Coordinated regulation of timing and strength of synaptic outputs by adrenergic receptors through control of action potentials in Purkinje cells by Kei Furukawa, Kei Furukawa, Shin-ya Kawaguchi

“…We demonstrate that Purkinje cell axons exhibit negative control of action potentials in amplitude and conduction velocity by β-adrenergic receptors in a manner dependent on the axonal length through specific reduction of axonal Na+ currents. On the other hand, β-adrenergic receptors increased presynaptic release probability without changing the amount of readily releasable vesicles in axon terminals of Purkinje cells. …”
Get full text

The evolution and scope of Article 38 of the Convention on the Rights of the Child in a globalizing world by Dawid Stadniczeńko

“…Observational method, document examination method, method of analysis and criticism of literature Results The scope of contemporary research on childhood within the context of international discourse reveals the necessity of revising the approach to children and their issues. …”
Get full text

Climate science for 2050 by Guy Brasseur, Guy Brasseur, Detlef Stammer, Pierre Friedlingstein, Pierre Friedlingstein, Gabriele Hegerl, Tiffany Shaw, Kevin Trenberth, Kevin Trenberth, Jadwiga Richter, Carolina Vera, André Berger, Helen Cleugh, Steve Easterbrook, Paul Edwards, Daniela Jacob, Michael Mann, Valérie Masson-Delmotte, Gavin Schmidt, Mary Scholes, Thomas Stocker, Martin Visbeck, Guoxiong Wu

“…Finally, we speculate about the values and ethics of climate science and the nature of climate research in a world that will be increasingly affected by global warming in a geopolitical context very different from that of recent decades.…”
Get full text

Innovative Thermosensitive Composite Materials: Merging Poloxamer PF‐127 and Polysaccharides for Enhanced Functional Properties by Marcos Blanco‐López, Inmaculada deDios‐Pérez, Álvaro González‐Garcinuño, Antonio Tabernero, Eva Martín del Valle

“…Abstract Currently, new cancer treatment options are being developed following tumor resection surgery, with a focus on minimizing invasiveness and reducing systemic toxicity to lower the risk of recurrence. …”
Get full text

Assessing coupled human-flood interactions using LiDAR geostatistics and neighbourhood analyses by Morgan J. Breen, Abiy S. Kebede, Carola S. König

“…The paper integrates well-established methods from other spheres of flood risk assessment in a novel way to explore the currently poorly understood Safe Development Paradox (SDP) phenomenon in coastal settings. …”
Get full text

A Methodological Proposal for Determining Environmental Risk Within Territorial Transformation Processes by Marco Locurcio, Felicia Di Liddo, Pierluigi Morano, Francesco Tajani, Laura Tatulli

“…The built assets and the real estate sector play a key role in this context; indeed, being among the first ones to be exposed to the effects of climate change, they serve as a crucial tool for the implementation of governance strategies that are more focused on environmental issues. …”
Get full text

Unveiling polyoxometalate redox properties at the nanoscale by Volatron, Florence, Izzet, Guillaume, Vuillaume, Dominique,  Proust, Anna

“…They hold promise as charge storage nodes in multilevel nonvolatile memories and resistive switching devices, areas of interest currently boosted by the development of neuromorphic computing. …”
Get full text

A virus becomes a global concern: research activities on West-Nile virus by Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Friederike Reuss, Ruth Müller, David A. Groneberg, Dörthe Brüggmann

“…Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. …”
Get full text

Family Medicine for internally displaced persons in Mali: A training of trainers approach by Drissa M. Sidibé, Ann Isabelle Grégoire, Véronique Lisée, Pierre Rodrigue Traoré, Inhissa B. Bengaly, Aboubakary Konaté, Ibrahim H. Sidibé, Sabina Abou Malham, David-Martin Milot, Gabriel Blouin-Genest

“…Mali is currently experiencing a polycrisis, characterised by the interplay of growing socio-political insecurity, massive population displacements and recurrent tensions in the functioning of the health system and the provision of care. …”
Get full text

Rhizosphere Microbiome Diversity Potentially Supports Robust Nature of Field Pennycress (Thlaspi arvense L.) in Dryland Cropping Systems of Eastern Washington by Andrew R. Spishakoff, Pubudu Handakumbura, Chaevien Clendinen, Karen A. Sanguinet, Tarah S. Sullivan

“…ABSTRACT Field pennycress (Thlaspi arvense L.) is an annual in the Brassicaceae family and is currently being developed as an oilseed intermediate crop suitable for renewable biodiesel and jet fuel. …”
Get full text

Creatine as a Compound and Supplement Metabolism, Mechanism of Action, Effects, and Adverse Effects - A Review by Szymon Szypulski, Aleksandra Zielińska, Sebastian Iwaniuk, Ignacy Maciejewski, Kinga Tylczyńska, Jakub Skiba, Maria Michalska, Kinga Kowalik, Zuzanna Skiba, Natalia Tylczyńska

“…Over time, attention has also shifted toward exploring creatine’s potential applications in other areas of medicine, as well as its use across various populations and age groups. Currently, the significance and importance of creatine are being highlighted not only in the context of its use across various sports disciplines, but also for its demonstrated beneficial effects in a range of medical conditions. …”
Get full text

Prevalence and associated factors of mammography uptake among the women aged 45 years and above: policy implications from the longitudinal ageing study in India wave I survey by Priyanka Sharma, Dipak Das, Divya Khanna, Atul Budukh, Anita Khokhar, Satyajit Pradhan, Ajay Kumar Khanna, Pankaj Chaturvedi, Rajendra Badwe

“…Among women in 45–59 years age group, secondary or higher education, being currently in union, having diabetes, neurological illness, hearing problems, and reproductive health problems, better cognition level, and self-history of cancer were found to be associated with increased mammography uptake. …”
Get full text

The Impact of brain-gut microbiota composition on depression by Aleksander Ptasiński, Marta Targońska, Oskar Targoński, Adrianna Madej, Adrian Suława, Julia Furgalska, Sebastian Fedorowicz, Aneta Basiak, Rafał Niekurzak, Agnieszka Buczek

“…It is important to note the significant individual variability in the context of changes in the depressive microbiome and the response to various modification methods. …”
Get full text

Analysis of Factors Influencing Millennial Consumers' Decision in Buying Halal Cosmetics by Novalini Jailani, Susminingsih, Hendri Hermawan Adinugraha, Fatimah Kari, Adib Muhammad

“… The market potential of the halal cosmetics is currently very promising and the use of cosmetics among millennials is increasing. …”
Get full text

Replacing penalties by V. Stepashin

“…It is important in the context of the topic and the possibility of a sentence of imprisonment as a substitute punishment in cases where the original purpose of the strict measures excluded. …”
Get full text

PROBLEMS AND PROSPECTS OF THE EUROPEAN REGIONAL ORDER by L. A. Dymova

“…Building a stable architecture of the European security system is one of the essential conditions of the European regional order, however contradicting approaches of the parties acknowledge that political and ideological barriers between the East and the West continue to exist. In the context of increasing security threats transatlantic partnership does not lose the relevance though the tough course of the US and its desire to reinforce its leadership in Europe often meets the extreme disapproval on the part of the Europeans. …”
Get full text

The specificity and flexibility of l1 reverse transcription priming at imperfect T-tracts. by Clément Monot, Monika Kuciak, Sébastien Viollet, Ashfaq Ali Mir, Caroline Gabus, Jean-Luc Darlix, Gaël Cristofari

“…Third, efficient priming in the context of duplex DNA requires a 3' overhang. This suggests the possible existence of additional DNA processing steps, which generate a single-stranded 3' end to allow L1 reverse transcription. …”
Get full text

Semantic approaches for query expansion: taxonomy, challenges, and future research directions by Azzah Allahim, Asma Cherif, Abdessamad Imine

“…Of late, semantic query expansion techniques have attracted increased interest among researchers since these techniques offer more pertinent and practical results to the users. …”
Get full text

<i>Xanthium strumarium</i> L.: chemical components and biological activity (review) by N. S. Popkov, V. D. Zamyslova, M. N. Povydysh

“…The problem of using Common Cocklebur in the context of modern evidence-based medicine is becoming increasingly important.Text. …”
Get full text

Space 4.0 – a common, democratic European space, part 2 by Ryszard S. Romaniuk, Piotr Orleański

“…The transformation is related to the need to maintain the changes in a reasonable legal system so as not to experience the „Wild West” again, this time in space. It is currently difficult to establish strict rules regarding the still distant colonization of Mars, but undoubtedly establishing rules for the use of the LEO area, i.e. the already crowded low Earth orbits, is becoming an increasingly urgent necessity. …”
Get full text