Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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Designing an entrepreneurial ecosystem model in a university with a knowledge-based approach by Nahid Mir, Amin Rahimi Kia, Mehry Daraei

“…AbstractThe aim of the current research is to Designing an entrepreneurial ecosystem model in the university with a knowledge-oriented approach. …”
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Advances in Encapsulating Marine Bioactive Compounds Using Nanostructured Lipid Carriers (NLCs) and Solid Lipid Nanoparticles (SLNs) for Health Applications by Rita Favas, Hugo Almeida, Andreia F. Peixoto, Domingos Ferreira, Ana C. Silva

“…As life expectancy rises and modern lifestyles improve, there is an increasing focus on health, disease prevention, and enhancing physical appearance. …”
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Adolescents’ exposure to explicit sexual content on digital media: a quantitative, cross-sectional study by Semen Sebsbie, Anteneh Tsegaye

“…Although adolescents’ screen media use has been broadly studied, little attention has been paid to the consumption of sexually explicit screen media content, especially in low- and middle-income contexts where access to digital media technologies is increasing. …”
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Deterioration of sleep and mental health in individuals with insomnia during South Africa’s COVID-19 lockdown by Alison Bentley, Laura C. Roden, Jonathan P. Davy, Stella Iacovides, F. Xavier Gómez-Olivé, Karine Scheuermaier, Raphaella Lewis, Gosia Lipinska, Johanna Roche, Candice J. Christie, Swantje Wells, Dale E. Rae

“…Comparative analyses were conducted between participants who identified a current or previous diagnosis of insomnia (n = 135, Insomnia group, irrespective of whether they had current symptoms or not) and those reporting no sleep disorders (n = 700, No-Insomnia group). …”
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Enhancing Smart Cities with IoT and Cloud Computing: A Study on Integrating Wireless Ad Hoc Networks for Efficient Communication by Haider Mohammed Abdulhadi, Yousra Abdul Alsahib S. Aldeen, Maryam A. Yousif, Mays jalal jaseem, Syed Hamid Hussain Madni

“…IoT data is first collected in the context of smart cities. The data that is gathered is uniform. …”
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Key Barriers to Personalized Learning in Times of Artificial Intelligence: A Literature Review by Gina Paola Barrera Castro, Andrés Chiappe, María Soledad Ramírez-Montoya, Carolina Alcántar Nieblas

“…Personalized learning (PL) has emerged as a promising approach to address diverse educational needs, with artificial intelligence (AI) playing an increasingly pivotal role in its implementation. This systematic literature review examines the landscape of PL across various educational contexts, focusing on the use of AI and associated challenges. …”
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The Impact of Low-Level Laser Therapy on Spasticity in Children with Spastic Cerebral Palsy: A Systematic Review by Amalio Jiménez, Frederick R. Carrick, Norman Hoffman, Monèm Jemni

“…Context: Spastic cerebral palsy (SCP) is a condition characterized by muscle stiffness and involuntary movements, which greatly affect movement abilities and overall well-being. …”
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The challenges of reproducibility for research based on geodata web services by M. Cannata, M. Collombin, O. Ertz, G. Giuliani, J. Ingensand, C. Primerano, D. Strigaro

“…Additionally, we assess the currently available tools that support data versioning for databases, files and log-structured tables. …”
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Lipidomic markers of obesity and their dynamics after bariatric surgery by T. V. Saprina, A. S. Bashirova, V. V. Ivanov, S. I. Pekov, I. A. Popov, S. R. Bashirov, E. A. Vasilyeva, O. A. Pavlenko, D. V. Krinitskii, M. Chen

“…Currently available studies and their results suggest that we are only at the very start of studying this promising biomedical field.…”
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Physicians’ experiences of assessing and supporting fatigued patients in primary care: a focus group study by Conrad Samuelsson, Lisa Gunnarsson, Frank Svärdman, Christian Rück, Elin Lindsäter

“…Abstract Background Fatigue is a common symptom in primary healthcare, affecting 10–30% of patients, and is associated with increased healthcare consumption and functional disability. …”
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Innovative Thermosensitive Composite Materials: Merging Poloxamer PF‐127 and Polysaccharides for Enhanced Functional Properties by Marcos Blanco‐López, Inmaculada deDios‐Pérez, Álvaro González‐Garcinuño, Antonio Tabernero, Eva Martín del Valle

“…Abstract Currently, new cancer treatment options are being developed following tumor resection surgery, with a focus on minimizing invasiveness and reducing systemic toxicity to lower the risk of recurrence. …”
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Assessing coupled human-flood interactions using LiDAR geostatistics and neighbourhood analyses by Morgan J. Breen, Abiy S. Kebede, Carola S. König

“…The paper integrates well-established methods from other spheres of flood risk assessment in a novel way to explore the currently poorly understood Safe Development Paradox (SDP) phenomenon in coastal settings. …”
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A Methodological Proposal for Determining Environmental Risk Within Territorial Transformation Processes by Marco Locurcio, Felicia Di Liddo, Pierluigi Morano, Francesco Tajani, Laura Tatulli

“…The built assets and the real estate sector play a key role in this context; indeed, being among the first ones to be exposed to the effects of climate change, they serve as a crucial tool for the implementation of governance strategies that are more focused on environmental issues. …”
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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Participants Participants had current low back pain without indicators of serious spinal pathology. …”
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A guide to evade hallucinations and maintain reliability when using large language models for medical research: a narrative review by Sangzin Ahn

“…Large language models (LLMs) are increasingly prevalent in medical research; however, fundamental limitations in their architecture create inherent reliability challenges, particularly in specialized medical contexts. …”
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Being there but where? Sense of presence theory for virtual reality applications by Stefano Triberti, Caterina Sapone, Giuseppe Riva

“…As immersive technologies become increasingly prevalent in shared environments and sensitive contexts such as education and healthcare, this more sophisticated understanding of presence becomes crucial for designing effective virtual experiences. …”
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The Impact of brain-gut microbiota composition on depression by Aleksander Ptasiński, Marta Targońska, Oskar Targoński, Adrianna Madej, Adrian Suława, Julia Furgalska, Sebastian Fedorowicz, Aneta Basiak, Rafał Niekurzak, Agnieszka Buczek

“…It is important to note the significant individual variability in the context of changes in the depressive microbiome and the response to various modification methods. …”
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Analysis of Factors Influencing Millennial Consumers' Decision in Buying Halal Cosmetics by Novalini Jailani, Susminingsih, Hendri Hermawan Adinugraha, Fatimah Kari, Adib Muhammad

“… The market potential of the halal cosmetics is currently very promising and the use of cosmetics among millennials is increasing. …”
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Replacing penalties by V. Stepashin

“…It is important in the context of the topic and the possibility of a sentence of imprisonment as a substitute punishment in cases where the original purpose of the strict measures excluded. …”
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