Machine learning enhanced metal 3D printing: high throughput optimization and material transfer extensibility by Yuanjie Zhang, Cheng Lin, Yuan Tian, Jianbao Gao, Bo Song, Hao Zhang, Min Wang, Kechen Song, Binghui Deng, Dezhen Xue, Yonggang Yao, Yusheng Shi, Kun Kelvin Fu

“…The high throughput methodologies are mostly on obtaining the printed samples and their structural and physical properties, while ML is used for data analysis by model building for prediction (optimization), and understanding. …”
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MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis by Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

“…In addition, transcriptomic analysis revealed structural changes specific to excitatory neurons with the A152T mutation. …”
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Genetically predicted white matter microstructure mediates the relationship between risk factors and lacunar stroke by Qing Ye, Jie Zhang, Li Zhang, Benyan Luo, Xiangming Ye, Min Wu, Wenshi Wang, Yue Zou, Douglas Neville, Kaisi Ren, Shuchang Zhong, Haiying Xiang

“…MD and ISOVF in the ALIC may serve as structural brain reserves and early biomarkers of hypertension-induced pathophysiology associated with lacunar stroke.…”
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Comparative Analysis of Plasma Protein Dynamics in Women with ST-Elevation Myocardial Infarction and Takotsubo Syndrome by Shafaat Hussain, Sandeep Jha, Evelin Berger, Linnea Molander, Valentyna Sevastianova, Zahra Sheybani, Aaron Shekka Espinosa, Ahmed Elmahdy, Amin Al-Awar, Yalda Kakaei, Mana Kalani, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Elmir Omerovic, Björn Redfors

“…Differential expression and functional significance were assessed. Data are accessible on ProteomeXchange, ID PXD051367. …”
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Cognitive gains and cortical thickness changes after 12 weeks of resistance training in older adults with low and high risk of mild cognitive impairment: Findings from a randomized... by Simona Kušleikienė, Gal Ziv, Wouter A.J. Vints, Erika Krasinskė, Milda Šarkinaite, Orgesa Qipo, Ivan Bautmans, Uwe Himmelreich, Nerijus Masiulis, Vida J. Česnaitienė, Oron Levin

“…Background: In this randomized controlled trial, we assessed the neuroprotective effect of a 12-week resistance training (RT) program on executive control and cortical thickness of the prefrontal, temporal, parietal, and central cortex, regions prone to structural decline in individuals with mild cognitive impairment (MCI). …”
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Clinical relevance of loss-of-function mutations of NEMO/IKBKG by Jin Wang, Kexin Shen, Hongxia Lou, Lina Zhou, Yunfei An, Xiaodong Zhao, Yuan Ding

“…Almost all cases of hyper-IgM occurred in patients with EDA-ID. Different structural domains correspond to symptoms with varying degrees of severity. …”
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Etiological mechanisms underlying the hazard factors and inflammatory bowel disease: a prospective cohort study by Yi Tao, Yongjia Li, Tianyi Zhou, Lei Zhao, Pan Li, Minghong Sun, Lijuan Zhang, Lihong Yang, Ting Chen, Xuemei Lian, Xiaoni Zhong

“…Finally, we constructed a structural equation model to elucidate the complex pathogenic mechanisms and interactions among genetic risks, lifestyle factors, dietary habits, comorbidities, and immune metabolism in the progression of IBD. …”
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Facial Expression Recognition and Digital Images Infosecurity for Prevention Care System Application in Sudden Infant Death Syndrome Monitoring by Chih-Te Tsai, Chia-Hung Lin, Hsiang-Yueh Lai, Yu-En Cheng, Ping-Tzan Huang, Neng-Sheng Pai, Chien-Ming Li

“…For image infosecurity testing, the number of pixel changing rate (NPCR), unified averaged changed intensity (UACI), and structural similarity index measurement (SSIM) were employed to evaluate the performances for encryption and decryption processes, ensuring confidentiality, recoverability, and availability of transmitted images. …”
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For-profit growth and academic decline: a retrospective nationwide assessment of Brazilian medical schools by Bruno B. Andrade, Bruno B. Andrade, Klauss Villalva-Serra, Klauss Villalva-Serra, Rodrigo C. Menezes, Rodrigo C. Menezes, Luiz F. Quintanilha, Katia de Miranda Avena, Katia de Miranda Avena

“…These patterns suggest a structural misalignment between the commercial logic of expansion and the core educational mission of medical training. …”
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EFFECTS OF PROLINE-RICH PEPTIDES OF THE INNATE IMMUNE SYSTEM ON DRUG-RESISTANT BACTERIAL STRAINS by M. S. Zharkova, P. M. Kopeykin, G. E. Afinogenov, D. S. Orlov, A. Yu. Artamonov, K. E. Safiullina, M. S. Sukhareva, E. V. Tsvetkova, B. L. Milman, A. G. Afinogenova, O. V. Shamova

“…Lack of hemolytic activity towards human red blood cells is an important benefit of the studied peptides when used at concentrations several times higher than those showing antimicrobial effects. The data obtained presume certain prospects for further investigations of proline-rich peptides, as well as their structural modifications, for the development of new combined drugs based on these compounds, in order to combat antibiotic-resistant microorganisms, e.g., medications for local applications, various components of medical devices, in particular, venous catheters, stents and wound dressings.…”
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The Middle to Late Triassic of Central Saudi Arabia with emphasis on the Jilh Formation. Part I: lithostratigraphy, facies and paleoenvironments, palaeontology and biostratigraphic... by Le Nindre, Yves-Michel, Vaslet, Denis, Vrielynck, Bruno, Krystyn, Leopold, Manivit, Jacques, Memesh, Abdullah, Davies, Roger Brett

“…Part II “Sequence stratigraphy, depositional and structural evolution, and regional correlations” exploits the results of Part I, providing a dynamic reconstruction and a renewed vision of the Middle to Late Triassic at the regional scale.The Jilh Formation at outcrop consists of a multilayer system of thinly bedded, mixed siliciclastics with subordinate carbonates and evaporites, representing non-marine to offshore settings. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…A physicochemical, structural, and molecular comparison was conducted with exosomes (EXOs) released from the same batch of cells. …”
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Metabolomic and Transcriptomic Analysis Revealed the Maturation Mechanism of White-Fleshed Strawberry by Linlin Xu, Xiaodong Chen, Qinglian Wang, Mizhen Zhao, Yushan Qiao, Zhaobiao Xie, Chuanwen Sun, Miao Sun, Weijian Cai

“…Further analysis revealed a co-expression of MYBs, bHLHs, NACs, and WRKYs with the structural genes mentioned. Overall, our findings uncovered a molecular mechanism regulating the maturation of white-fleshed strawberry, providing valuable insights for enhancing the flavor of white-fleshed strawberry through the gene-editing technique.…”
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Hypoxia-inducible factors: details create a picture. Part I. HIF-1 by G. A. Ignatenko, N. N. Bondarenko, S. V. Tumanova, T. S. Ignatenko, A. A. Kaluga, Ya. S. Valigun

“…The review presents a comparative analysis of scientific data on the structural and functional characteristics of subunits (HIF-1α and HIF-1β) of hypoxia-inducible transcription factor-1 (HIF-1). …”
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Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines by Ye. O. Karpun, N. M. Polishchuk

“…The aim of this work was to develop the antimicrobial and antifungal effects of the homologous series of S-alkyl-substituted 4-R-5-(((3-(pyridin-4-yl)-1H-1,2,4-triazole-5-yl)thio)methyl)-4Н-1,2,4-triazole-3-thiols and draw conclusions regarding the structural and functional relationship of the synthesized compounds. …”
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Experiment on physical and mechanical properties of tomato seedling pot for automatic vegetable transplanter by Liang Xifeng, Cai Yangyang, Wang Yongwei

“…However, automatic vegetable transplanter needs integrated knowledge and technology, the research on which should also combine the structural design with the physical and mechanical properties of vegetable seedling pot. …”
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Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm by Amjad Riaz, Ghulam S. Khan, Muhammad Zahid Tahir, Muhammad Yasir Zahoor, Hifz-ul-Rahman Hifz-ul-Rahman

“… Buffalo sperm suffer more cryoinjuries due to lipid peroxidation of their high structural polyunsaturated fatty acid contents than cattle. …”
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Extracorporeal Shock Waves Increase Markers of Cellular Proliferation in Bronchial Epithelium and in Primary Bronchial Fibroblasts of COPD Patients by Antonino Di Stefano, Roberto Frairia, Fabio L. M. Ricciardolo, Isabella Gnemmi, Antonella Marino Gammazza, Alessio Piraino, Francesco Cappello, Bruno Balbi, Maria Graziella Catalano

“…Chronic obstructive pulmonary disease (COPD) is due to structural changes and narrowing of small airways and parenchymal destruction (loss of the alveolar attachment as a result of pulmonary emphysema), which all lead to airflow limitation. …”
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Perceived social support and self-stigma as factors of COVID-19 booster vaccination behavior and intention via cognitive coping and emotion regulation among people infected with CO... by Xiaoying Zhang, Yiming Luan, Yihan Tang, Mason M. C. Lau, Yanqiu Yu, Jing Gu, Joseph T. F. Lau

“…The associations between the independent variables and BI-BV were tested by logistic regression analysis. A structural equation model (SEM) tested the indirect effects of the latent variables of self-stigma, active coping, and maladaptive emotion regulation between the latent variable of perceived social support and BI-BV. …”
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Undeliverable by design? How excessive internal medicine commitments are compromising Group 1 specialty training across the UK by Hasaan Rafique, Sadaf Hasaan, Neil Fisher

“…Conclusion: Our audit confirms that Group 1 training across one of the UK’s largest deaneries is not being delivered as intended. Without urgent structural reform, including enforcement of the 75:25 split, protection of specialty immersion time and reduced dependency on trainees to fill IM rotas, the UK risks producing a generation of consultants who are underprepared, undertrained and internationally uncompetitive. …”
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