Mind the Gap: Reconciling Formalism and Intuitionism in Computational Design Research by Zeynep Mennan

“…The paper discusses the epistemological and methodological implications of an increasing process of formalisation and naturalisation of knowledge within the context of the complexity paradigm. …”
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Administration of aspirin and risk of pancreatic ductal adenocarcinoma by Arooba Noor Abbasi, Fatimah Bismah Athar, Arooba Lakho

“…While Aspirin shows major benefits in other contexts, its role in PDAC risk reduction appears limited. …”
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Prospects for distributed self-consumption generation in urban circuits with the use of photovoltaic systems by Diego Cordova, Secundino Marrero, Carlos Quinatoa, Manuel Leon

“…Electric distribution systems currently present a marked interest in solving problems related to technical losses, overloading of lines and being able to assimilate the increase in energy demand. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Investigating How Policies and Other Conditions Contribute to Influencing Agricultural GHG Emissions in the EU by Francesco Galioto, Irene Criscuoli, Andrea Martelli, Maria Valentina Lasorella, Ilaria Falconi, Danilo Marandola, Giovanni Dara Guccione, Francesca Varia

“…Based on these facts, we introduce the context of implementation of the 2014–2022 Common Agricultural Policy (CAP), within which many interventions were designed to improve sustainability and increase competitiveness, and we formulate hypotheses on how CAP instruments can contribute differently to influencing GHG emissions from agriculture. …”
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Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

“…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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Assessment of the effect of the COVID-19 pandemic on levels of satisfaction in marital relationships during and post-lockdown by Rasha Aziz Attia Salama, Rabab Gad Abd El-Kader, Talaat Matter Tadross, Shaimaa Hashem Elsalous

“…The current study aimed to assess marital satisfaction during and post the lockdown of the COVID-19 pandemic and explore the factors influencing marital satisfaction among the public. …”
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Expert Consensus on Clinical Application of Lower Limb Rehabilitation Robots by ZHANG Lixin, BAI Dingqun, BAI Yulong, CHEN Wenhua, CHEN Yan, DU Qing, FAN Maohua, HE Hongchen, HUANG Liping, JIA Jie, LI Jianhua, LI Lei, PAN Yu, SU Min, WANG Hongtu, YIN Yong, ZHANG Bi

“…In addition, referencing the latest research, this consensus elaborates on the working principles, classification, clinical application (indications and contraindications, working parameters and operating procedures, safety), and recommendations on clinical application (hemiplegia, paraplegia, musculoskeletal diseases, childhood diseases and other systemic diseases) when using lower limb rehabilitation robots in the current context. Lower limb rehabilitation robots are well-suitable for patients with walking difficulties and long-term bedridden condition. …”
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Taxpayer protection standard in international tax disputes by M. D. Polenchuk

“…This is especially important for those states that do not use arbitration, such as Russia.The main conclusion is that the application of the standard of protection of human right to a fair trial in relation to the taxpayers in the tax treaty disputes resolution procedures is an efficient way to develop the current mutual agreement procedure and arbitration and to increase the confidence of taxpayers in these mechanisms.…”
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Nursing Students’ Computer Self-Efficacy and Attitudes toward Its Use in The Health Care Setting: A Comparative Study by Farida M. Hassona, Aziza Z. F. Ali, Shaimaa M. Nageeb

“… Context: The use of technology and computers in health care has been reported to improve nurses' decision-making and competencies, which in turn increase the quality of health-care practice. …”
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Addressing the Socioemotional Dimension of Medical Education: Protocol for a Scoping Review of Student-Driven Development Strategies by Cintia Canato Martins, Marco Antônio Ribeiro Filho, Christian Guilherme Capobianco dos Santos, Luana Ribeiro Altrão lorino, João Daniel de Souza Menezes, Matheus Querino da Silva, Loiane Letícia dos Santos, Emerson Roberto dos Santos, Natalia Almeida de Arnaldo Silva Rodriguez Castro, Helena Landin Gonçalves Cristóvão, Randolfo dos Santos Júnior, Gerardo Maria de Araújo Filho, Patrícia da Silva Fucuta, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Denise Cristina Móz Vaz Oliani, Neide Aparecida Micelli Domingos, Maria Cristina de Oliveira Santos Miyazaki, Júlio César André

“… BackgroundThe current international context, marked by complex global challenges, necessitates the rapid intervention of higher education institutions to contribute to social transformation. …”
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Exploring the feasibility of establishing a core set of sexual, reproductive, maternal, newborn, child and adolescent health indicators in humanitarian settings: a multimethods, mu... by Angel Foster, Allisyn C Moran, Loulou Hassan Kobeissi, Lale Say, Manizha Ashna, Kassandre Messier, Kathleen Louise Strong

“…With the collapse of health systems, reduced resources and increased vulnerabilities from displacement, there is a need to strengthen current practices and ensure the delivery of comprehensive sexual, reproductive, maternal, newborn, child and adolescent health (SRMNCAH) services. …”
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Global road extraction using a pseudo-label guided framework: from benchmark dataset to cross-region semi-supervised learning by Xiaoyan Lu, Yanfei Zhong, Zhuo Zheng, JunJue Wang, Dingyuan Chen, Yu Su

“…Recent advancements in satellite remote sensing technology and computer vision have enabled rapid extraction of road networks from massive, Very High-Resolution (VHR) satellite imagery. However, current road extraction methods face the following limitations: 1) Insufficient availability of accurate and diverse training datasets for global-scale road extraction; 2) Costly and time-consuming manual labeling of millions of road samples; and 3) Limited generalization ability of deep learning models across diverse global contexts, resulting in better performance for regions well-represented in the training dataset, but worse performance when faced with domain gaps. …”
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Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms o... by Razi Khalaila, Karl Skorecki

“…In the absence of a consistent mechanistic explanation for differential kidney injury, we propose pursuing three interrelated avenues of investigation informed by prior epidemiological and mechanistic evidence linking them to APOL1’s cytotoxicity: (1) Molecular evolution of APOL1 haplotypes in human populations, (2) APOL1 splicing and consequent splice isoforms, (3) Interaction of APOL1 with other APOL gene family members, prioritizing APOL3. In the current study, we use reanalysis of population genetics datasets to resolve the haplotype contexts of all protein-altering APOL1 variants, uncovering previously unrecognized variant–haplotype couplings. …”
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When IEEE 802.11 and 5G Meet Time-Sensitive Networking by Mahin K. Atiq, Raheeb Muzaffar, Oscar Seijo, INaki Val, Hans-Peter Bernhard

“…Time-sensitive networking (TSN) standards aim at providing vendor agnostic, reliable, and deterministic communications over the Ethernet, but lack in flexibility and modularity provisions. In this context wireless communication systems are preferred given the obvious benefits in terms of increased flexibility, reduced deployment & maintenance costs, and inherent mobility support. …”
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Incidental findings related to genes associated to HAE-nC1INH: how to proceed? by Anastasios E. Germenis, Despina Sanoudou

“…The mainstreaming of genomic technology and the increasing use of next generation sequencing have increased the possibility of an unintentional detection of HAE-nC1INH pathogenic variants and allowed the incidental finding of variants of uncertain significance (VUS) in the relevant genes. …”
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Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank by Muhammad Ammar Zahid, Shahenda Salah Abdelsalam, Hicham Raïq, Hanan H. Abunada, Aijaz Parray, Abdelali Agouni

“…Conversely, in the diabetic cohort, higher Sestrin2 levels were paradoxically linked to increased triglycerides (OR: 1.57), the product of triglyceride glucose and waist circumference (OR: 1.8), body fat (OR: 1.72), waist circumference (OR: 1.82), waist-to-hip ratio (OR: 1.96) and metabolic syndrome (OR: 1.48).ConclusionsThese findings suggest that Sestrin2 may play a complex and context-dependent role in metabolic regulation, potentially serving as a protective factor in healthy individuals but contributing to metabolic dysfunction in the context of established diabetes. …”
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Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapy by Ronald Mulebeke, Adoke Yeka, Jean-Pierre van Geertruyden

“…Thus, tailoring strategies to the specific local context and transmission dynamics is essential for maximizing impact. …”
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Computer literacy as a condition for the formation of future specialists in education by Larisa Gennadievna Zvereva, Irina Alexeevna Pogodina

“…Due to the rapid society informatization and learning conditions during a pandemic, there is an increasing need to improve the computer literacy of current and future teachers, as a computer is the main device in the work of a teacher and in teaching a student in the modern world. …”
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New forms of production organization: pearl companies by L. V. Kuropatkina

“…In this context, G. B. Kleiner proposed the concept of pearl enterprises as organizations that ensure the long-term effectiveness of the activities of each employee, a team of departments and the company as a whole by expanding the range and increasing the flexibility of formal and informal, hierarchical and non-hierarchical management models used in its various segments. …”
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