litvak

“…In France, the hours devoted primarily to mathematics are constantly decreasing for this. But fewer and fewer children are able to cope with such a “lightweight” and “interesting” program, and for many years there has been a decline in the level of general education. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC by O. A. Tettsoeva

“…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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