Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen, Wenyi Ye

“…Context Hyperpigmentation, a common skin condition marked by excessive melanin production, currently has limited effective treatment options.Objective This study explores the effects of Tao-Hong-Si-Wu decoction (THSWD) on hyperpigmentation and to elucidate the underlying mechanisms.Materials and methods We employed network pharmacology, Mendelian randomization, and molecular docking to identify THSWD’s hub targets and mechanisms against hyperpigmentation. …”
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Serum markers of bone fragility in type-2 diabetes mellitus by Rucsandra Dănciulescu Miulescu, Loreta Guja, Lavinia Claudia Ochiana, Anca Ungurianu, Oana Cristina Șeremet, Emil Ștefănescu

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HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS by В. Диннік, О. Диннік, С. Новохатська

“…At OM onset, nearly 20% of participants exhibited low E2 levels. With increased disease duration (years 2–3), the proportion of adolescents with low E2 decreased while those with elevated E2 increased. …”
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A guide to evade hallucinations and maintain reliability when using large language models for medical research: a narrative review by Sangzin Ahn

“…Large language models (LLMs) are increasingly prevalent in medical research; however, fundamental limitations in their architecture create inherent reliability challenges, particularly in specialized medical contexts. …”
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Key Barriers to Personalized Learning in Times of Artificial Intelligence: A Literature Review by Gina Paola Barrera Castro, Andrés Chiappe, María Soledad Ramírez-Montoya, Carolina Alcántar Nieblas

“…Personalized learning (PL) has emerged as a promising approach to address diverse educational needs, with artificial intelligence (AI) playing an increasingly pivotal role in its implementation. This systematic literature review examines the landscape of PL across various educational contexts, focusing on the use of AI and associated challenges. …”
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Being there but where? Sense of presence theory for virtual reality applications by Stefano Triberti, Caterina Sapone, Giuseppe Riva

“…As immersive technologies become increasingly prevalent in shared environments and sensitive contexts such as education and healthcare, this more sophisticated understanding of presence becomes crucial for designing effective virtual experiences. …”
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Patient partner engagement in the publication process: challenges and possible solutions by Krista E. Cooksey, Mark Neuman, Mara Bollini, Bethany Pennington, Hugo de O. Campos, Kathleen Oberst, Melissa Wurst, Mary C. Politi

“…When patients contribute to publications, they can bring unique perspectives that may enhance the impact, reach, and utility of the research in real-world contexts. Currently, there is limited systematic guidance to support patient partners as they navigate this complex publication process. …”
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A Systematic Review of EEG Studies on the Neural Effects of Quran Listening by Hamid Majidi, Alireza Rajabi-Tavakkol

“…Findings indicate that listening to Quranic verses is associated with increased alpha and theta power, which correlates with relaxation and improved emotional states in participants, including non-Muslims. …”
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Experiential Graphic Design: Informing, Inspiring, and Integrating People in Physical Spaces—A Review by Gorana Petković, Suzana Pasanec Preprotić, Anamarija Kozjan Cindrić

“…Experiential graphic design (XGD) has increased in importance over the past decade, with technological advances and a focus on user engagement. …”
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‘Nous fêterons’ or ‘On va fêter’? by Valerie Hekkel, Friederike Schulz, Marta Lupica Spagnolo

“…While expert-knowledge injection significantly increased the usage of formal variants, there was no systematic influence of age, birth year, or interview year on variant selection. …”
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CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers by Jiasen Sun, Hui Ren, Jiawen Wang, Xiang Xiao, Lin Zhu, Yanyan Wang, Lili Yang

“…CHAC1, an essential regulator of oxidative stress and ferroptosis, is increasingly recognized for its significant roles in these cellular processes and its impact on various human diseases and cancers. …”
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Lifelong Learning and Employability in the Danube Region Countries: Influences and Correlations by Constanţa-Nicoleta Bodea, Maria-Iuliana Dascălu, Gordana Velikic, Stelian Stancu

“…The conclusions of the current study are particularly important in the Romanian context, as the employment rate of recent graduates is in a decreasing trend, but also for all the Danube Region ex-communist countries, which have to boost their employment rates as well, to assure their economical growth. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Telehealth Interventions in Pharmacy Practice: Systematic Review of Reviews and Recommendations by Rachel Lai Kay Chong, Andrew Siang Ee Chan, Crystal Min Siu Chua, Yi Feng Lai

“…Our results show a strong push to integrate telehealth into future pharmacy practice, with the United States leading the way in adoption, demonstrating increased care access, quality, and patient safety. …”
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Progress in visible-light-activated photocatalytic coatings to combat implant-related infections: From mechanistic to translational roadmap by Bruna E. Nagay, Samuel S. Malheiros, Maria H.R. Borges, Conrado Aparicio, Jeroen J.J.P. van den Beucken, Valentim A.R. Barão

“…Biomedical and dental implants have enhanced healthcare but concurrently increased the risk of infections. Innovations in smart biomaterials, especially those responding to light stimuli through photocatalytic mechanisms, are emerging as promising solutions for activating targeted antimicrobial responses. …”
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Federated Deep Learning for Scalable and Privacy-Preserving Distributed Denial-of-Service Attack Detection in Internet of Things Networks by Abdulrahman A. Alshdadi, Abdulwahab Ali Almazroi, Nasir Ayub, Miltiadis D. Lytras, Eesa Alsolami, Faisal S. Alsubaei, Riad Alharbey

“…Industry-wide IoT networks have altered operations and increased vulnerabilities, notably DDoS attacks. IoT systems are decentralised. …”
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Effectiveness of laughter therapy with healthcare clowns on the mood of hospitalised adults by Yelsyn Mauricio Porras-Jiménez, Carmen Álvarez-Nieto, Karen Lizeth Romero-Granados, César Augusto Pinzón-Ordoñez, Isabel María López-Medina

“…Discussion: Current evidence supports laughter therapy with healthcare clowns as a tool to foster positive emotions, reduce negative psychological symptoms, and improve emotional well-being in various contexts, highlighting the importance of collaborative implementation with medical staff to strengthen well-being in healthcare settings. …”
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Academic Motivation in English Online Classes: A Comparative Study of Universities in Malaysia and Indonesia by Suhaida Omar, Wan Yusoff Wan Shaharuddin, Nik Ahmad Farhan Azim @ Nik Azim, Noor Syamimie Mohd Nawi, Noraini Zaini, Wandi Syahfutra

“…This uniformity also implied that although English is a second language in Malaysia, and a foreign language in Indonesia, the undergraduates were not affected by their linguistics, and institutional contexts. This study has contributed towards the extension of the current knowledge involving undergraduates’ academic motivation towards learning English online and suggested that teachers could help to strategise students’ SRL and self-efficacy to increase their English language performances, particularly in the pandemic era. …”
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The Understanding of Willingness to Pay for Clean Drinking Water Through Extended Version of The Theory of Planned Behaviour by Zohaib Ali, Atta Ur Rehman, Muhammad Rafiq

“…It gives stakeholders a chance to observe how extended version of TPB and WTP interact with one another. To increase WTP for getting access to clean drinking water, raise awareness about environmental risks. …”
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Health insurance purchase intentions in the past decade: a systematic review and future research directions by Zhangwei Zheng, Hafizuddin-Syah B.A.M, Hafizah Omar Zaki, Qin Lingda Tan

“…Methods A systematic review was conducted using the TCM (theory-context-methodology) and ADO (antecedent-decision-outcome) frameworks. …”
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