Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity. by Elizaveta Katorcha, Natallia Makarava, Regina Savtchenko, Alessandra D'Azzo, Ilia V Baskakov

“…The current study demonstrates that undersialylated PrP(C) is selected during prion amplification in Protein Misfolding Cyclic Amplification (PMCAb) at the expense of oversialylated PrP(C). …”
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Wisdom of the Established Pattern by Joel Janhonen

“…According to their example, if someone is opposed to increasing as well as decreasing the average human intelligence, they need a good reason for why the current level is optimal. …”
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Performance assessment of a novel design of double slope solar: Energy and water quality analysis by Sabir Widatalla, Hassan Mohammed, I.B. Sapaev, Ramachandran T, John William Grimaldo Guerrero, Aman Shankhyan, P Vijaya Kumar, Vikasdeep Singh Mann, Hossein Sharif

“…A further increase in temperature from 80°C to 90°C leads to a 141% increase in water production under the same wind conditions.…”
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Medical triage as an AI ethics benchmark by Nathalie Maria Kirch, Konstantin Hebenstreit, Matthias Samwald

“…Adversarial prompts significantly decreased accuracy. By demonstrating the influence of context and ethical framing on the performance of LLMs, we provide critical insights into the current capabilities and limitations of AI in high-stakes ethical decision making in medicine.…”
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ANALYSIS OF THE DYNAMICS AND TRENDS IN THE DEVELOPMENT OF MODERN INTERNATIONAL TOURIST MARKET by J. A. Pshenichnyh

“…Based on the statistical data of international organizations, the author studied indicators of international tourist flows, identified the main trends in the development of international tourism at the current stage, assessed the impact on the tourism sector of the COVID-19 pandemic and determined possibilities for its development in the context of the economic crisis, showed prospects for the development of the industry.…”
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The state and prospects of the development of small and medium business in the conditions of war in Ukraine by Viktoriia M. Orlova, Olena R. Serhieieva, Oksana V. Kuzmenko

“…This paper investigates the current state of small and medium business in Ukraine. …”
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Forest stand biomass of Picea spp.: an additive model that may be related to climate and civilisational changes by Usoltsev Vladimir А., Piernik Agnieszka, Osmirko Anna A., Tsepordey Ivan S., Chasovskikh Viktor P., Zukow Walery

“…Since ancient times, climate change has largely determined the fate of human civilisation, which was related mainly to changes in the structure and habitats of forest cover. In the context of current climate change, one must know the capabilities of forests to stabilise the climate by increasing biomass and carbon-depositing abilities. …”
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Symptom palliation in patients with bone metastases treated with radiotherapy by Kartick Rastogi, Shivani Gupta, Sandeep Bhaskar, Aseem-Rai Bhatnagar, Subhash-Chand Bairwa, Sandeep Jain

“…The 8 Gy single-fraction schedule was associated with maximum relief in insomnia and decrease in analgesic requirement. Conclusion: The current institutional protocol of weekly hypofractionated palliative RT of 6.25 Gy per fraction up to a maximum of four fractions given on Saturday has shown results comparable with other schedules with well tolerance and achievement of acceptable symptom palliation. …”
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The Impact of Fiscal Sovereignty in the Field of Real Estate Tax on Municipal Revenues by Patrycja Świerczek-Dutka

“…Findings: The analysis indicated that from 2018 to 2023 the exercise of fiscal sovereignty by municipalities resulted in a total revenue decrease of PLN 20.2 billion (13% of total real estate tax revenue during this period). …”
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Towards the New World Order: Theoretical Interpretations and Practical Implementations by K. A. Efremova

“…Followers of the fatalist approach (neo-realists, globalists) believe that world order is a zero-sum game, where interstate interactions are mostly confrontational, and their pattern depends on the current balance of power. Mitigators (neo-liberals, functionalists, constructivists, etc.) insist that the emerging world order is a win-win game, where nations opt for investing some of their sovereignty into newly created international institutions (regimes and organizations), hoping that conventional rules adopted by them would help to decrease international uncertainty, which otherwise might lead to confrontation. …”
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Spatial Decision Support System for Efficient School Location-Allocation by Marios Batsaris, Dimitris Kavroudakis, Euripides Hatjiparaskevas, Panagiotis Agourogiannis

“…The results indicate a decrease of 8% in total distance whereas proximity and capacity constraints were respected accordingly. …”
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The Palliative Care in Patients with Oncological Diseases - a New Medical and Therapeutic Approach by Catalina FLORESCU, Octavian VASILIU, Dan PRELIPCEANU

“…The severity of pain, the intensity of depression, and anxiety in family members decreased significantly during six months of the standard-of-care psychotropic medication administered for depressive disorders. …”
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The essence and features of the regulatory framework of the National Police of Ukraine by V. B. Pchelin, V. Y. Kikinchuk

“…It has been determined that the structural components of the National Police of Ukraine regulated by the current national legislation do not cover all areas of functioning of this central executive body. …”
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MicroRNA as a Potential Biomarker for Amyotrophic Lateral Sclerosis (ALS) by José Augusto Nogueira-Machado, Amanda Tábita da Silva Albanaz, Fabiana Rocha-Silva

“…<b>Aim</b>: This review analyzes dysregulated microRNA signaling pathways and their interactions with metabolic pathways in the context of ALS progression. <b>Significance:</b> Despite this, biomarkers remain unreliable, and the current medications prolong life without providing a cure. …”
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The Relationship between the Tenure of an Audit Firm Partner and Audit Quality: Examining the Moderating Role of Audit Firm Change by MohammadReza Haghdadi, Mansour Garkaz, Alireza Moetoofi

“…The research aims to explore this relationship while examining the moderating role of switching audit firms.MethodsThe current research was conducted within the unique context of Iran, focusing on evaluating the turnover of audit firm partners. …”
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Sustainable agricultural mechanization in Timor-Leste: status, challenges and further action by Jelle Van Loon, Mayling Flores Rojas

“…Beyond this, a reform of the current government mechanization hire schemes is needed: integrated approaches, as found from business model analyses and training exercises during field missions, are needed, that entail context-specific solutions for targeted rural communities, with special attention given to participatory extension, inclusive co-validation of technologies, and private sector-led business model development around mechanization service delivery. …”
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Exploring the Impression of Irrigation Management Techniques on Crop Harvests and Water Habit Efficiency by Hussein Layth, Ramadan Ghazi Mohamad, Prakash Akula

“…The future scheme contains the enactment of a WUE procedure to estimate and associate the presentation of these irrigation methods. …”
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Early Detection of the Marathon Wall to Improve Pacing Strategies in Recreational Marathoners by Mohamad-Medhi El Dandachi, Veronique Billat, Florent Palacin, Vincent Vigneron

“…The individual marathon optimal pacing sparring the runner to hit the “wall” after 2 h of running remain unclear. In the current study we examined to what extent Deep neural Network contributes to identify the individual optimal pacing training a Variational Auto Encoder (VAE) with a small dataset of nine runners. …”
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MXene-Assisted Enhanced Electrochemical Performance of Doped Strontium Titanium Nanoparticles by Muhammad Qaiser Manzoor, Syed Irfan, null Anwar-ul-Haq, Xuyang Shi

“…The value of specific capacitance for the hybrid tested via galvanostatic charge-discharge showed an increased value of 23 Fg‒1 at the current density of 1 Ag-1. …”
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Impact of Majorana fermions on the Kondo state in the carbon nanotube quantum dot by D Krychowski

“…Furthermore, we have shown that the device coupled with three Majorana fermions (3TSC) achieves a quantized conductance 5/2( e ^2 / h ), preserves the U ^⋆ (1) charge symmetry at the electron-hole symmetry point and manifests the increase in nonlinear current and shot noise due to the entanglement in octuplets with opposite charge-leaking states.…”
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