Climate Change and Its Impact on Romanian Rural Tourism—A Review of Actionable Knowledge by Liliana Velea, Anisoara Irimescu, Roxana Bojariu, Zenaida Chitu

“…This makes tourism vulnerable to climate change through the direct effect of changes in the attractivity of climate conditions, in addition to the indirect effects due to the expected impacts on other associated socio-economic sectors. In this context, increasing rural tourism resilience to climate change is a complex issue which needs to consider adaptation measures focusing on tourism specifics in synergy with adaptation measures in related sectors (e.g., energy, land and water management, urbanization aspects). …”
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Research on Vehicle Route Optimization for Half-Open Multi-Energy Urban Distribution Considering Order Priority by Mingxuan Zhang

“…Aiming at the current problems of increasingly serious tailpipe pollution of urban distribution vehicles and irrational distribution route planning, we construct a fuel-electric hybrid multi-trip multi-center half-open joint distribution vehicle routing optimization model (F-EHOMTMDVRPOPTW) considering order priority and fuzzy time window, and introduce Tent chaotic mapping combined with an improved discrete sparrow search algorithm (DSSA) with stochastic key encoding strategy for solving. …”
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PUMPING PRESSURE AND FLOW RATE RELATIONSHIP TO REDUCE ENERGY CONSUMPTION IN IRRIGATION SYSTEMS by Esmeralda CHIORESCU

“…In the context of the current energy crisis, electricity consumption, especially by large consumers, must be reduced, rationally, without affecting the quality of services provided. …”
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Why do we need quality measures in emergency medicine? by Shamie Das, Gregg Miller, Christopher Libby, Cameron J. Gettel, Elaine Rabin, Michelle Lin

“…Abstract Quality measures increasingly influence the delivery and reimbursement of care provided in emergency departments. …”
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Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…Following treatment, the proliferation of leukemic cells was significantly decreased and the apoptosis rate was significantly increased, which was more remarkable for venetoclax. …”
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Emotional processing as mechanism of change in brief good psychiatric management for borderline personality disorder: results of a randomized controlled trial by Ueli Kramer, Loris Grandjean, José Blanco Machinea, Hélène Beuchat, Setareh Ranjbar, Yves de Roten, Jean-Nicolas Despland, Philippe Conus, Stéphane Kolly

“…The assessment of mechanisms of change contributes to focus the treatment on the essential ingredients of change. The current study aims to demonstrate the emotional processing as a mechanism of change, assessed in an ecologically valid experimental context, of brief GPM. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

“…Zoledronate ranked first for increasing the BMD in LS, and teriparatide (20mg) was ranked first for decreasing the fracture rate.…”
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miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Conversely, inhibiting miR-34a-5p resulted in an increase in cell growth and a decrease in programmed cell death. …”
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Challenges Caused by Using New Technologies in Holding Public Hearings of Iranian Criminal Courts by Mozhgan Nemati, Nasrin Mehra, Morteza Rasteh

“…Conclusions and Future Research By increasing progress of technology and the need to adapt judicial systems to the requirements of human life and even to respond to crises such as the corona virus epidemic, the criminal proceedings as a collective ritual which have long been based on the face-to-face interaction of activists in the place of hearing, now must be realized in the context of new technologies and with the virtual communication of activists with each other. …”

Non-Thermal Plasma Applications in Maize Seed Remediation, Disinfection, and Improvement for Growth: A Review by Diana Guadalupe Gutierrez-Leon, Jorge Jurado-Paramo, Benjamin Gonzalo Rodriguez-Mendez, Diego Medina-Castro, Regulo Lopez-Callejas

“…However, its production is increasingly threatened by contamination—both chemical and microbiological—as well as climate change, which negatively impacts supply. …”
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Earthquake resilience of densely populated settlements: A strategic approach to mitigate Istanbul’s earthquake risk by Gülru Koca

“…The planning of infrastructure that will serve the increasing population is even more important, especially in cities that have historical importance and have evolved into large metropolises in a short time. …”
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Anti-amyloid Monoclonal Antibodies for Alzheimer’s Disease: A New Hope? (Review) by I. A. Mazerkina

“…This review aimed to examine the prospects and limitations of anti-amyloid DMTs for AD in the context of the current understanding of AD pathogenesis mechanisms.DISCUSSION. …”
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Multi-Temporal Analysis and Techno-Economic Evaluation of Offshore Wind Energy Integration to the Western Interconnection by Li He, Shahnawaz Siddiqui, Sameer Nekkalapu, Sohom Datta, Travis Douville, Konstantinos Oikonomou, Manisha Maharjan

“…To address these challenges, it becomes increasingly crucial to incorporate geographic and technological diversity into the energy mix. …”
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Death and dying in prehospital care: what are the experiences and issues for prehospital practitioners, families and bystanders? A scoping review by Alison Richardson, Michelle Myall, Helen Pocock, Robert Crouch, Charles Deakin, Susi Lund, Alison Rowsell, Mick Arber, Joanne Turnbull

“…Objective To identify the factors that shape and characterise experiences of prehospital practitioners (PHPs), families and bystanders in the context of death and dying outside of the hospital environment where PHPs respond.Design A scoping review using Arksey and O’Malley’s five-stage framework. …”
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Simulation and MCDA-based framework for border crossing process design with static and dynamic control of passenger flow by Piotr Sawicki, Hanna Sawicka

“…The proposed methodology has been applied to redesign the border control process at an airport terminal in the context of new border control procedures. Assuming that 39% of passengers require 10–120% more processing time due to new procedures, the recommended process includes new equipment configuration, increasing the total number of units by two. …”
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Opportunities for a national genomic data governance framework in Australia: a systematic review by Fabian Cannizzo, Miranda E. Vidgen, Rebekah McWhirter, Alan Petersen, Margaret Otlowski, Marco Rizzi, Jasmine Hensley, Ainsley J. Newson

“…Conclusions Our synthesis of the current literature on genomic data governance suggests that the current focus on individual consent as the primary mechanism for protecting data subjects and different priorities in clinical and research governance need to be addressed. …”
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Low dose exposure to dioxins alters hepatic energy metabolism and steatotic liver disease development in a sex-specific manner by Oluwanifemi E. Bolatimi, Yuan Hua, Frederick A. Ekuban, Tyler C. Gripshover, Abigail Ekuban, Bana Luulay, Walter H. Watson, Josiah E. Hardesty, Banrida Wahlang

“…“Dioxins” are persistent organic pollutants (POPs) that are continuously present in the environment at appreciable levels and have been associated with increased risk of steatotic liver disease (SLD). However, current understanding of the role of sex and effects of mixtures of dioxins in SLD development is limited. …”
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Innovating through tradition: kava-talanoa as a culturally aligned medico-behavioral therapeutic approach to amelioration of PTSD symptoms by S. Apo Aporosa, Dennis Itoga, Julia Ioane, Jan Prosser, Sione Vaka, Emily Grout, Martin J. Atkins, Mitchell A. Head, Jonathan D. Baker, Tanecia Blue, David H. Sanday, Mahonri W. Owen, Chris Murray, Karthik Sivanathan, Tua’ipulotu W. Cuthers, Anau Mesui-Henry, Mary-Jane McCarthy, James Bunn, Ifereimi Waqainabete, Helen Turner, Helen Turner, Helen Turner

“…In the broader population, a PTS global epidemic is attending trauma associated with the threatscape of the Anthropocene (increased extreme weather events, natural disasters, conflict, rising poverty, emerging infectious disease) as well as the legacy of the COVID-19 pandemic. …”
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The Circular Kitchen by Bas Jansen

“…While start-ups favor radical innovation, established manufacturers, like the CIK’s producer, opt for incremental improvements (outside of a research context). This suggests that when aiming for large-scale implementation that can only be reached with large-scale production, the feasibility of the design should be prioritized, while still improving environmental performance compared to current, non-circular kitchens. …”
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