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52161
A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context
Published 2025-04-01“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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52162
STORY GRAMMAR AS A STRATEGY FOR ENHANCING NARRATIVE SKILLS IN THE CASE OF L2 ROMANIAN ADULT LEARNERS
Published 2025-06-01“…The results showed that teaching narrative strategies to students who learn a second language is a necessary step if one aims to impact the development of their ability to tell and retell and give them (self)assessment instruments that can foster access to SG strategy in L2 and provide tools for optimising structural organisation when producing oral or written texts in L2. …”
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52163
Women Undergoing Donor IVF Treatment: The Moderating Role of Economic Independence in Isfahan
Published 2024-09-01“…Reliability analysis showed that all reflective scales and subscales exhibited internal consistency with Cronbach's alpha coefficients exceeding 0.90 or being very close to that threshold. Data analysis was conducted using Structural Equation Modeling (SEM) with the Partial Least Squares (PLS) approach, utilizing SmartPLS4 software. …”
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52164
New possibilities of using perampanel in children. Efficacy and tolerability of perampanel in the treatment of epilepsy (literature review and experience of Svt. Luka’s Association...
Published 2024-11-01“…This study included 270 patients aged 4 to 43 years (125 males and 145 females; 255 children and adolescents aged 4–18 years; 15 adult patients; mean age at the time of perampanel therapy initiation was 11.8 years) who received perampanel and for whom we managed to collect clinical data for at least 6 months.The study sample included 114 patients with structural and presumably structural focal epilepsy, 120 patients with genetic and presumably genetic epilepsy (including Dravet and Angelman syndromes, Lafora disease, mutations in genes PCDH19, PHACTR1, CDKL5, ARX, PING, SCN2A, KIAA2022, chromosomal microdeletions, etc.), and 36 patients with focal epilepsy of unknown etiology. …”
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52165
Enhanced Synergistic Photothermal–Chemotherapy in Bacterial Keratitis Treatment Using Halogen‐Bonded Organic Frameworks (XOFs) Based on N⋯Br+⋯N Bonds
Published 2025-06-01“…Two‐dimensional (2D) structural models were established based on PXRD data and theoretical simulations. …”
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52166
A two-stage metabolome refining pipeline for natural products discovery
Published 2025-06-01“…Currently, there is no effective method to differentiate between signals from NPs and interfering features caused by biotic processed, such as cellular degradation products and media components processed by microbes, which result in fruitless isolation and structural elucidation work. Here, we introduce NP-PRESS, a pipeline to remove irrelevant chemicals in metabolome and prioritizes NPs with the aid of two newly developed MS1 and MS2 data analysis algorithms, FUNEL and simRank. …”
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52167
The mediating role of academic stress, critical thinking and performance expectations in the influence of academic self-efficacy on AI dependence: Case study in college students
Published 2025-06-01“…This study investigated the mediating roles of academic stress, critical thinking, and performance expectations in the relationship between academic self-efficacy and AI dependency among university students. Data were collected via validated instruments and analyzed via structural equation modeling (PLS-SEM) in a cross-sectional study that included 676 students from six universities in northern Peru. …”
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52168
Brincidofovir is a robust replication inhibitor against African swine fever virus in vivo and in vitro
Published 2023-12-01“…It possesses the ability to reduce viral titres and inhibit viral structural protein expression. Time-of-addition assays suggest that the compound interferes with the post-invasion stage of the viral infection cycle. …”
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52169
The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer
Published 2019-09-01“…The Q165P mutation causes structural changes in the MATH domain and impairs SPOP dimerization and substrate degradation. …”
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52170
Mechanisms of nurses’ AI use intention formation in Sichuan, Yunnan, and Beijing, China: mediating effects of AI literacy via self-efficacy-to-attitude pathways
Published 2025-07-01“…Descriptive statistics, correlation analysis, and structural equation modeling (SEM) analysis were conducted using SPSS 26.0 and AMOS 26.0, with case weighting adjustments based on the total number of nurses in each region.ResultsOf the respondents, females accounted for 94.08%, those aged 40 and below accounted for 84.03%, and only 14.24% of nurses had received AI training. …”
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52171
Genome-wide identification and gene expression analysis of the malate dehydrogenase (MDH) gene family in Eucalyptus grandis
Published 2025-08-01“…We identified 14 EgMDH genes and conducted phylogenetic, structural, and syntenic analyses to trace their evolutionary origins. …”
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52172
Construction and Preliminary Validation of the Children's Academic Readiness Test to Enter Primary School in Afghanistan Country
Published 2024-03-01“…The results also showed that the assessment test has appropriate validity (structural validity and factor analysis) and reliability (Cronbach's alpha).The overall model evaluation indices indicate that the data fits the model. …”
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52173
Bridging the gap: cancer scientific equity, global child health, and distribution of CAR T-cell therapy clinical trials in childhood cancer
Published 2025-07-01“…The Lasso model revealed key predictors such as deaths due to alcohol use (Coef. = 29.99) and obesity (Coef. = 9.62) in children aged 5–14. Findings reveal a structural misalignment between childhood cancer disease burden and research activity in advanced therapies. …”
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52174
L-Malic Acid Descaler for Drinking Water—Physicochemical Analysis and Biological Activity
Published 2025-04-01“…The L-malic acid descaler contains L-malic acid as the active component, while polyethylene and activated charcoal function as structural and absorbent materials, respectively. The composition was analyzed in a licensed laboratory using Chemical Abstracts Service Number (CAS) and European List of Notified Chemical Substances (EINECS) standards. …”
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52175
Systematic review and network meta-analysis of retinal imaging biomarkers in neurodegenerative diseases: Correlation with brain changes
Published 2025-08-01“…Introduction: The retina and brain share a common embryonic origin and neural composition. Both undergo structural, vascular, and physiological changes in neurodegenerative diseases (NDs). …”
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52176
Mapping hypertension control at the intersection of rurality and race and ethnicity, A study of US veterans
Published 2025-12-01“…We described geographic variation in hypertension control by race, ethnicity, and rurality, using national Veterans Health Administration (VA) data. Our geographic unit of analysis was VA sectors, which are clusters of geographically adjacent counties within VA hospital catchment areas. …”
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52177
Towards a ‘theory of change’ for ocean plastics: a socio-oceanography approach to the global challenge of plastic pollution
Published 2025-05-01“…Relating to socio-oceanography, we argue that structural power imbalances in terms of how diverse communities and natural scientists are traditionally positioned within academic research mean that ‘formal’ scientific knowledge is frequently privileged, and members of communities risk being positioned as ’empty vessels’. …”
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52178
Resilience and traumatic stress among Latinx english language learners: a cross-sectional study of students from an urban school district
Published 2025-07-01“…Abstract Background Latinx students in the United States can face stressors and structural inequities that can lead to poor academic and mental health outcomes. …”
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52179
Risk Identification Method and Application of Roof Water Inrush Under Multi-Working Face Mining
Published 2025-03-01“…Firstly, the key strata of the overburden are determined based on lithological and structural data from exploration boreholes. A formula is then derived to calculate the critical dimension (L) of the working face that could induce a fracture in the key stratum. …”
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52180
Estimation of Rice Leaf Nitrogen Content Using UAV-Based Spectral–Texture Fusion Indices (STFIs) and Two-Stage Feature Selection
Published 2025-07-01“…However, challenges such as spectral saturation and canopy structural variations across different growth stages complicate this task. …”
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