PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS

“… Myosteatosis, defined as an ectopic fat accumulation within skeletal muscle, has gained increasing clinical relevance as it fits within the context of metabolic disorders and aging. …”
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Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy by Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini

“…The obtained results suggest that other transport proteins participate in Ca2+ homeostasis in FD and their dysfunction may be directly involved in nociception. In this context, plasma-membrane Ca2+ ATPases exhibited reduced activity in FD, leading to an increased resting [Ca2+]i in sensory neurons. …”
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HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS by В. Диннік, О. Диннік, С. Новохатська

“… Stress is currently the most significant factor contributing to reproductive function disorders and has become a major public health problem in the 21st century. …”
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Digital Transformation Strategy of Aerospace Industry by Pu Sun, Weijia Yuan, Fengli Sun, Qian Shi, Shengyou Shi, Guoqing Wang

“…The aerospace industry, as an important representative of high-end manufacturing, plays an irreplaceable role in the development of new-quality productivity. In the context of increasingly complex projects and rapid iteration of new technologies, the development model of the aerospace industry is facing significant challenges and urgently requires digital transformation to promote high-quality development of the industry. …”
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Rubinstein-Taybi syndrome with ganglioneuroblastoma: a case report and literature review by Jiaji Zhou, Tang Dan, Lan Zeng, Fu Xiong, Guanghuan Pi, Ai Chen, Haiting Liu, Shuyao Zhu

“…However, the association between CREBBP variants and an increased risk of tumors remains unknown, despite multiple reports of tumor comorbidities related to RSTS. …”
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Facilitating active participation in anticoagulant decisions in advanced kidney disease: co-production of a question prompt list by Kathrine Parker, Abigail Needham, Jecko Thachil, Sandip Mitra, Penny Lewis

“…Currently, there are no support tools for people with chronic kidney disease regarding anticoagulant therapy decisions. …”
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Matrix Gla Protein – a new marker for colorectal cancer detection? A systematic review by Mirela-Georgiana Perné, Lorena Ciumărnean, Olga-Hilda Orășan, Vasile Negrean, Teodora-Gabriela Alexescu, Mircea Vasile Milaciu, Ioana Roșca, Răzvan Dan Togănel, Gabriel Emil Petre, Lucia Procopcoiuc, Cristina Drugan, Alexandra Crăciun

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ENHANCING ACCOUNTABILITY FOR MAKING CITIES RESILIENT AND ROLE OF SUPREME AUDIT INSTITUTIONS by Arife Coşkun, Latif Gürkan Kaya

“…Currently,more and more people are settling in cities, located in disaster prone areas. …”
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Modeling consequences of spatial closures for offshore energy: Loss of fishing grounds and fishery‐independent data by M. Campbell, J. F. Samhouri, J. W. White

“…Abstract Many jurisdictions are currently pursuing renewable sources of energy from the ocean, including offshore wind farms (OWFs). …”
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Contrasting Effect of Curcumin on Hepatitis B Virus Replication According to the Hepatoma Cell Line by María Mercedes Elizalde, Pedro Fuentes, Diego Chiappetta, Diego Martín Flichman

“…In recent decades, considerable advances have been achieved in the treatment of chronic hepatitis B. However, the currently available drugs have shortcomings. In this context, several natural compounds have been proposed as potential agents to improve either the outcome of antiviral treatment or the progression of chronic infection, with curcumin being one of the most evaluated compounds due to its pleiotropic antiviral activity. …”
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A review of private forest owner typologies with potential to contribute to social milieu research in forest policy by Peter K. Aurenhammer, Max Krott

“…Furthermore, their broader geographical scope can complement the currently German-centric milieu literature.In conclusion, PFO typology research and social milieu research are mutually beneficial. …”
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Assessing crack formation and strain distribution in concrete structures using externally installed fiber optic sensors by Henrik Becks, Matthias Högemann, Josef Hegger, Martin Classen

“…The structural integrity of many European bridges is increasingly compromised by rising traffic loads and gradual deterioration. …”
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Performance Evaluation and Optimization of 3D Gaussian Splatting in Indoor Scene Generation and Rendering by Xinjian Fang, Yingdan Zhang, Hao Tan, Chao Liu, Xu Yang

“…Firstly, utilizing a self-collected dataset, a comprehensive comparison was conducted among COLLI-SION-MAPping (abbreviated as COLMAP (V3.7), an open-source software based on Structure from Motion and Multi-View Stereo (SFM-MVS)), Context Capture (V10.2) (abbreviated as CC, a software utilizing oblique photography algorithms), Neural Radiance Fields (NeRF), and the currently renowned 3DGS algorithm. …”
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Justification on Choosing Screw Pumping Units as Energy Efficient Artificial Lift Technology by D. I. Sidorkin, K. S. Kupavykh

“…It is recognized that the number of publications in the area of energy efficiency is growing steadily. Currently Russian oil and gas industry are facing the task of accelerating reduction of energy consumption while preserving, or even increasing, production rates. …”
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HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data. by Sára Sáray, Christian A Rössert, Shailesh Appukuttan, Rosanna Migliore, Paola Vitale, Carmen A Lupascu, Luca L Bologna, Werner Van Geit, Armando Romani, Andrew P Davison, Eilif Muller, Tamás F Freund, Szabolcs Káli

“…These models were usually built to capture a few important or interesting properties of the given neuron type, and it is often unknown how they would behave outside their original context. In addition, there is currently no simple way of quantitatively comparing different models regarding how closely they match specific experimental observations. …”
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Meta-analysis on the effects of chemical stressors on freshwater ecosystem functions by Alexander Feckler, Ralf Schulz, Ralf B. Schäfer

“…Conclusions Our analyses demonstrate the potential to derive chemical stress–ecosystem function relationships from currently available data, which already reveal adverse effects on specific ecosystem functions. …”
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Immune factors and their role in tumor aggressiveness in glioblastoma: Atypical cadherin FAT1 as a promising target for combating immune evasion by Manvi Arora, Archismita Kundu, Subrata Sinha, Kunzang Chosdol

“…The FAT atypical cadherin 1 (FAT1) has shown context/tissue-dependent effects in cancers of different tissue origins, with either oncogenic or tumor suppressor roles. …”
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Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review by Marc Lecoultre, Valérie Dutoit, Paul R Walker

“…In this context, a clear understanding of the impact of TAM phagocytosis on both innate and adaptive immunity is critical. …”
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Determining the Cost-Effectiveness of Home Care: A Scoping Review by Katerina Gousia, Hansel Teo, Stacey Rand, Florin Vadean

“… Context: The demand for long-term care services provided at home (home care) has increased over time. …”
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Advancements and Challenges in the Management of Prosthetic Valve Endocarditis: A Review by Francesco Nappi

“…It is a significant concern in the field of cardiology, and the epidemiology of PVE has seen notable developments over the last five decades. The disease currently affects an older demographic and is becoming increasingly prevalent in patients with transcatheter-implanted valves. …”
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