Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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A 50 s Quasiperiodic Oscillation in the Early X-Ray Afterglow of GRB 220711B by H. Gao, W.-H. Lei, S. Xiao, Z.-P. Zhu, L. Lan, S.-K. Ai, A. Li, N. Xu, T.-C. Wang, B. Zhang, D. Xu, J. P. U. Fynbo, K. E. Heintz, P. Jakobsson, D. A. Kann, S.-Y. Fu, S.-Q. Jiang, X. Liu, S.-L. Xiong, W.-X. Peng, X.-B. Li, W.-C. Xue

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Temperature Rise Characteristic of Circuit Breakers Based on New Environmentally Friendly Gas by Lihua ZHAO, Zhiyun WU, Zhiqiang YAN, Xiaolong HUANG, Wenjun NING, Shenli JIA

“…The arrangement of temperature sensors and the testing scheme are established, providing a data foundation for further studies on temperature rise characteristics. …”
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RAD-Seq-derived SSR markers: a new paradigm for genetic analysis and construction of genetically improved production populations in Pinus koraiensis by Pingyu Yan, Wanying Zhang, Junfei Hao, Xiaotian Miao, Jun Wu, Zixiong Xie, Zhixin Li, Lei Zhang, Hanguo Zhang

“…The SSR markers were subsequently employed to examine the genetic diversity and structure of the plus tree population. The genetic data were then integrated with multiyear cone production records from the population of plus trees, thus facilitating the construction of a production population. …”
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Leave as Fast as You Can: Using Generative AI to Automate and Accelerate Hospital Discharge Reports by Alex Trejo Omeñaca, Esteve Llargués Rocabruna, Jonny Sloan, Michelle Catta-Preta, Jan Ferrer i Picó, Julio Cesar Alfaro Alvarez, Toni Alonso Solis, Eloy Lloveras Gil, Xavier Serrano Vinaixa, Daniela Velasquez Villegas, Ramon Romeu Garcia, Carles Rubies Feijoo, Josep Maria Monguet i Fierro, Beatriu Bayes Genis

“…Future work should refine specialty-specific prompts to curb omissions, add temporal consistency checks to prevent outdated data propagation, and validate time savings and clinical impact in multi-center trials.…”
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Sofrimento laboral e estratégias de defesa referidas por técnicas de enfermagem de maternidades públicas [Distress at work and defensive strategies reported by nursing technicians... by Fernanda Alves Bittencourt Rodrigues, Jane Márcia Progianti, Juliana Amaral Prata, Elias Barbosa de Oliveira, Marina Nunes de Souza, Luísa dos Santos Belém

“…Method: in this exploratory, qualitative, descriptive study of 11 nursing technicians from public maternity hospitals in Rio de Janeiro, data were collected in May 2019 by semi-structured interviews, subjected to thematic content analysis, and discussed in the light of the Psychodynamics of Work. …”
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A prática dos enfermeiros obstetras egressos da especialização da Escola de Enfermagem Anna Nery [The practice of obstetric nurses with a degree from the specialization course at A... by Bianca Dargam Gomes Vieira, Maria Aparecida Vasconcelos Moura, Valdecyr Herdy Alves, Diego Pereira Rodrigues

“…This is a quantitative-qualitative study, whose subjects are 20 obstetric nurses with a degree from CEEO/EEAN, practicing in Rio de Janeiro, RJ, Brazil. Data collection was conducted through semi-structured interviews from March to September, 2008. …”
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Characteristic of Viral and Bacterial Contaminationin Objects of the Infection Hospital Environment of the Hospital for the Treatment of Patients with COVID-19 During the Pandemic... by I. A. Egorov, S. S. Smirnova, V. A. Mishchenko, I. V. Vialykh, A. Yu. Markarian, N. N. Zhuikov, S. V. Romanov, A. V. Ponomareva, I. V. Chistiakova, A. S. Kiliachina, O. Yu. Averianov, V. A. Smirnova, А. N. Bolshakova, E. V. Vernik, N. A. Pushkareva, A. V. Semenov

“…The opportunistic microflora structure was dominated by Enterococcus faecalis (38.1%), Klebsiella pneumoniaе (21.4%) and Escherichia coli (16.7%), which demonstrated a high level of resistance (to 3 or more groups of antibiotics).Conclusion. …”
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INTERCAMBIO DE NOTICIAS ENTRE BRASIL Y PORTUGAL A PARTIR DE UN ANÁLISIS CUANTITATIVO DE GOOGLE NEWS by Douglas Farias Cordeiro, Carlos Lopezosa, Javier Guallar, Jorge Pedro Sousa

“…ABSTRACT – This article investigates the exchange of news between Brazil and Portugal through a quantitative analysis of news aggregation in the Brazilian and Portuguese versions of Google News from February to April 2024. The data were extracted using scraping techniques and consolidated into a tabular structure, enriched with the use of artificial intelligence models for the categorization of the geographical origin of the news. …”
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EVERYDAY PRACTICES IN THE NEW MEDIA DISCOURSE (BY THE EXAMPLE OF COOKING SHOWS) / ПОВСЕДНЕВНЫЕ ПРАКТИКИ В ДИСКУРСЕ НОВЫХ МЕДИА (НА ПРИМЕРЕ КУЛИНАРНЫХ ШОУ)... by SIYUKHOVA AMINET M. / СИЮХОВА А.М.

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Association between Respiratory Function and Possible Sarcopenia in Community-Dwelling Elderly Population by SUN Zihan, FANG Leiwen, ZHOU Ting, LUO Sheng, YANG Xiaoling, LIU Juan, WANG Hongxing, YAO Jie

“…According to the 2019 Asian Working Group for Sarcopenia diagnostic criteria for possible sarcopenia, the participants were divided into two groups: the possible sarcopenia group (1,355 cases) and the non-sarcopenia group (2,183 cases). A structured questionnaire was utilized to collect demographic data, behavioral characteristics, dietary habits, and nutritional status. …”
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Fatores que potencializam a participação e comunicação dos estudantes de ensino superior na modalidade a distância / Factors that enhance the participation and communication of hig... by Paula Santos Orofino, Adson Nogueira Alves, Raphael Sigolo Ruas Gonçalves, Vitor da Silva Palacios, Mônica Cristina Garbin

“…Therefore, as specific objectives, the profile of students was also drawn in relation to the investigated sample, as well as a diagnosis made in undergraduate courses at a Brazilian State University about the current conception of students about the types of communication that occur during his academic training. background, revealing the frequency of use of communication tools and the frequency of interaction and level of influence between the actors involved.With the structuring and analysis of the data carried out, the following factors were identified as factors that enhance participation: expansion of synchronous interaction with the professor who authored the course; the need for a quicker return to messages that are posted on the forums; improving the administrative / didactic-pedagogical organization of the dissemination of lives; change in the schedule of lives or better sizing of schedules; and lives with exercise resolutions and on-call doubts. …”
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Study of the Effectiveness of Drugs Based on Molecular Complexes of Adenosine-polymer on the Model of Thermal Burn by E. D. Semivelichenko, A. A. Ermolaeva, V. V. Ponomarenko, A. V. Novoselov, G. A. Plisko, D. Yu. Ivkin, V. G. Antonov, V. E. Karev, I. A. Titovich, A. V. Eremin

“…This trend is actively developing, because the molecules forming MK, which has a certain composition and spatial structure, are preserved and can be released unchanged. …”
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Synergistic Effects of BaTiO₃ and MFe₂O₄ (M = Mn, Ni, Cu, Zn, and Co) Nanoparticles as Artificial Pinning Centers on the Performance of YBa<sub>2</... by Amjad S. Dair, Yassine Slimani, Essia Hannachi, Faten Ben Azzouz, Munirah A. Almessiere

“…An analysis of X-Ray diffraction (XRD) data of BT–MFe₂O₄-co-added YBCO samples showed the formation of an orthorhombic structure with <i>Pmmm</i> symmetry. …”
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Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care by Clare E Palmer, Emily Marshall, Edward Millgate, Graham Warren, Michael Ewbank, Elisa Cooper, Samantha Lawes, Alastair Smith, Chris Hutchins-Joss, Jessica Young, Malika Bouazzaoui, Morad Margoum, Sandra Healey, Louise Marshall, Shaun Mehew, Ronan Cummins, Valentin Tablan, Ana Catarino, Andrew E Welchman, Andrew D Blackwell

“…ObjectiveThis study aims to evaluate the engagement, effectiveness, and safety of this structured, evidence-based digital program with human support for mild, moderate, and severe generalized anxiety. …”
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FRAMED THEATRE: THEATRE HD AS A HYBRID FORM OF MEDIA / КАДРИРОВАННЫЙ ТЕАТР: THEATRE HD КАК ГИБРИДНАЯ ФОРМА МЕДИА by KOGUT NELLI A. / КОГУТ Н.А.

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Spatial Pattern and Evolutionary Characteristics of Settlements in Dianchi River Basin from the Perspective of Toponymy by Ying’ao WANG, Weijian HU, Wen PENG, Yuliang YANG

“…By constructing a coupling analysis framework of toponym semantics and spatial attributes, this research confirms the “spatio-temporal code” function of toponym in the process reconstruction of human settlements, and the capability to analyze multi-source heterogeneous data based on the aforesaid function provides a new analytical methodology for the research on watershed human settlements. …”
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Experimental Study on the Influence of Crack Penetration Rate on Strength Properties of Expansive Soil by HU Bo, WANG Shuai, SUN Hui, GENG Hong-bin, WANG Qing, ZHOU Hong-jun

“…Combined with the Mohr-Coulomb strength criterion and strength calculation methods for cracked surfaces, a composite strength analysis framework for the “soil block-crack” structure was established. Compared to traditional crack simulation methods, this technique enables precise control of crack geometry, effectively reproducing the crack development process and providing robust data support. …”
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Comparison of contact tracing methods: A modelling study by Joanna X.R. Tan, Lalitha Kurupatham, Zubaidah Said, Jeremy Chan, Kelvin Bryan Tan, Marc Ho, Vernon Lee, Alex R. Cook

“…To provide guidance on contact tracing for future preparedness, we assessed the effectiveness of contact tracing methods under varied environments using Singapore's population structure and COVID-19 as the disease model. Methods: We developed a transmission network model using Singapore's contact tracing data and the characteristics of COVID-19 disease. …”
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Factors associated with low HIV testing rate among people aged 15 to 65 years in Maroua 1 Health District, Far North Region of Cameroon by Godfroy Rostant Pokam Djoko, Alice Ketchaji, Juluis Visnel Foyet, Béatrice Tengoche, Oussena Nzie Vessah, Raoul Djiala Tawe Nsekalhye, Gwladys Kamwa Tchiemou, Nicole Modeste Ndohi, Dorcas Kamguem Keng, Amandine Koe Ngono

“…Methods A cross-sectional study was conducted among 808 participants aged 15 to 65 years living in the Maroua 1 Health District between September and December 2022. Data were collected by means of a non-probabilistic survey using a structured questionnaire sutured into socio-demographic characteristics, socio-cultural factors, and factors linked to the healthcare system. …”
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