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51721
Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition
Published 2025-04-01“…The central BAM subunit (BamA) is an attractive antibacterial target because its structure and cell surface localization are conserved, it catalyzes an essential reaction, and potent bactericidal compounds that inhibit its activity have been described. …”
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51722
Development and psychometric evaluation of the 12-item Polish version of the Pain Vigilance and Awareness Questionnaire
Published 2025-07-01“…None of the previously proposed models describing the factor structure of the PVAQ scale adequately fit the data. …”
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51723
Changes in subarctic Pacific phytoplankton communities over the last two decades
Published 2025-07-01“…Time series of remotely sensed data are now of sufficient length to begin to assess change in the ocean at large spatial and temporal scales. …”
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51724
Experimental investigation on thermal storage performance of double U-tube phase change thermal storage tank
Published 2025-09-01“…These findings provide valuable experimental data for optimizing the structure and operating parameters of large-scale PCTSTs.…”
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51725
Seasonality Has Greater Influence on Amphibian Cutaneous Mycobiome than Host Species
Published 2025-06-01“…The results showed that seasonal variation exerted a significantly stronger influence than host species on the fungal community structure (alpha diversity, beta diversity, species composition, abundance, and biomarkers). …”
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51726
Genome-Wide Association Study and Genomic Prediction of Essential Agronomic Traits in Diversity Panel of Soybean Varieties
Published 2025-05-01“…We assessed 15 agronomic traits under three distinct environments, noting substantial phenotypic variations in the panel and stable correlations among traits. The population structure analysis, based on genotyping-by-sequencing (GBS) data, revealed seven subpopulations within the panel and significant gene flows among these subpopulations. …”
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51727
EAM Integrated Widely Tunable DBR Lasers Based on InGaAlAs/InP MQWs
Published 2024-01-01“…At 25°, the electro-absorption modulator (EAM) of the device has a small signal modulation bandwidth exceeding 27 GHz, which is notably higher than the bandwidth for a TEML device having the same structure but InGaAsP MQW active material. At 25 Gb/s NRZ data modulation, to achieve 10E-10 bit error rate (BER), the power penalty after 5 and 10 km fiber transmission are 1 and 3 dB, respectively. …”
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51728
Temporal variability on Seagrass Cover and Species Composition in a Tourism Hotspot: A case study in Derawan Island
Published 2024-01-01“…This study aims to assess the resilience of the seagrass ecosystem on Derawan Island by examining temporal variability in seagrass cover and community structure. Permanent plots were established to monitor changes in seagrass cover and community composition. …”
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51729
An innovative thermal simulation study of microstructure improvement by delay forging during solidification
Published 2024-11-01“…Temperature and force data were collected using the Gleeble system for analysis. …”
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51730
Wheat dwarf virus and its impact on the 2020 harvest in some regions of Ukraine
Published 2021-03-01“…Visual diagnostics, enzyme-linked immunosorbent assay in double sandwich modification (DAS-ELISA), polymerase chain reaction, biometric, determination of yield and its structure, statistical data processing. Results. …”
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51731
Magnetic Bifunctional Ru-Enzyme Catalyst Allows for Sustainable Conversion of Cellulose Derivative to D-Sorbitol
Published 2025-05-01“…To optimize the nanobiocatalyst structure and composition, we first synthesized the biocatalyst, MNA-CSP-Cel (CSP stands for the CS layer cross-linked by TPP), as well as the nanocatalyst, MNA-CSP-Ru, and studied them in the one-step reactions of hydrolysis and hydrogenation, respectively. …”
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51732
Characterization and kinetic analysis of Vc1509, a NAD+ dependent deacetylase from Vibrio cholerae
Published 2025-01-01“…Vc1509 is a monomeric protein and harbours conserved secondary structure features of CobB. Our data show that Vc1509 is an active NAD+ dependent lysine de-acylase capable of targeting a broad range of acylated substrates, providing new insights into the enzymatic properties and substrate specificity of CobB bacterial deacetylases.…”
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51733
Identification of novel ABCB4 variants and genotype-phenotype correlation in progressive familial intrahepatic cholestasis type 3
Published 2024-11-01“…The study included statistical analysis of clinical information, genetic analysis, multi-species sequence alignment, protein structure modeling, and pathogenicity assessment. Machine learning techniques were applied to identify genotype-phenotype relationships. …”
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51734
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51735
Curlometer and gradient techniques: past and future applications
Published 2024-12-01“…Nevertheless, the techniques can be reliable in many magnetospheric regions where time stationarity is largely applicable, or when properties of the morphology can be assumed (for example, the expected orientation of underlying large-scale structure). Many magnetospheric regions have been investigated directly (illustrated here by the magnetopause, ring current and field-aligned currents at high and low altitudes), and options for variable numbers of spacecraft have been considered. …”
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51736
Association between tongue position and Dentofacial skeletal patterns: a simplified approach to tongue position assessment
Published 2025-06-01“…Abstract Background Tongue position plays a vital role in craniofacial development, influencing skeletal structure and dental alignment. This study aims to assess tongue position and investigate its relationship with various dentofacial skeletal patterns using a novel cephalometric analysis method. …”
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51737
Study on the role of tissue-specific and non-specific autoantibodies, matrix metalloproteinase-3 and neuron-specific enolase enzymes in the exacerbation of autoimmune thyroiditis
Published 2024-04-01“…Elevated titers of anti-DNA autoantibodies may indicate an aggravation of the autoimmune process due to cellular structure damage, resulting in gland dysfunction. The findings also suggest that metalloproteinase-3, a marker predicting thyroid tissue damage, may negatively impact the immune response induction, ultimately affecting the activity of neuron-specific enolase. …”
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51738
Creating and sustainable development of specialized centers as a way to improve quality of medical care
Published 2016-10-01“…The accumulated experience in the Center confirms the relevance of the creation of the structure of scientific and educational institutions specialized centers in which patients will be given to high-quality medical care.…”
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51739
Recyclable nano-CuI immobilized on UiO-66-NH2 coated with porous sodium alginate-polysulfonamide for synthesis of phenols
Published 2025-03-01“…FESEM images revealed spherical sodium alginate particles and TEM analysis indicated a core-shell structure. ICP data confirmed the anchoring of 0.67 mol% of copper iodide. …”
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51740
Validation of the World Health Organization’s Disability Assessment Schedule 2.0 for children with mental disorders in specialized health-care services
Published 2024-12-01“…Exploratory factor analysis revealed a six-dimensional structure, with gender-specific differences identified in functional impairment patterns.DiscussionThe study provides robust evidence supporting the utility and psychometric properties of the WHODAS 2.0 for assessing functional impairment in children and adolescents with mental disorders in Mexican psychiatric hospitals. …”
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