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52541
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52542
A novel missense pathogenic variant c.9455T > G (p.L3152R) in CDH23 underlies autosomal recessive non-syndromic hearing loss
Published 2025-06-01“…This study aimed to identify the genetic cause of autosomal recessive non-syndromic hearing loss (ARNSHL) in a large Iranian family using next-generation sequencing and structural bioinformatics. Methods After a comprehensive clinical evaluation of a large family with a history of HL the GJB2 gene was sequenced, and 7 loci were screened through genetic linkage analysis. …”
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52543
Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study
Published 2024-03-01“…Despite extensive academic discussions, empirical data on these aspects, especially in the context of global health, remain limited.Methods To address this gap, we conducted a mixed-methods study focusing on research integrity and fairness. …”
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52544
Culinary connections: The mediating role of customer brand co-creation behavior in gastronomic and revisit intentions
Published 2025-01-01“…This study investigates the mediating role of customer brand co-creation behavior in the effect of gastronomic experience on revisit intention among Generation Z café visitors in Bali, Indonesia. Data were collected from 250 respondents via an online survey and analyzed using Partial Least Squares Structural Equation Modeling. …”
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52545
Longitudinal study of foot-and-mouth disease virus in Northern Nigeria: implications for the roles of small ruminants and environmental contamination in endemic settings
Published 2025-04-01“…Serum samples (n = 780) were also tested for the presence of antibodies against FMDV non-structural proteins. The proportion of FMDV RNA positive samples increased in all sample types collected in one LGA during the period when an FMD outbreak was reported in the same LGA. …”
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52546
Technology Anxiety in Virtual Reality Adoption: Examining the Impact of Age, Past Experience, and Cybersickness
Published 2025-01-01“…Using an extended Technology Acceptance Model (TAM), the research integrates age and past use as antecedents of TA and evaluates their influence on perceived ease of use (PEoU), perceived enjoyment (PENJ), and user attitudes. Data from 206 participants were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) following a VR pilgrimage experience. …”
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52547
A multi-species corridor between the Andean Amazonian and Amazon floodplain landscapes: prioritizing ecological connectivity areas for jaguar and threatened ungulates in the north-...
Published 2025-04-01“…However, there has been a lack of structural connectivity analysis in the Andean Amazonian and Amazon floodplain landscapes using a multi-species approach that considers predator–prey relationships among representative groups such as large felids and wild ungulate species. …”
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52548
Integrative analysis of saliva-derived exosomal proteome and lipidome for the diagnosis of esophageal squamous cell carcinoma
Published 2025-08-01“…The proteomic characteristics of ESCC were primarily manifested in immune responses, disruption of tissue structural homeostasis, and enhanced antifungal and antimicrobial humoral immune responses. …”
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52549
Optimized enrichment of murine blood–brain barrier vessels with a critical focus on network hierarchy in post-collection analysis
Published 2025-05-01“…Positioned between upstream arteries and downstream veins, these microvessels have unique structural features, such as the absence of vascular smooth muscle cells (vSMCs) and a relatively thin basement membrane, to facilitate highly efficient yet selective exchange between the circulation and the brain interstitium. …”
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52550
Addressing System Challenges in Mental Health Services Research for Youth in the Child Welfare System: Insights From the Foster Care Family Navigator Trial
Published 2025-03-01“…Systems‐level challenges that impacted proposed research trial design and data collection included: (1) Limited system staff time and compensation processes; (2) Staff training and knowledge; and (3) System disruptions. …”
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52551
A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion
Published 2025-08-01“…Further, φSa3int prophage domestication led to reduced phagocytosis implying φSa3int prophage mediates escape of S. aureus from human innate immunity. Our data further show that in addition to adding novel prophage‐encoded virulence, φSa3int prophage domestication also affects the expression of non‐prophage (bacterial) genes and suppresses expression of structural proteins of resident prophages. …”
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52552
Adsorptive Removal of Bisphenol A by Polyethylene Meshes Grafted with an Amino Group-Containing Monomer, 2-(Dimethylamino)ethyl Methacrylate
Published 2024-10-01“…The cycle of adsorption at pH 8.0 and desorption in a NaOH solution at 100 mM was repeated five times without loss or structural damage. These results indicate PE-g-PDMAEMA meshes can be used as a regenerative adsorbent for BPA removal from aqueous medium.…”
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52553
Caregivers’ lived experiences of childhood probable pneumonia through a gendered lens in western Kenya
Published 2025-07-01“…Contribution: This study’s findings emphasise the necessity of a holistic approach when developing intervention geared towards improving healthcare-seeking behaviour by considering the subtler factors beyond structural, social and economic influences.…”
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52554
Association Between Anatomic and Clinical Indicators of Injury Severity After Moderate-Severe Traumatic Brain Injury: A Pilot Study Using Multiparametric Magnetic Resonance Imaging
Published 2024-11-01“…Future larger studies could lead to the development of prediction models that integrate clinical data with anatomical (MRI), structural (DTI), and mechanical (MRE) changes caused by TBI, to inform prognosis and care planning.…”
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52555
Investigation of biomolecular dynamics by sensitivity-enhanced 1H–2H CPMAS NMR using matrix-free dynamic nuclear polarization
Published 2024-12-01“…Molecular dynamics of functional groups contain valuable information about structural properties and functional activities in biomolecules. …”
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52556
Modelling economics students’ use of ChatGPT and academic performance: insights from self-determination theory and epistemic curiosity
Published 2025-07-01“…The study used adapted scales of ICAP (i.e. measuring the use of ChatGPT), “desire to learn (DFL), self-efficacy (SE), beliefs about the future (BAF), epistemic curiosity (EP) and perceived academic performance (AP)”. Data were analysed using “partial least squares structural equation modelling (PLS-SEM) and fuzzy-set qualitative comparative analysis (fsQCA)”. …”
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52557
Changes of EEG beta band power and functional connectivity during spaceflight: a retrospective study
Published 2025-04-01“…Astronauts often report temporary neurological symptoms, such as disorientation, visual disturbances, and motor issues, potentially linked to structural and electrophysiological brain changes. To investigate this, electroencephalography (EEG) is a reliable tool to study brain activity in space, measuring oscillatory activity and functional connectivity (FC). …”
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52558
The interplay of coping styles and optimism/pessimism in shaping mental health in long-term survivors of malignant melanoma: a register-based cohort study
Published 2025-04-01“…We assessed sociodemographic and disease-related variables, optimism/pessimism (LOT-R), coping strategies (BC), depressive (PHQ-9), and anxiety symptoms (GAD-7). A structural equation model was conducted to analyse the hypothesized associations, modelling coping strategies (denial/self-blame, seeking external support, active coping) as mediators of the relationship of optimism/pessimism with depressive and anxiety symptoms. …”
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52559
Comparison of the Metabolic Profiles Associated with Protonitazene and Protonitazepyne in Two Severe Poisonings
Published 2025-06-01“…<b>Concusions</b>: To conclude, nitazene detection is highly challenging due to its extensive structural and metabolic diversity. Our findings highlight the contribution of the untargeted LC-HRMS screening approach and suggest that diagnostic product ions can serve as robust markers for nitazene identification.…”
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52560
SHAZAM: Self-Supervised Change Monitoring for Hazard Detection and Mapping
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