Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China by Ziyang Liu, Davide Cammarano, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…The number of days in the growth period during the sowing-to-jointing stage and jointing-to-flowering stage decreased significantly, the number of days during the flowering-to-maturity stage increased significantly. …”
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Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH). by Jessica Min-DeBartolo, Franklin Schlerman, Sandeep Akare, Ju Wang, James McMahon, Yutian Zhan, Jameel Syed, Wen He, Baohong Zhang, Robert V Martinez

“…Activation of PPARα pathway was supported by observed decrease in serum lipid levels. Our findings provide important insights into the role of TSP-1 in context of NAFLD/NASH and TSP-1 may be a target of interest to develop anti-fibrotic therapeutics for NAFLD/NASH.…”
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Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings by Sophie Guerin, Christian Bieli, Regula Corbelli, Thomas Ferry, Miriam Giaranna, Matthias Horn, Silvia Miano, Nicolas Regamey, Daniel Trachsel, Sylvain Blanchon

“…Analysis of the first year’s data in the SwissPedHRS registry showed a sixfold increase in prevalence since 2001. It also highlighted a larger spectrum of underlying medical conditions and types of sleep-disordered breathing leading to home respiratory support and important changes in home respiratory support modalities, with decreased invasive and increased non-invasive respiratory support and decreased BPAP and increased CPAP ventilation. …”
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The role of extracellular vesicles in the diagnosis of glioblastoma progression by A. I. Ryabova, V. A. Novikov, N. V. Yunusova, A. A. Ponomareva, L. V. Spirina, O. V. Gribova

“…Glioblastoma is the most common malignant tumor of the brain characterized by fatal outcome prognosis. Current treatment of tumor recurrence allows to increase patient survival, improve functional outcome and decrease caregivers» load. …”
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Combined effects of conditional cash transfer program and environmental health interventions on diarrhea and malnutrition morbidity in children less than five years of age in Brazi... by Anelise Andrade de Souza, Sueli Aparecida Mingoti, Rômulo Paes-Sousa, Léo Heller

“…The concomitant presence of these measures with environmental sanitation interventions may increase their positive effect. The context of simultaneous improvement of social protection and environmental sanitation is found in Brazil since 2007 and an assessment of the combined effects of both programs has not been performed so far.…”
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Socio-economic problems of hydrogen energy development by M. A. Pletnev, A. N. Kopysov

“…To solve this problem, the method of analyzing the regulatory framework, monographic, scientific and analytical literature, program documents of various levels, real steps of the authorities in the implementation of the fourth energy transition was used. DISCUSSIONS. The current economic model of energy production and consumption is based on an increase in entropy, which leads to irreversible changes in the global ecosystem. …”
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A Hydrological–Energy Balance Model to Assess Land Surface Temperature at the Urban Scale: The Case Study of Milano, Italy by Sonia Morgese, Wenchuang Zhang, Francesca Casale, Daniele Bocchiola

“…Particularly, we showed that an increase of green share, ΔVF = + 10%, may correspond to a decrease of ΔLST = −0.26°C. …”
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Structural and Spatial-Functional Changes in the Development of Enterprises in Ukraine by Ivan Burtnyak, Oleksandr Kusnir, Roman Kashevskyi

“…The first approach is confirmed by observations of periodic increases in demand, especially for agricultural land. …”
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Economic Analysis of Global CO₂ Emissions and Energy Consumption Based on the World Kaya Identity by Alina Yakymchuk, Simone Maxand, Anna Lewandowska

“…Thus, an unexpected increase in the population likely does not have short-term effects on CO₂ emissions, and the responses to GDPpc and energy intensity both decrease after some periods, while the shock in carbon intensity shows a significant effect even after 10 years. …”
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Stress and influencing factor among children diagnosed with cancer at hospitals in Nepal: a cross-sectional study by Surya Kamal Shahi, Panpan Wang, Jinjin Gu, Rajendra Man Shrestha, Peng Wang

“…The linear regression model showed that stress is associated with socio-demographic variables sex in which female children are more stressed (β = 1.750 (95% CI: 0.46, 3.03) P < 0.05) and clinical features duration of diagnosis as the time increase (12 < Month ≤ 24) level of stress decreased (β =-1.730 (95% CI: -3.20,-0.25) P < 0.05. …”
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Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension by Hannah L. Smith, Bethany L. Goodlett, Gabriella C. Peterson, Emily N. Zamora, Ava R. Gostomski, Brett M. Mitchell

“…SSHTN is defined by an increase in blood pressure (BP) in response to high dietary salt, and is associated with heightened cardiovascular risk, renal damage, and immune system activation. …”
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Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…Whey protein (WP) is a highly nutritious, commercially available alternative food source that is used primarily as a food supplement by athletes and physically active individuals to provide them with essential amino acids and bioactive peptides, and additional benefits have been attributed to WP consumption. In this context, the objective of this review was to explore current evidence regarding the consumption of different WP supplements in sports nutrition to elucidate their efficiency in affecting muscle hypertrophy, physical performance, response to muscle injury, weight loss, and body composition changes. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Investigating the Relationship between Types of Deprivation and Social Tolerance among Citizens of Tehran by Negar Firouzeh, Khadijeh Safiri

“…Specifically, as these forms of deprivation increased (excluding political deprivation), social tolerance tended to decrease. …”
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Cognitive and non-cognitive factors predict pigs’ positions in an aggression social network by Lucy Oldham, Saif Agha, Gareth Arnott, Mark Brims, Irene Camerlink, Agnieszka Futro, Victoria E. Lee, Andrea Doeschl-Wilson, Simon P. Turner

“…Betweenness centrality (a network position linking otherwise unconnected individuals) increased with network size and decreased with body weight. …”
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Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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FINANCIAL SUPPORT FOR FORMATION OF INTELLECTUAL CAPITAL OF ENTERPRISES by V. G. Semenova

“…The formation and active use of intellectual capital of the enterprise becomes a guarantee of increasing its competitiveness and efficiency of activities both in the context of solving current problems and in the strategic perspective. …”
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INTERNATIONAL EXPERIENCE AND TRENDS OF INNOVATIVE DEVELOPMENT OF ARCTIC TERRITORIES by M. Dudin, N. Ivashchenko

“…This approach is fundamentally fl awed and fraught with a number of threats, because other countries do not decrease, but only increase their interest in this issue; Territorial opposition to all those involved in the topic of causing instability in the Arctic region, but does not represent a real threat for the emergence of large-scale conflict. …”
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Beyond the brain: early autonomic dysfunction in Alzheimer’s disease by Carmen Nanclares, Inés Colmena, Alicia Muñoz-Montero, Andrés M. Baraibar, Ricardo de Pascual, Aneta Wojnicz, Ana Ruiz-Nuño, Antonio G. García, Adrián Gironda-Martínez, Luis Gandía

“…Noradrenaline levels increased in both plasma and brain, while dopamine decreased peripherally but paradoxically increased in the prefrontal cortex and hippocampus. …”
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