In Silico Evaluation of Novel 2-Pyrazoline Carboxamide Derivatives as Potential Protease Inhibitors Against <i>Plasmodium</i> Parasites by Yusuf Jimoh, Idris Yunusa Abdullah, Asmau Nasir Hamza, Maryam Abdullahi, Jibril Ahmadu, Lukman Ali Hassan, Muhammad Shamsudeen Yakubu, Zukhruf Salami

“…The biological implications of these findings are significant, as they suggest that these novel ligands could be effective against <i>Plasmodium</i> parasites, particularly in the context of increasing resistance to current antimalarial drugs. …”
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The interplay between pulse width and activation depth in TENS: a computational study by Alexander Guillen, Dennis Q. Truong, Yusuf O. Cakmak, Sheng Li, Abhishek Datta, Abhishek Datta

“…In fact, longer pulse width has been empirically shown to deliver current into deeper tissues, but in context of other electrical stimulation modalities. …”
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Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions by Nurlan Zhangabay, Aizhan Zhangabay, Kenzhebek Akmalaiuly, Akmaral Utelbayeva, Bolat Duissenbekov

“…This area is becoming particularly relevant in the context of global challenges related to climate change, rising energy costs and increased environmental requirements. …”
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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation by Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper

“…Background Immunosuppressive therapy or T-cell depletion in transplant patients can cause uncontrolled growth of Epstein-Barr virus (EBV)-infected B cells resulting in post-transplant lymphoproliferative disease (PTLD). Current treatment options do not distinguish between healthy and malignant B cells and are thereby often limited by severe side effects in the already immunocompromised patients. …”
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Arthroscopic-Assisted vs. Fluoroscopic-Only ORIF of Distal Radius Fractures: Clinical and Economic Perspectives by Wolfram Demmer, Antonina Jakob, Fabian Gilbert, Benedikt Fuchs, Sinan Mert, Nikolaus Wachtel, Riccardo Giunta, Verena Alt

“…Our findings demonstrate that DRF treatment, regardless of the method used, is either not or only marginally cost-covering under the current German reimbursement structure. In the context of the ongoing shift towards outpatient hand surgery, including the management of DRF, adequate reimbursement rates are necessary to ensure the economic viability of DRF management, particularly for complex intra-articular fractures requiring arthroscopic assistance.…”
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Pesticide Residues in Fruits and Vegetables from Cape Verde: A Multi-Year Monitoring and Dietary Risk Assessment Study by Andrea Acosta-Dacal, Ricardo Díaz-Díaz, Pablo Alonso-González, María del Mar Bernal-Suárez, Eva Parga-Dans, Lluis Serra-Majem, Adriana Ortiz-Andrellucchi, Manuel Zumbado, Edson Santos, Verena Furtado, Miriam Livramento, Dalila Silva, Octavio P. Luzardo

“…Food safety concerns related to pesticide residues in fruits and vegetables have increased globally, particularly in regions where monitoring programs are scarce or inconsistent. …”
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Mast cell activation syndrome: The overdiagnosis problems by N. V. Mikryukova, N. M. Kalinina

“…The incidence of mast cell activation syndrome (MCAS) has increased since first definition as a mastocytosis-like phenotype. …”
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Tissue Specific Effects of Chronic Sustained Hypoxia on Oxidative Stress: Role of Cilnidipine, a Dual L/N Type Calcium Channel Blocker by Shrilaxmi Bagali, Akram Naikwadi, Kusal K. Das

“…Background: Blood flow, metabolic rate and oxygen requirements of an organ guide the extent of oxidative stress experienced by any tissue in response to chronic hypoxia. Currently cilnidipine is used in the management of hypertension and its antioxidant actions are gaining wide interest. …”
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Professional pharmacy Services' outcomes performance measurement: A narrative review by Lígia Reis, João Gregório

“…To do so is important to understand which outcome performance indicators are currently being used and how added value is proven. …”
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Counting animals in orthomosaics from aerial imagery: Challenges and future directions by Ismael V. Brack, Camila Ferrara, German Forero‐Medina, Enrique Domic‐Rivadeneira, Omar Torrico, Kevin Thomas Wanovich, Benjamin Wilkinson, Denis Valle

“…Abstract The use of drones to survey and monitor wildlife populations has increased exponentially. A common protocol used for data collection is planning flights with substantial overlap between successive photographs and lateral lines and then creating orthomosaics by merging the collected images. …”
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Rhizosphere Microbiome Diversity Potentially Supports Robust Nature of Field Pennycress (Thlaspi arvense L.) in Dryland Cropping Systems of Eastern Washington by Andrew R. Spishakoff, Pubudu Handakumbura, Chaevien Clendinen, Karen A. Sanguinet, Tarah S. Sullivan

“…ABSTRACT Field pennycress (Thlaspi arvense L.) is an annual in the Brassicaceae family and is currently being developed as an oilseed intermediate crop suitable for renewable biodiesel and jet fuel. …”
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Efficient Edge AI for Next Generation Smart Mirror Applications by Nils Kucza, Florian Porrmann, Christian Stollenwerk, Jens Hagemeyer

“…Optimizations using pruning are evaluated and show improvements in energy per processed frame, required calculations per frame (50% reduction), and accuracy (increased for some classes by 15%). Currently the best solution regarding efficiency and optimized DNN models achieves 30FPS for object, gesture, and face detection models simultaneously while consuming around 38Watts, resulting in 1.3mJ per frame.…”
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Effect of Self-Care Strategies on Health Outcomes of Patients with Hepatocellular Carcinoma by Hala Sheta, Nehal Abo El-Fadl

“… Context: Hepatocellular carcinoma is the prevailing form of primary liver cancer among adults and currently ranks as the primary cause of mortality in cirrhosis individuals. …”
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Adolescent and parental proxy online record access: analysis of the empirical evidence based on four bioethical principles by Josefin Hagström, Maria Hägglund, Charlotte Blease

“…Methods In this paper, we apply biomedical ethical principles to explore key questions about adolescents’ and parents’ access to adolescents’ EHRs, with the aim of informing future discussions about the development of ethical and policy practice guidelines. Results Drawing on current empirical research, we find preliminary evidence that in some contexts, patient online record access (ORA) could help to facilitate autonomy for adolescents and parents as well as offering support in managing appointments and medications. …”
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Modelling the efficiency of technological management of agricultural enterprises in economic security by Mykola Vovk, Tetyana Zubro, Elvin Omarov, Bohdan Kolomiiets, Volodymyr Hnydiuk

“…The purpose of this study is to develop a model for assessing the efficiency of technological management of agricultural enterprises in the context of ensuring economic security. The study also focuses on the analysis of key factors affecting the efficiency of technological processes, and on the development of tools for improving management technologies in the context of modern economic challenges and risks. …”
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Advances in synthetic microbial ecosystems approach for studying ecological interactions and their influencing factors by Wei Jiang, Sumeng Wang, Fei Gu, Xiaoya Yang, Qingsheng Qi, Quanfeng Liang

“…This review consolidates current knowledge of synthetic microbial ecosystems and factors influencing their ecological dynamics. …”
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Financial security of Ukraine in debt burden: Assessment and forecasting by Fedir Zhuravka, Yuriy Petrushenko, Svitlana Chorna, Bohdana Huriy, Inessa Yarova, Olga Pankiv, Wojciech Duranowski

“…Regression modeling demonstrated a clear negative correlation between the amount of external debt and the level of financial security, with each increase in the debt burden being accompanied by a decrease in the integral index. …”
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Recent insights in soil nutrient cycling: perspectives from Pinus and Eucalyptus forest studies around the world by Castilho Balbinot L, Marques R, Tonello KC, Pasquetti Berguetti L, Larsen JG

“…This review synthesizes studies focusing on nutrient dynamics in forests of Pinus and Eucalyptus species, highlighting the sensitivity of these systems to current climatic extremes. We emphasize that most research has been conducted predominantly in natural forests and plantations of Pinus (77%), with an increasing trend of studies on Pinus in natural environments and Eucalyptus in planted forests. …”
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Hedgehog Signaling Pathway in Fibrosis and Targeted Therapies by Yuchen Hu, Linrui Peng, Xinyu Zhuo, Chan Yang, Yuwei Zhang

“…We thus highlight the context dependence of Hh signaling, as well as discuss the current status and the challenges of Hh-targeted therapies for fibrosis.…”
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Péri-urbanisation et risques naturels by Laurent Astrade, Céline Lutoff, Rachid Nedjai, Céline Philippe, Delphine Loison, Sandrine Bottollier-Depois

“…A diachronic study of changes in land use between 1956 and 2001 shows how valley infrastructures at the bottom of mountainsides have become increasingly dense. In this context, a survey was carried out among a number of residents in the Lavanchon basin in an attempt to evaluate the degree of awareness that the population has of the natural hazards to which it is exposed. …”
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