Quantitative systems toxicology modeling in pharmaceutical research and development: An industry‐wide survey and selected case study examples by Kylie A. Beattie, Meghna Verma, Richard J. Brennan, Diana Clausznitzer, Valeriu Damian, Derek Leishman, Mary E. Spilker, Britton Boras, Zhenhong Li, Elias Oziolor, Theodore R. Rieger, Anna Sher

“…Abstract Quantitative systems toxicology (QST) models are increasingly being applied for predicting and understanding toxicity liabilities in pharmaceutical research and development. …”
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Factors that influence anemia prevalence: a comparative study of datasets from Russia and South Africa by Maria A. Burilina, Natisha Dukhi, Aleksandra L. Mashkova, Ivan V. Nevolin, Ronel Sewpaul

“…Conclusions The comparison of socio-economic factors influencing the prevalence of anemia between Russian and South African samples has validated self-assessments as a reliable proxy for health status in the context of Russia. This methodological advancement underpins current and future research based on the extensive database of the Russia Longitudinal Monitoring Survey, encompassing approximately 2,500 indicators, to investigate disease prevalence.…”
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Study of Radon Radiation in the Area of the Akchatau Polymetallic Mine, Republic of Kazakhstan by Yuriy Pak, Dmitriy Pak, Vladimir Matonin, Diana Ibragimova, Pavel Timoshenko, Yuriy Barkov, Anar Tebayeva, Pavel Medvedev

“…Increased radon concentration in a number of areas is associated with the Akchatau tungsten–molybdenum mine. …”
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The global energy challenge: second-generation feedstocks on marginal lands for a sustainable biofuel production by Claudio Russo, Valerio Cirillo, Nausicaa Pollaro, Fabio Terribile, Andrea Chiodini, Albino Maggio

“…Biofuels represent a renewable source of energy, but their production has raised concerns regarding their possible impacts on food security. Indeed, the current biofuel production primarily relies on food crops and arable lands. …”
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The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs by Ana Luísa Garcia-Oliveira, Rodomiro Ortiz, Fatma Sarsu, Søren K. Rasmussen, Paterne Agre, Asrat Asfaw, Moctar Kante, Subhash Chander

“…In this context, transforming food systems go far beyond just farmers and plant breeders and it requires substantial contributions from industry, global finances, transportation, energy, education, and country developmental sectors including legislators. …”
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Energy recovery analysis through numerical simulations of steam injection in continental shale oil reservoirs by Maryelin Josefina Briceño Montilla, Shouding Li, Zhaobin Zhang, Yanzhi Hu, Jianming He, Zheng Bo, Xiao Li

“…However, optimizing energy utilization to maximize hydrocarbon production remains a significant challenge, particularly in the context of current energy limitations. This study compares two steam injection strategies using a thermal-flow-chemical (TFC) simulator to assess energy recovery efficiency. …”
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Precision livestock farming in buffalo species: a sustainable approach for the future by Roberta Matera, Federica Pierro, Matteo Santinello, Antonio Iraci Fuintino, Giovanmaria Pacelli, Tomas Norton, Gianluca Neglia

“…The increasing global demand for animal-derived foods in a climate-changing context requires innovative strategies to enhance farm efficiency and sustainability. …”
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Unravelling the myriad physiologic roles of transthyretin: critical considerations for treating transthyretin amyloidosis by Morie A. Gertz, Mandar A. Aras, Nicole Bart, Thomas H. Brannagan, Jan M. Griffin, Amy R. Kontorovich, Andrew M. Rosen

“…While a link between low TTR and severe disease and mortality is well established, it remains unclear whether long-term TTR suppression via ATTR therapies increases risk of disease. Clinical decisions in ATTR, however, should reflect the current understanding of the roles of TTR and the patient’s clinical history.Conclusion TTR serves vital physiologic roles across organ systems. …”
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Valuation of informal care for the old-aged with disabilities in China—a discrete choice experiment approach by Zhan Zhao, Shuaizhen Chen, Fengyi Sun, Wenjing Cheng, Chen Chen, Elizabeth Maitland, Stephen Nicholas, Jian Wang, Lei Si, Jialong Tan

“…The probability of choosing cash compensation rose when compensation increased and fells when the care time increased. The preferences for assistance varied significantly by individual’s demographic and health-related characteristics. …”
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Advances in Oncolytic Viral Therapy in Melanoma: A Comprehensive Review by Ayushi Garg, Rohit Rao, Felicia Tejawinata, Gazi Amena Noor Shamita, McKay S. Herpel, Akihiro Yoshida, Gordon Goolamier, Jessica Sidiropoulos, Iris Y. Sheng, Salim-Tamuz Abboud, Luke D. Rothermel, Nami Azar, Ankit Mangla

“…From the historical use of wild viruses to the sophisticated use of genetically modified viruses in the current era, oncolytic virus therapy has evolved tremendously in the last two decades. …”
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Trend-Enabled Recommender System with Diversity Enhancer for Crop Recommendation by Iulia Baraian, Rudolf Erdei, Rares Tamaian, Daniela Delinschi, Emil Marian Pasca, Oliviu Matei

“…However, the applicability of many current systems is limited by their considerable computational requirements and dependence on comprehensive datasets, especially in resource-limited contexts. …”
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Walking apps for active aging? A literature and multi-source review of their impact on older adult users’ mobility and wellbeing by Pau Llopis, Oscar Oviedo-Trespalacios, Francisco Alonso, Mireia Faus, Sergio A. Useche

“…In the coming decades, many countries are expected to experience a marked increase in the average age of their populations, raising new challenges for healthcare and mobility systems. …”
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Experiential learning for societal impact by Elizabeth A. McCrea, Dilip Mirchandani

“…Purpose – This paper examines how business schools can respond to calls to increase their impact by effectively leveraging experiential learning approaches that address complex societal issues. …”
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The Essence and Content of Product Distribution as an Economic Category by Viktoriia Bozhkova, Mykhailo Bilukha

“…Thus, the study made it possible to systematize current approaches to defining distribution in terms of chronology and three-component structure (essence, content and result of the phenomenon), which served as the basis for the author's definition. …”
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Urban human-elephant conflict in Zimbabwe: a case study of the mitigation endeavour by Aliénor Scrizzi, Sébastien Le Bel, Mike La Grange, Daniel Cornélis, Cheryl Mabika, René Czudek

“…In this context, human-elephant interactions are expected to increase. …”
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Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions by Nurlan Zhangabay, Aizhan Zhangabay, Kenzhebek Akmalaiuly, Akmaral Utelbayeva, Bolat Duissenbekov

“…This area is becoming particularly relevant in the context of global challenges related to climate change, rising energy costs and increased environmental requirements. …”
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Sarcopenia in Rheumatic Diseases: A Hidden Issue of Concern by Eleni C. Pardali, Markos Klonizakis, Dimitrios G. Goulis, Sousana K. Papadopoulou, Christos Cholevas, Constantinos Giaginis, Christina Tsigalou, Dimitrios P. Bogdanos, Maria G. Grammatikopoulou

“…The present narrative review seeks to explore the methods used to assess sarcopenia in patients with RDs, its prevalence among them, and the challenges faced by the affected individuals, while critically assessing the appropriateness and limitations of current sarcopenia assessment tools in the context of RDs.…”
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THE ANALOGY OF STATUTE AND THE ANALOGY OF LAW AS DOCTRINAL INSTRUMENTS FOR LEGAL RESPONSE TO ECONOMIC CHALLENGES by Serhii Zavalniuk, Volodymyr Zavalniuk, Iryna Zavalniuk

“…The analogy of statute (analogy legis) and the analogy of law (analogy iuris) hold a distinct place among the tools for overcoming legal gaps in the economic sphere. In the context of the global trend of expanding the scope of judicial discretion, the question of the admissibility and methodology of analogies is becoming increasingly critical. …”
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Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia by Ilinca Untu, Michael Davidson, Gabriela-Dumitrita Stanciu, Jonathan Rabinowitz, Jonathan Rabinowitz, Romeo-Petru Dobrin, Diana-Sabina Vieru, Bogdan-Ionel Tamba, Bogdan-Ionel Tamba

“…These mechanisms likely contribute to the acceleration of neurodegeneration in AD and the onset or worsening of depressive symptoms. Current therapeutic approaches remain largely nonspecific, with a lack of targeted therapies that address the unique pathophysiological context of depression in AD. …”
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Emergency response mobile 3D printing system: A case study in rapid manufacturing of polyurethane foam bridges by Jingwen Liang, Zhuo Zeng, Penglin Wang, Zhongxu Wang, Shifeng Wen, Yan Zhou, Cheng Zhou

“…In the context of increasing global natural disasters, the 72-hour golden rescue window imposes three critical requirements on rapid construction technologies: timeliness, multi-hazard adaptability, and systemic support. …”
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