Age-dependent effect of environmental enrichment on the neural 3D chromatin interactome by Javier Gancedo-Verdejo, Rocío G. Urdinguio, Juan Ramón Tejedor, Raúl F. Pérez, Alfonso Peñarroya, Pablo Santamarina-Ojeda, Annalisa Roberti, Jennifer M. Kefauver, Carlota Álvarez-Díaz, Mar Rodríguez-Santamaría, José Luis Trejo, Laureano Tomás-Daza, Llorenç Rovirosa, Biola M. Javierre, Agustín F. Fernández, Mario F. Fraga

“…We also integrated liCHi-C data with RNA sequencing (RNA-seq) data to identify functional implications. …”
Get full text

A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA by Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen-Bo Chen, Jun-Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

“…Among them, hammerhead is the smallest and best characterized ribozyme. However, the structure and biochemical data of ribozymes have been disagreed on, making the understanding of its catalysis mechanism a longstanding issue. …”
Get full text

Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis by Qiannan Liu, Xiaoyan Lu, Yao Deng, Han Zhang, Rumeng Wei, Hongrui Li, Ying Feng, Juan Wei, Fang Ma, Yan Zhang, Xia Zou

“…Interestingly, we found dynamic changes with an increase Tn and a decrease T structure from early to mature developmental stages. …”
Get full text

Transcriptomics and proteomics provide insights into the adaptative strategies of Tibetan naked carps (Gymnocypris przewalskii) to saline-alkaline variations by Bingzheng Zhou, Ruichen Sui, Luxian Yu, Delin Qi, Shengyun Fu, Ying Luo, Hongfang Qi, Xiaohuan Li, Kai Zhao, Sijia Liu, Fei Tian

“…In the kidney, the tight junction formed dense structure in the renal tubules under lake water condition compared with the loose structure in freshwater. …”
Get full text

Investigation of genomic and pathogenicity characteristics of Streptococcus suis ST1 human strains from Guangxi Zhuang Autonomous Region (GX) between 2005 and 2020 in China by Weiming Kang, Mingliu Wang, Xueli Yi, Jianping Wang, Xiyan Zhang, Zongfu Wu, Yan Wang, Hui Sun, Marcelo Gottschalk, Han Zheng, Jianguo Xu

“…To enhance our understanding of S. suis ST1 population characteristics, we conducted an investigation into the phylogenetic structure, genomic features, and virulence levels of 73 S. suis ST1 human strains from GX between 2005 and 2020. …”
Get full text

Whole-genome resequencing reveals genetic differentiation and selection signatures among wild, local and commercial duck populations by Zhirong Huang, Liyun Zhang, Maojun Luo, Xumeng Zhang, Yunmao Huang, Yunbo Tian, Zhongping Wu, Xiujin Li

“…Objective The purpose of this study was to systematically analyze the population genetic structure and genetic diversity among wild, local and commercial populations using whole-genome sequencing data from 416 individuals of 22 duck breeds in China and to further explore genetic pathways and candidate genes associated with importantly economic traits. …”
Get full text

Rethinking of the Ornament in rural house (Case study: Ovan village in Qazvin) by Mohammad Yaser Mousapour

“…The first stage involves visiting and documenting rural dwellings and recording empirical evidence, and the second stage, including the review of literature related to decorating and rural housing, then analyzing and rational reasoning around the subject. The overall structure of this research is based on the qualitative research method. …”
Get full text

Layered Production Allocation Method for Dual-Gas Co-Production Wells by Guangai Wu, Zhun Li, Yanfeng Cao, Jifei Yu, Guoqing Han, Zhisheng Xing

“…However, due to fundamental differences between coal seams and tight sandstones in their pore structure, permeability, water saturation, and pressure sensitivity, significant variations exist in their flow capacities and fluid production behaviors. …”
Get full text

Salidroside ameliorates diabetic amyotrophy by targeting Caspase-3 to inhibit apoptosis by Hejie Wang, Wafa Yousaf, Abdul Haseeb, Ziyang Wang, Jiangang Zheng

“…Based on the crystal structure of the potential core protein, the complex structure model of the core target-SAL was created using molecular docking (XP mode of flexible docking), and the MMGBS analysis was carried out. …”
Get full text

Exercise-Induced Excessive Blood Pressure Elevation Is Associated with Cardiac Dysfunction in Male Patients with Essential Hypertension by Binfeng Xia, Pengyu Cao, Li Zhang, Huihui Huang, Rongyu Li, Xia Yin

“…Cardiopulmonary exercise testing (CPET) has been used to explore the blood pressure response and potential cardiovascular system structure and dysfunction in male patients with essential hypertension during exercise, to provide a scientific basis for safe and effective exercise rehabilitation and improvement of prognosis. …”
Get full text

DIAGNOSTIC AND TREATMENT CHARACTERISTICS OF LEPTOTHRICHOSIS OF THE ORAL MUCOSA by T.P. Skrypnіkova, P.M. Skrypnikov

“…According to the morphological data, the structure of the cell wall, antigenic structure, they are part of the opportunistic flora of the oral cavity. …”
Get full text

Effects of hydroxypropyl starch on intestinal health and transcriptome of geese by Pengfei Ye, Wenquan Liu, Xiaotong Tang, Mengxue Liu, Jingfan Han, Xiaoxue Wang, Jie Zhu, Xiaorong He, Xueqi Zhu, Mixia Cao, Lei Zhao, Qingchang Ren

“…Subsequent analysis revealed that HPS up-regulated the expression of genes associated with intestinal function (such as SLC5A12 and SLC5A8), structure (including NR5A2, IPMK), and uric acid metabolism (PDZK1). …”
Get full text

A STUDY OF THE INFLUENCE OF EXTRACELLULAR VESICLES ON THE MORPHOFUNCTIONAL STATE OF THE ENDOMETRIUM IN VITRO by Оксана Александровна Мелкозерова, Ирина Викторовна Крутинь, Александра Юрьевна Храмцова, Мария Валерьевна Улитко, Алсу Фармутовна Мустафина

“…When adding vesicles, no critical changes in the structure of the cell cytoplasm were detected, it remains homogeneous. …”
Get full text

Features of the vegetative state and arterial pressure level in children with chronic gastroduodenal pathology by A. S. Hotsulia

“…Hydrazides of 2-[4-R-5-((3'-methylxanthine-7'-yl)methyl)-1,2,4-triazole-3-ylthio]-ethane acid are synthesized by the interaction of the corresponding esters of 2-[4-R-5-((3'-methylxanthine-7'-yl)methyl)-1,2,4-triazole-3-ylthio]acetic acid with an aqueous hydrazine hydrate solution in ethanol. The structure of the obtained compounds is confirmed by the data of elemental analysis, 1H NMR spectroscopy, IR-spectrophotometry. …”
Get full text

Digital mapping of soil erodibility factor in response to land use change using machine learning models by Wudu Abiye, Orhan Dengiz

“…Among soil types, Calcaric Cambisols were identified as the most erosion-prone, while Lithic Leptosols were the least susceptible, attributed to differences in soil texture, structure, and organic matter content. Finally, the basin was classified based on soil erodibility classes. …”
Get full text

Beran casa 1864-1896 by Dedović Vukašin

Get full text

Features of “Inverted” Educational Resources for Distance Learning of Pupils by D. A. Barkhatova, A. L. Simonova, P. S. Lomasko, L. B. Khegay

“…Based on a theoretical analysis of psychological, pedagogical, methodological literature on the topic of research and modern statistical data demonstrating the level of readiness and motivation of students for independent distance learning, the paper describes the features of the structure and content of “inverted” educational resources, built taking into account the cognitive and psychosocial characteristics of modern “digital” generation. …”
Get full text

CENTER-ing Black voices: incorporating lived experience across the research process to advance equity in drug treatment and outcomes by Devin E. Banks, Maria E. Paschke, Kaytryn D. Campbell, Daje D. Bradshaw-Glenn, Rashmi Ghonasgi, Burton Barr, Arial Collins, Gerald Dennis, Keith Lofton, Alfred Long, Harriet Montgomery, Andreas Prince, Rachel P. Winograd

“…Academic staff dedicated to liaising with the CAB encouraged establishing structure and bylaws toward a self-governing CAB with decision-making power independent of agency partner and research teams. …”
Get full text

Morphology of traditional markets in Islamic countries based on the theory of transic lost space (Study sample: Zanjan and Istanbul markets) by Mohammad Behzadpour, Mahsa Razzaghi

“…<p class="MsoNormal" style="text-align: justify; line-height: normal; margin: 0in -28.35pt 10.0pt -28.35pt;"><span class="rynqvb"><span lang="EN" style="mso-ansi-language: EN;">Since ancient times, especially in Iranian cities, the market has been the main structure of the city and an urban interactive space in important economic, social and political fields.…”
Get full text

THE RESULTS OF THE SURVEY OF OBSTETRICIAN-GYNECOLOGISTS AND ASSESSMENT OF THEIR LEVEL OF PREPAREDNESS ON THE ISSUES OF QUALITY OF MEDICAL CARE by K. V. Yaroslavskiy, N. G. Petrova

“…One of the conditions for the provision of quality medical care is the involvement of all categories of medical personnel in the quality assurance process, which is impossible without clear knowledge of the theoretical aspects of this concept, including modern notions of conditions, structure, components, and criteria for assessing the quality. …”
Get full text