Agonist efficacy at the β2AR is driven by the faster association rate of the Gs protein by Clare R. Harwood, Clare R. Harwood, David A. Sykes, David A. Sykes, David A. Sykes, Theo Redfern-Nichols, Owen Underwood, Colin Nicholson, Colin Nicholson, Armin N. Khoshgrudi, Armin N. Khoshgrudi, Eline J. Koers, Eline J. Koers, Graham Ladds, Graham Ladds, Stephen J. Briddon, Stephen J. Briddon, Dmitry B. Veprintsev, Dmitry B. Veprintsev, Dmitry B. Veprintsev

“…The β2AR is a prototypical GPCR for structural and biophysical studies. However, the molecular basis of agonist efficacy at the β2AR is not understood. …”
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Multi-sphere coupling characteristics and gas-bearing controlling factors of calcareous shale reservoirs in the Yadu-Ziyun-Luodian Aulacogen under Early Carboniferous platform-basi... by Kun Yuan, Kun Yuan, Kun Yuan, Bing Feng, Gangquan Li, Zongan Xue, Zongan Xue, Zongan Xue, Tuo Lin, Tuo Lin, Tuo Lin, Xinxin Fang, Xiangcan Sun, Xiangcan Sun, Xiangcan Sun, Yinbo Xu, Yinbo Xu, Yinbo Xu, Fengzan Zheng

“…Integrating field geological surveys and well data, this study comprehensively evaluates the mineralogy, geochemistry, structural features, and gas content of these shales to decipher the key factors controlling gas enrichment, particularly in this tectonically complex area. …”
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Quantitative infrared detection methods for debonding in concrete-filled steel tubes during the hydration heat phase by Haonan Cai, Chongsheng Cheng, Hong Zhang, Jianting Zhou

“…Conducting rapid quantitative debonding detection after the completion of Concrete-filled steel tube (CFST) pouring is crucial for the timely identification and repair of potential structural issues. Currently, there is a lack of an infrared detection method that can perform quantitative detection specifically during the construction phase of CFST. …”
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Algorithm for analyzing randomness in point patterns by Tony Sampaio, Jorge Rocha, Cláudia M. Viana, Silvana Camboin, Fábio Marcelo Breunig, Edenilson Nascimento, Elaine de Cacia de Lima Frick

“…. • Automated scripts for structuring data, calculating expected and observed values, and applying the chi-square goodness-of-fit test for statistical analysis. • Advanced spatial analysis using chi-square goodness of fit coupled with and without Bonferroni correction, providing deeper insight into the study of the effect of spatial phenomena on the distribution of point events.…”
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The Interaction Between Self-Efficacy, Fear of Failure, and Entrepreneurial Passion: Evidence from Business Students in Emerging Economies by Elizabeth Emperatriz García-Salirrosas, Dany Yudet Millones-Liza, Rafael Fernando Rondon-Eusebio, Jorge Alberto Esponda-Pérez, Eulalia Elizabeth Salas-Tenesaca, Reinaldo Armas-Herrera, María Fernanda Zumba-Zúñiga

“…Scales from renowned researchers were used, which were translated and semantically validated in Spanish to measure the three variables. The data were analyzed using structural equation modeling with PLS. …”
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Using Steel Fiber-Reinforced Concrete Precast Panels for Strengthening in Shear of Beams: An Experimental and Analytical Investigation by Pitcha Jongvivatsakul, Linh V. H. Bui, Theethawachr Koyekaewphring, Atichon Kunawisarut, Narawit Hemstapat, Boonchai Stitmannaithum

“…An experimental program of RC beams strengthened by using SFRC panels, which were attached to both sides of the beams, is carried out to investigate the effects of fiber volume fraction, connection type, and number and diameter of bolts on the structural responses of the retrofitted beams. The current shear resisting model is also employed to discuss the test data considering shear contribution of SFRC panels. …”
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WETLAND AND BIOCULTURAL HERITAGE REGENERATION THROUGH THEMATIC ECOLOGICAL TOURISM PRACTICE: THE CASE OF PATAN SUB-DISTRICT, KHUN TAN DISTRICT, CHIANG RAI, THAILAND by Siripen YIAMJANYA, Kannapat KANKAEW, Bussaba SITIKARN, Parinya NAKPATHOM, Ali Mohsin Salim Ba AWAIN, Teerarat JABJAINAI

“…The analytic hierarchy process (AHP) was employed to rank the criteria for ecological tourism development. The structural equation modelling (SEM), as a quantitative approach, was used to foster the factors collected from the focus group. …”
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The impact of human resource management on irrigation and drainage management in Indonesia by Khalisah Hayatuddin, Asel Mohmuod, Ainur O. Ongdash, Seyed Saeed Asghari Zonouz, Shukur-Ali Ataev

“…Significant regional variations were observed, with Java demonstrating consistently higher performance scores compared to other regions. Structural equation modelling indicated that organisational culture (β = 0.412) and leadership style (β = 0.376) significantly influenced HRM effectiveness. …”
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Cerebral vascular malformations: pathogenesis and therapy by Qiheng He, Ran Huo, Yingfan Sun, Zhiyao Zheng, Hongyuan Xu, Shaozhi Zhao, Yang Ni, Qifeng Yu, Yuming Jiao, Wenqian Zhang, Jizong Zhao, Yong Cao

“…Traditionally viewed as congenital conditions with structural abnormalities, CVMs have been treated primarily through resection, embolization, and stereotactic radiosurgery. …”
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Conceptual principles of stimulating the attraction of investments in reconstruction projects of Ukraine by Vladyslav TEREMETSKYI, Volodymyr USTYMENKO, Olena KUREPINA, Kseniia TOKARIEVA, Mariana MALCHYK, Oleksii FAST, Viktor DOVHAN

“… The article’s purpose is to develop the conceptual basis for the formation of a complex investment mechanism combining legal, economic, and organizational investment stimulation tools for the reconstruction of Ukraine in the post-war period. System-structural, logical, dialectical, and dogmatic methods of scientific knowledge were applied, which enabled a thorough study of the regulatory framework, theoretical concepts, and empirical data in the field of investment activity regulation. …”
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Developing advanced datadriven framework to predict the bearing capacity of piles on rock by Kennedy C. Onyelowe, Shadi Hanandeh, Viroon Kamchoom, Ahmed M. Ebid, Fabián Danilo Reyes Silva, José Luis Allauca Palta, José Luis Llamuca Llamuca, Siva Avudaiappan

“…Abstract Developing accurate predictive models for pile bearing capacity on rock is crucial for optimizing foundation design and ensuring structural stability. This research presents an advanced data-driven framework that integrates multiple machine learning algorithms to predict the bearing capacity of piles based on geotechnical and in-situ test parameters. …”
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The influence of celebrity credibility, attractiveness, and social media influence on trustworthiness, perceived quality, and purchase intention for natural beauty care products by Md Shamim Hossain, Tarannum Islam, Md. Asaduzzaman Babu, Mehejabin Moon, Mehanaj Mim, Md Tamjid Ul Alam, Aditya Bhattacharjee, Most. Sadia Sultana, Mst. Mumtahina Akter

“…Drawing from the Stimulus-Organism-Response (SOR) Model, Theory of Planned Behavior (TPB), Source Credibility Theory (SCT), and Elaboration Likelihood Model (ELM), this study employs Partial Least Squares Structural Equation Modeling (PLS-SEM) to analyze the theoretical framework and model. …”
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Transcriptome Analysis Reveals the Requirement of the TGFβ Pathway in Ascidian Tail Regression by Wenjie Shi, Penghui Liu, Dongyu Yang, Yuan Zhuang, Boyan Lin, Bo Dong

“…Together with qRT-PCR verification, we identified four critical gene functional categories, including ion transporters/water channel, extracellular matrix structural constituent, extracellular matrix organization, and cell polarity establishment. …”
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Unveiling the role of frugal and digital capabilities in the financing of deep tech startups by Keully Cristynne Aquino Diógenes, Ana Carolina Calçado Lopes Martins, Claudia Pavani, Felipe Mendes Borini, Guilherme Ary Plonski

“…The hypotheses were tested using structural equation modeling through the Partial Least Squares (PLS-SEM) method. …”
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Numerical Evaluation of Abdominal Aortic Aneurysms Utilizing Finite Element Method by Konstantinos Kyparissis, Nikolaos Kladovasilakis, Maria-Styliani Daraki, Anastasios Raptis, Polyzois Tsantrizos, Konstantinos Moulakakis, John Kakisis, Christos Manopoulos, Georgios E. Stavroulakis

“…Towards this direction, Finite Element Models (FEMs) have emerged as a pivotal tool in medical research, particularly in simulating and understanding the complex fluid and structural behaviors of the circulatory system. Furthermore, this tool can be used for the calculation of certain risks regarding the function of the blood vessels. …”
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Diffraction studies of WS2 crystallographic ordering during laser MBE growth on Al2O3(0001) by E. Lobanova, M. Dorogov, V. Fedorov, T. Grasser, Y. Illarionov, I. Eliseyev, V. Davydov, A. Korovin, S. Suturin, N. Sokolov

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Lipids modulate the dynamics of GPCR:β-arrestin interaction by Antoniel A. S. Gomes, Michela Di Michele, Rita Ann Roessner, Marjorie Damian, Paulo M. Bisch, Nathalie Sibille, Maxime Louet, Jean-Louis Banères, Nicolas Floquet

“…Abstract β-arrestins are key molecular partners of G Protein-Coupled Receptors (GPCRs), triggering not only their desensitization but also intracellular signaling. Existing structural data point to high conformational plasticity of GPCR:β-arrestin interaction, with two completely different orientations between receptor and β-arrestin. …”
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Uncovering the state of knowledge about healthcare gentrification: a scoping review protocol by Isabelle Dufour, Christine Loignon, Martine Shareck, Nataly R Espinoza Suarez, Sophie Dupere, Philippe Apparicio, Julie Ouellet, Justine Pineault, Simone Amagnamoua, Marie-Claude Laferrière, Isabelle Wilson

“…To understand the complexity of healthcare access and to consider the socio-structural dimensions affecting equity in access to care, we aim to explore how healthcare gentrification has been described in the scientific literature and to document the reported relations between gentrification and healthcare access.Methods and analysis We will conduct a scoping review from data published from inception to September 2024 based on the methodology developed by Arksey and O'Malley (2005) and improved by Levac et al (2010). …”
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The Effect of AI Gamification on Students’ Engagement and Academic Achievement in Malaysia: SEM Analysis Perspectives by Nisar Ahmed Dahri, Noraffandy Yahaya, Waleed Mugahed Al-Rahmi, Latifah Almuqren, Abeer S. Almgren, Abdulrahman Alshimai, Ahmad Samed Al-Adwan

“…A quantitative approach was employed, combining online surveys and structural equation modeling (SEM) analysis with 290 students from Malaysia. …”
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Black gold, dark realities: Unpacking the socio-economic and environmental fallout of unauthorized oil extraction (Investigation in East Aceh, Indonesia) by Said Musnadi, Ridwan Ibrahim, Zuraida Zuraida, Maulidar Agustina, Mahdani Ibrahim

“…Using proportional random sampling techniques, 245 respondents were selected, representing owners and investors (9), tenant investors (18), workers/laborers (68), melters (6), public figures/community leaders (3), the community (138), and village government officials (3). Data were analyzed using structural equation modeling (SEM) with AMOS software. …”
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