Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Compost from the food waste for organic production of cabbage, cauliflower, and radish under sub-tropical conditions by Neha Kumari, Anit Sharma, Mamta Devi, Atif Zargar, Sunny Kumar, Umesh Thakur, Ajay Bhatia, Khushboo Badhan, Sunaina Chandel, Arpana Devi, Kriti Sharma, Shweta Kumari, Mussarat Choudhary, Arup Giri

“…The application of compost increased leaf relative water content and decreased the electrolyte leakage in all the plants. …”
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The impacts of climate variability on conflict risk in conflict-prone regions worldwide by Xiaolan Xie, Fangyu Ding, Mengmeng Hao, Jun Zhuo, Shuai Chen, Jiajie Wu, Jiping Dong, Kai Sun, Qian Wang, Dong Jiang

“…The meta-analysis shows that one standard positive temperature deviation (1σ), increased extreme precipitation, and decreased precipitation induce 0.81 %, 2.53 %, and 1.04 % increment respectively in the risk of conflict incidence, as well as 1.12 %, 2.55 %, and 1.15 % decrement respectively in the risk of conflict onset. …”
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Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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From Imbalance to Synergy: The Coupling Coordination of Digital Inclusive Finance and Urban Ecological Resilience in the Yangtze River Economic Belt by Xi Chen, Xuan Huang, Tonghui Yu, Yu Zhang, Xufeng Cui

“…The results show that (1) The CCD between DIF and UER in the YREB has increased annually from 2011 to 2020. However, there are persistent imbalances, with an overall low level of coordination and uneven spatial development, and a trend of “higher coordination in the east and lower coordination in the west”. (2) The overall CCD of the YREB has reached at least the primary coordination level, with the coupling enhancement speed ranked as “downstream > midstream > upstream”, and regional differences decreasing. (3) The decoupling analysis reveals a predominant decoupling trend between DIF and UER, indicating that the digitization of financial services has not concurrently increased ecological pressures. (4) The obstacle degree analysis identifies resilience and digitalization as major barriers hindering CCD. …”
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Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
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Credit Rationing Equilibrium Achievement in the Conditions of Digitalization by O. V. Lunyakov

“…The authors’ hypothesis is that the credit market has the potential to increase the return on a loan per currency unit of borrowers’ loans, and the current estimates of the of defaults borrowers’ probability, interest rates are “biased”. …”
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USE OF AGRICULTURAL POTENTIAL FOR ECONOMIC RECOVERY/GROWTH by Ana-Maria IFRIM, Marius-Mihai MICU, Oana-Raluca RUSU, Catalin Ionut SILVESTRU, Cristina Vasilica ICOCIU

“…In the current context, after a pandemic that has left traces in all socio-economic fields and during major geo-political problems, Basic research is needed in order to identify directions for rapid and sustainable socio-economic recovery. …”
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Revealing the Hidden Benefits of Dust for Photovoltaic Performance in Hot Climates by Omar A. Abdulrazzaq, Sura N. Atewi, Raghad A. Tuama, Akram K. Hasan, Muatez Mohammed

“…The results reveal that temperature predominantly reduces voltage, while dust primarily diminishes current. However, during dust storms, temperatures significantly drop below their average, potentially leading to an increase in PV output. …”
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Philosophy of School Multilingualism in the Era of Political Multiculturalism. French Experience. Case of France by N. V. Litvak

“…Further research is needed, as well as the study of potential and latent risks of the current educational policy.…”
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Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units by Anna Rymkiewicz

“…The percentage of those able to cope with complex mental tasks has decreased significantly, the percentage of nurses who are overburdened with too many tasks has increased, 75% of them notice the impact of work on family life. …”
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Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…Following treatment, the proliferation of leukemic cells was significantly decreased and the apoptosis rate was significantly increased, which was more remarkable for venetoclax. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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TRENDS REGARDING DEVELOPMENT THE SUSTAINABLE WINE TOURISM IN THE REPUBLIC OF MOLDOVA by Viorica GUȚAN, Constanta Laura ZUGRAVU, Maria Magdalena TUREK RAHOVEANU, Gheorghe Adrian ZUGRAVU

“…In this context, the purpose of the paper is to identify and analyze the current trends and developments in the wine tourism sector in Moldova, focusing on sustainable practices. …”
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Characterizing dengue transmission in rural areas: A systematic review. by Olivia Man, Alicia Kraay, Ruth Thomas, James Trostle, Gwenyth O Lee, Charlotte Robbins, Amy C Morrison, Josefina Coloma, Joseph N S Eisenberg

“…In some rural areas, the force of infection appears to be increasing over time, as measured by increasing seroprevalence in children and thus likely decreasing age of first infection, suggesting that rural dengue transmission may be a relatively recent phenomenon. …”
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Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies by O. B. Gordeeva, M. S. Karaseva, D. E. Lavretsky, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, G. V. Revunenkov, E. A. Abashidze, M. V. Egorova

“…Thrombosis in children with genetically determined thrombophilia often occur in the context of risk factors. In the early neonatal period, the deficiency of anticoagulant factors manifests as the form of fulminant purpura, followed by the development of skin necrosis. …”
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Effectiveness of Nursing Intervention Protocol on Nurses’ Performance and Patients’ Self-Care after Cataract Surgery by Amal S. Taha

“… Context: Cataract is the leading cause of poor vision worldwide. …”
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Attention as a commodity in the world of disinformation and social media by Radoslav Ivančík, Pavel Nečas, Lucia Iľaščíková

“…Unfortunately, in many cases, it is also through the spread of disinformation. In this context, the authors, using relevant methods of scientific research, focused on attention as a commodity and the functioning of the attention economy in the context of the increasing extent of the spread of various disinformation (but also hoaxes and conspiracy theories) primarily through social networks, their susceptibility to the spread of unwanted content and efforts to regulate the spread of such content.…”
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