Unravelling the myriad physiologic roles of transthyretin: critical considerations for treating transthyretin amyloidosis by Morie A. Gertz, Mandar A. Aras, Nicole Bart, Thomas H. Brannagan, Jan M. Griffin, Amy R. Kontorovich, Andrew M. Rosen

“…While a link between low TTR and severe disease and mortality is well established, it remains unclear whether long-term TTR suppression via ATTR therapies increases risk of disease. Clinical decisions in ATTR, however, should reflect the current understanding of the roles of TTR and the patient’s clinical history.Conclusion TTR serves vital physiologic roles across organ systems. …”
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Smart Campus Tools by Bart Valks

“…The main research question is: How can smart campus tools optimally contribute to the match between demand for and supply of space, both on the current campus and on the future campus? To answer the research question, this PhD dissertation explores the use of Smart campus tools in Dutch and international contexts, at universities and other organisations. …”
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Antifungal and anti-biofilm effects of hydrazone derivatives on Candida spp by Pierre Popczyk, Alina Ghinet, Clovis Bortolus, Laure Kamus, Marc F. Lensink, Jérôme de Ruyck, Boualem Sendid, Faustine Dubar

“…Worldwide, invasive candidiasis are a burden for the health system due to difficulties to manage patients, to the increasing of the resistance of the current therapeutics and the emergence of naturally resistant species of Candida. …”
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Protocol for implementation of intraoperative adverse event recording during WHO checklist sign-out by Guy Haller, Lauren Clack, Christian Schindler, Luzius A Steiner, Salome Dell-Kuster, Dieter Hahnloser, Jörn-Markus Gass, Christoph S Burkhart, Andreas P Vogt, Katrin Burri-Winkler, Anne C Auderset, Valentin Neuhaus, Giorgio Prouse, Judith Winkens, Amanda Van Vegten, Zuzanna Kita, Monika Finsterwald, Nico Streit, Lisa M Willms

“…Introduction & aim Intraoperative adverse events (iAEs) increase postoperative complications, which are devastating to patients and costly to healthcare systems. …”
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Role of Interleukins in Type 1 and Type 2 Diabetes by Roha Asif, Ammara Khalid, Tolga Mercantepe, Aleksandra Klisic, Sana Rafaqat, Saira Rafaqat, Filiz Mercantepe

“…While their diagnostic and therapeutic potential is increasingly recognized, future research must address current limitations through isoform-specific targeting, context-aware interventions, and validation in large-scale, human cohorts. …”
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Oligomerization of the Clostridioides difficile transferase B component proceeds through a stepwise mechanism. by Robin M Mullard, Michael J Sheedlo

“…While Toxin A and Toxin B are thought to drive the pathology associated with the disease, strains that produce CDT have been linked to increased disease severity, higher rates of infection recurrence, and increased incidence of mortality. …”
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Multiple citizenship: international experience and implementation in Ukraine (economic, political and security aspects) by S. Denysiuk, V. Kononenko, N. Rezenkina

“… The article is dedicated to the study of issues related to multiple citizenship in the context of international law and security. In the current conditions of increasing globalization, the regulation of multiple citizenship is becoming ever more relevant, particularly in terms of national security and state sovereignty. …”
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Assessing Farmers’ Prefrences in using Water Resources in Varamin Plain, Iran A Discrete Choice Experiment Technique by Hojatolah Shayeganfard, Mohsen Mehrara

“…In addition to that, in the context of providing policy recommendations, it is suggested to pay serious attention to the issue of agricultural water in the Varamin Plain. …”
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Pharmacological and pupillary evidence for the noradrenergic contribution to reinforcement learning in Parkinson’s disease by Claire O’Callaghan, Frank H. Hezemans, Naresh Subramaniam, Rong Ye, Kamen A. Tsvetanov, Alexander G. Murley, Negin Holland, Isabella F. Orlando, Ralf Regenthal, Roger A. Barker, Caroline H. Williams-Gray, Luca Passamonti, Trevor W. Robbins, James B. Rowe

“…Testing the noradrenergic framework of learning in the context of human diseases offers a test bed for current normative neuroscience theories and may also indicate therapeutic potential. …”
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The impact of non-ionizing electromagnetic radiation emitting devices on the male reproductive system by Michał Sienkiewicz, Bartosz Pawłowski, Magdalena Kłusek, Dorota Zatłoka-Mazur, Filip Klimas, Kacper Rusiński, Bartłomiej Sienkiewicz

“…However, studies conducted in this context often provide inconsistent results, hence the exact effect of NIR on the male reproductive system remains unknown. …”
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Low-cost nano biochar: a sustainable approach for drought stress mitigation in faba bean (Vicia faba L.) by Heba Ibrahim Abd El-Moaty, Heba Ibrahim Abd El-Moaty, Ali El-Dissouky, Amel F. Elhusseiny, Kareem M. Farag, Rasha Abu-Khudir, Rasha Abu-Khudir, Mayyadah Abdullah Alkuwayti, Najla K. Al Abdulsalam, Salwa M. Abdel Rahman

“…Surprisingly, the application of biochar increased soil water holding capacity and organic matter by 66% and 220%, respectively. …”
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Enhancing Gas Fermentation Efficiency via Bioaugmentation with <i>Megasphaera sueciensis</i> and <i>Clostridium carboxidivorans</i> by Clemens Hiebl, Dominik Pinner, Hannes Konegger, Franziska Steger, Dina Mohamed, Werner Fuchs

“…Gas fermentation aims to fix CO₂ into higher-value compounds, such as short or medium-chain fatty acids or alcohols. In this context, the use of mixed microbial consortia presents numerous advantages, including increased resilience and adaptability. …”
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Patterns of depression symptoms in relation to stressors and social behaviors during the COVID-19 pandemic among older youth and emerging adults in the United States. by Kevin M Cummins, Ty Brumback, Citlaly Corrales, Kate B Nooner, Sandra A Brown, Duncan B Clark

“…Substantial increases in depression at the outset of the pandemic were previously reported in NCANDA, a longitudinal sample of adolescents and young adults. …”
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Promuovere l’integrazione culturale: le istituzioni e il fenomeno migratorio by Giacomo Buoncompagni, Lucia D'Ambrosi

“… The current scenario, increasingly characterised by discursive practices and multi-ethnic social relations, requires institutions to play a more active role in strategies for the inclusion of immigrants. …”
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Hidden link between endocrine-disrupting chemicals and pediatric obesity by Min Won Shin, Shin-Hye Kim

“…The increasing prevalence of pediatric obesity has emerged as a significant public health concern. …”
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The impact of continuous connectivity on work-life balance by Ciprian GRIGORESCU, Adrian Gheorghe ZUGRAVU, Mihai TUDOR

“… In today’s organizational environment, work-life balance has become an essential component of motivational management strategies. In an increasingly competitive organizational environment, continuous activity at a sustained pace becomes a certain reality, especially in the context where ensuring the balance between professional and personal life becomes a major challenge for motivational management. …”
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THE MANAGEMENT OF KNOWLEDGE AND THE EXPERTISES DEVELOPED IN HIGHER EDUCATION by Arielly Kizzy Cunha, José Anderson Santos Cruz, José Luís Bizelli

“…In an increasingly enterprising labor universe, continuous improvement of the workforce to incorporate innovative technologies is a requirement that can make a difference for ingress and permanence in complex organizations. …”
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Providing aid to students with a migrant background in Polish schools by Aleksandra Gulińska

“…Results The process that has taken place in Polish education system in the context of the presence of migrant children and the increasing number of them in educational institutions was captured. …”
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Dental fear, anxiety, and phobia; causes, diagnostic criteria and the medical and social impact by Nadya Tsetsova Avramova

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Multidimensional Conceptual Approaches to Risk in Statutory Audit by Andrada-Mihaela STOICA

“…Given the rapid advancement of technology, the growing interconnection of global economies, and the evolving challenges faced by contemporary independent auditors, the topic of audit risk has gained increasing attention and significance. From this perspective, the objective of the present research is to identify and analyze, from a multidimensional standpoint, the conceptual approaches to risks in statutory audit. …”
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