SARS-CoV-2 Nsp14 binds Tollip and activates pro-inflammatory pathways while downregulating interferon-α and interferon-γ receptors by Naveen Thakur, Poushali Chakraborty, JoAnn M. Tufariello, Christopher F. Basler

“…ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 14 (Nsp14) possesses an N-terminal exonuclease (ExoN) domain that provides a proofreading function for the viral RNA-dependent RNA polymerase and a C-terminal N7-methyltransferase (N7-MTase) domain that methylates viral mRNA caps. …”
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The Intervened effect of place attachment on the relationship between community attachment and environmental behaviors (case study: Tajrish neighborhood) by Atousa Soleimani, Ahmad Nohegar

“…The participants were asked to fill out the research questionnaire whose reliability and validity were confirmed. The obtained data were statistically analyzed using the correlation analysis and structural equation modeling in SPSS-21 and AMOS-21. …”
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Manganese mitigates atrazine-induced oxidative stress and hepatorenal toxicity: insights from network pharmacology and in vivo experimentation by Solomon E. Owumi, Tella T. Adedayo, Joseph Chimezie, Bayode Oluwawibe, Harieme Agbarogie, Jesutosin O. Babalola, Oludare M. Ogunyemi, Uche O. Arunsi, Moses T. Otunla, Chioma E. Irozuru, Ahmad Altayyar, Eziuche A. Ugbogu

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The microbiologist's guide to metaproteomics by Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative

“…As the primary catalytic and structural components of microbiomes, proteins provide unique insights into the active processes and ecological roles of microbial communities. …”
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Investigating the Location-Spatial Effects of Urban Tourism on the Stability of the Urban Spatial System (Case Study: Region 3 of Isfahan City) by Mina Kazemi, Aboozar Vafaei, Rasool Heydari Sureshjani

“…A simple random sampling method was employed to select participants. For data analysis, a sample t-test was conducted using SPSS software, while Structural Equation Modeling (SEM) was utilized in AMOS software to assess the type and strength of relationships among the factors influencing the spatial effects of urban tourism on the stability of the city's spatial system. …”
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Fractional amplitude of low-frequency fluctuations during music-evoked autobiographical memories in neurotypical older adults by Teresa Lesiuk, Kaitlyn Dillon, Giulia Ripani, Ioannis Iliadis, Gabriel Perez, Bonnie Levin, Xiaoyan Sun, Roger McIntosh

“…In addition to a T1 structural scan, neuroimaging data were collected while participants listened to familiar music (MEAM retrieval) versus unfamiliar music.ResultsWhen listening to familiar compared to unfamiliar music, greater fALFF activation patterns were observed in the right parahippocampal gyrus, controlling for age and GMV. …”
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Public policy and sustainability: How green core competence, government trust, and policy satisfaction influence green R&D investments in the private sector by Fadi Abdelfattah, Mohammed Salah, Khalid Dahleez, Riyad Darwazeh, Hussam Al Halbusi

“…Grounded in Dynamic Capabilities Theory and Institutional Theory, it explores the relationship between Green Product Innovation Performance (GPIP), Green Process Innovation Performance (GPcIP), Green Core Competence (GCC), and Green Research and Development (R&D) Investments. Data collected from 214 top management personnel across diverse industries in Oman were examined via Structural Equation Modeling. …”
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In Vitro Antioxidant, Antithrombotic and Anti-Inflammatory Activities of Bioactive Metabolites Extracted from Kiwi and Its By-Products by Anastasia Maria Moysidou, Konstantina Cheimpeloglou, Spyridoula Ioanna Koutra, Vasileios Manousakis, Anna Ofrydopoulou, Katie Shiels, Sushanta Kumar Saha, Alexandros Tsoupras

“…Polar lipid structural analysis revealed a predominance of phospholipids with unsaturated fatty acids at the sn-2 position. …”
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Translation, cross-cultural adaptation, and psychometric properties of the Finnish version of the Malocclusion Impact Questionnaire (MIQ) by Lucas Arrais Campos, Terhi Kaikkonen, Kaisa Ylitervo, Leena Ylikontiola, Anna-Sofia Silvola

“…Psychometric properties were estimated using factorial validity (confirmatory factor analysis [CFA]), convergent validity (Average Variance Extracted [AVE]), and reliability (αordinal and ω). Structural Equation Model estimated the effect of demographic characteristics on malocclusion impact. …”
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Study of Lysozyme Activity in Bird Egg Whites by Fluorescence Polarization Assay Using Chitooligosaccharide Tracer by Liliya I. Mukhametova, Dmitry O. Zherdev, Anton N. Kuznetsov, Olga N. Yudina, Sergei A. Eremin, Vadim B. Krylov, Nikolay E. Nifantiev

“…Lysozyme activity in the egg whites of duck, goose, turkey, peacock, and ostrich eggs has not been detected by using the obtained chitooligosaccharide tracers, which may be related to the structural features of lysozyme in different bird species. …”
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Effect of atomic ratio of ions on the particle diffusion and permeability of carbon nanotubes in reverse electrodialysis process using molecular dynamics simulation by Ali B.M. Ali, Karwan Hussein Qader, Murtadha M. Al-Zahiwat, Narinderjit Singh Sawaran Singh, Soheil Salahshour, S. Mohammad Sajadi, Ali Mokhtarian

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A novel missense pathogenic variant c.9455T > G (p.L3152R) in CDH23 underlies autosomal recessive non-syndromic hearing loss by Ladan Sadeghian, Marziyeh Hoseinzadeh, Mohammad reza Pourreza, Saeed Khalili, Najmeh Fattahi, Mohammad Amin Tabatabaiefar

“…This study aimed to identify the genetic cause of autosomal recessive non-syndromic hearing loss (ARNSHL) in a large Iranian family using next-generation sequencing and structural bioinformatics. Methods After a comprehensive clinical evaluation of a large family with a history of HL the GJB2 gene was sequenced, and 7 loci were screened through genetic linkage analysis. …”
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Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study by Sandra Alba, Rutuja Patil, Martijn Wienia, Masja Straetemans, Francis Kombe, Gowri Gopalakrishna, Harry Coleman, Nima Yaghmaei, Joseph Bukulu Sempa, Jake D Mathewson, Hannah Kabelka, Preeti Sohoni

“…Despite extensive academic discussions, empirical data on these aspects, especially in the context of global health, remain limited.Methods To address this gap, we conducted a mixed-methods study focusing on research integrity and fairness. …”
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Culinary connections: The mediating role of customer brand co-creation behavior in gastronomic and revisit intentions by Ni Made Purnami, Ni Wayan Mujiati, Ayu Putu Laksmi Danyathi, Uswatun Siwi Kartika Sari, Desak Komang Dea Marcellina Putri Darmada

“…This study investigates the mediating role of customer brand co-creation behavior in the effect of gastronomic experience on revisit intention among Generation Z café visitors in Bali, Indonesia. Data were collected from 250 respondents via an online survey and analyzed using Partial Least Squares Structural Equation Modeling. …”
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Longitudinal study of foot-and-mouth disease virus in Northern Nigeria: implications for the roles of small ruminants and environmental contamination in endemic settings by Simon Gubbins, Emma Brown, Yiltawe Wungak, Olumuyiwa Oyekan, Adeyinka J. Adedeji, Sandra I. Ijoma, Rebecca B. Atai, Moses O. Oguche, Mark Samson, Banenat B. Dogonyaro, Fabrizio Rosso, Hayley Hicks, Britta A. Wood, Jemma Wadsworth, Nick Knowles, Donald P. King, Anna B. Ludi, Claire Colenutt, Andrew E. Shaw, Georgina Limon, David O. Ehizibolo

“…Serum samples (n = 780) were also tested for the presence of antibodies against FMDV non-structural proteins. The proportion of FMDV RNA positive samples increased in all sample types collected in one LGA during the period when an FMD outbreak was reported in the same LGA. …”
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Technology Anxiety in Virtual Reality Adoption: Examining the Impact of Age, Past Experience, and Cybersickness by Eman Al Khalifah, Ramy Hammady, Mahmoud Abdelrahman, Ons Al-Shamaileh, Mostafa Marghany, Hatana El-Jarn, Alyaa Darwish, Yusuf Kurt

“…Using an extended Technology Acceptance Model (TAM), the research integrates age and past use as antecedents of TA and evaluates their influence on perceived ease of use (PEoU), perceived enjoyment (PENJ), and user attitudes. Data from 206 participants were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) following a VR pilgrimage experience. …”
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A multi-species corridor between the Andean Amazonian and Amazon floodplain landscapes: prioritizing ecological connectivity areas for jaguar and threatened ungulates in the north-... by Federico Mosquera-Guerra, Sebastian Barreto, Juan D. Palencia-Rivera, Alexander Velásquez-Valencia, Hugo Mantilla-Meluk, Gustavo A. Bruges-Morales, Alex M. Jiménez-Ortega, Fernando Trujillo, Dolors Armenteras-Pascual

“…However, there has been a lack of structural connectivity analysis in the Andean Amazonian and Amazon floodplain landscapes using a multi-species approach that considers predator–prey relationships among representative groups such as large felids and wild ungulate species. …”
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Integrative analysis of saliva-derived exosomal proteome and lipidome for the diagnosis of esophageal squamous cell carcinoma by Wei Zhong, Jian Liu, Junhua Xie, Zhiyan Zhang, Zhiwen Gong, Zhixiang Yan, Qingdong Cao

“…The proteomic characteristics of ESCC were primarily manifested in immune responses, disruption of tissue structural homeostasis, and enhanced antifungal and antimicrobial humoral immune responses. …”
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Optimized enrichment of murine blood–brain barrier vessels with a critical focus on network hierarchy in post-collection analysis by Hanaa Abdelazim, Audra Barnes, James Stupin, Ranah Hasson, Carmen Muñoz-Ballester, Kenneth L. Young, Stefanie Robel, James W. Smyth, Samy Lamouille, John C. Chappell

“…Positioned between upstream arteries and downstream veins, these microvessels have unique structural features, such as the absence of vascular smooth muscle cells (vSMCs) and a relatively thin basement membrane, to facilitate highly efficient yet selective exchange between the circulation and the brain interstitium. …”
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Addressing System Challenges in Mental Health Services Research for Youth in the Child Welfare System: Insights From the Foster Care Family Navigator Trial by Marina Tolou‐Shams, Megan Ramaiya, Jannet L. Salas, Adrian Aguilera, Martha Shumway, Brian Borsari, Emily Dauria, Jill D. Berrick

“…Systems‐level challenges that impacted proposed research trial design and data collection included: (1) Limited system staff time and compensation processes; (2) Staff training and knowledge; and (3) System disruptions. …”
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