Functional work disability from the perspectives of persons with systemic lupus erythematosus: a qualitative thematic analysis by Behdin Nowrouzi-Kia, Aaron S. Howe, Anson Li, Jeremy Tan, Natalia Saade-Cleves, Kevon Jules, Malak Sadek, Ali Bani-Fatemi, Antonio Avina-Zubieta, Mary T. Fox, William Shaw, Derek Haaland, Janet Pope, Paul R. Fortin, Kathleen S. Bingham, Christine Peschken, Jennifer Reynolds, Catherine Ivory, Dafna D. Gladman, Murray B. Urowitz, Jorge Sanchez-Guerrero, Lily S. H. Lim, Stephanie Keeling, Patti Katz, Mahta Kavkan, Dennisse Bonilla, Wils Nielsen, Zahi Touma

“…Methods With the objective of creating an SLE-related functional profile rooted in work disability (WD) prevention, 46 SLE patients were purposively recruited from Canadian medical centres. Through semi-structured interviews guided by a WD prevention framework, factors associated with WD and lived experiences of SLE-related WD were qualitatively explored. …”
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Effects of vaping on physical and mental health in at-risk populations (VAPE): mixed-methods study of motivations for and perspectives on vaping in patients with opioid use disorde... by Alessia D’Elia, Balpreet Panesar, Nitika Sanger, Laura O’Neill, Tea Rosic, Leonora Regenstreif, Kevin Park, Claire de Oliveira, David C. Marsh, Luciano Minuzzi, Lehana Thabane, Zainab Samaan

“…Method A convergent mixed-methods study design was used, and individual, semi-structured interviews were conducted with 41 individuals with OUD who were receiving medication for OUD and also vaped. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…It is theory driven because it uses evidence to iteratively develop and test structurally coherent explanations (i.e. theories) of complex interventions. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…Despite studies conducted, there are no unambiguous data showing how IMQ affects the condition of tumor blood vessels. …”
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Evaluating acceptability and experiences of pregnant women at high risk of developing gestational diabetes who take part in antenatal intervention trials: a qualitative systematic... by Gözde Sultan Çakır, Manar Abduljalil Bakhsh, Ola F. Quotah, Olivia Righton, Catherine V. George, Lucilla Poston, Sara L. White, Angela C. Flynn, Zoë Bell

“…All were pilot RCTs using semi-structured interviews in high-income countries (UK n = 3, USA n = 1). …”
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Rationale and design of a large trial of perioperative ketamine for prevention of chronic post-surgical pain by Philip J. Peyton, Sabine Braat, Anurika De Silva, David Story, Lisbeth Evered, Paul S. Myles, Matthew Chan, Stephan Schug, Malcolm Hogg, Alex Holmes, Sofia Sidiropoulos, Kate Leslie

“…Incidence of pain in the area of the index surgery is measured by structured telephone interview at 3 months (primary trial endpoint) and 12 months. …”
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Navigating the decision landscape: understanding interstitial cystitis/bladder pain syndrome patients’ motivations and medical support needs for fecal microbiota transplantation: a... by Hongyuan Liu, Yaodi Wei, Peng Jiang, Siyu Fan, Yu Zhao, Zhi Li, Shiyu Wang, Na Zhang, Junjie Zhi, Qun Wei, Yifeng Gu, Bihong Yang, Ninghan Feng, Yufan Wu, Fengping Liu

“…Data analysis was conducted using a thematic approach. …”
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Eco-anxiety, climate concern, and fatalistic outlooks: Insights from U.S. crisis text conversations on climate distress by Jennifer D. Runkle, Kelsey Herbst, Sophie Ryan, Kelly Sewell, Ashley Mallare, Ian Berry, Emma Getz, Arden McKee, Martie P. Thompson, Margaret M. Sugg

“…A comprehensive codebook was developed, incorporating predetermined and emergent codes for climate change exposures, crisis flags, emotional responses, and special topics. Using a structured, iterative thematic analysis approach that combined deductive and inductive methods, the study identified and categorized emerging themes. …”
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Farmers’ knowledge, perceptions, and practices on animal trypanosomosis and the tsetse fly vector: A cross-sectional study around Kenya’s Arabuko-Sokoke Forest Reserve at the lives... by Joel L Bargul, Erick K Serem, Osman A Abdullahi, Moses M Ngari, David M Mburu

“…Methods: A cross-sectional study was conducted during November and December 2017 to collect data from 404 randomly selected cattle-rearing households using a structured questionnaire. …”
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Co-designing a peer support programme for carers of people treated under the Mental Health Act: views from stakeholders by Imogen Wells, Kelly Wintsch, Abigail G-Medhin, Brynmor Lloyd-Evans, Steve Gillard, Rose McCabe, Mohamed Yaasir Mohamudbucus, Candelaria Mahlke, Katharina Nagel, Zhenreenah Muhxinga, Swaran Singh, Stefan Priebe, Domenico Giacco

“…Conclusions These findings highlight the need for structured training for peer supporters and a flexible, accessible peer support programme for carers. …”
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Care coordinator delivered Method of Levels therapy for people reporting first-episode psychosis: Experiences and views of service user, care coordinator, and team manager particip... by Robert Griffiths, Sara Tai, Susan Ormrod, Natalie Welsh, Adam Jones, Jasper Palmier-Claus, James Dixon, Alison Dawber, Karina Lovell

“…It also sought to understand participants’ experiences of the MOL training and supervision programme, and to identify any barriers that might impact on the implementation of the approach in routine practice. Methods Semi-structured interviews and focus groups were conducted with service users (n = 14), care coordinators (n = 6), and team managers (n = 6) from early intervention in psychosis services. …”
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Effects of caloric restriction and exercise-induced weight loss on physiological dysregulation in postmenopausal women: The mediating role of fat mass and adipose tissue distributi... by Éloïse Routhier, Martin Brochu, Alan A. Cohen, Denis Prudhomme, Ahmed Ghachem

“…Objectives: 1) To evaluate the impact of a 6-month caloric restriction (CR) program, either alone or in combination with structured exercise (CR + Ex), on PD. 2) To investigate whether changes in adipose tissue quantity and distribution mediate the effects of these interventions on PD. …”
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Antibiotic Consumption Patterns in Urban Coari, Amazonas: High Azithromycin Use and COVID-19-Related Prescriptions by Rodrigo Silva Marcelino, Edivã Bernardo da Silva, Abel Santiago Muri Gama, Ananias Facundes Guimarães, Silvia Regina Secoli, Albert Figueras

“…<b>Methods</b>: A cross-sectional study was conducted between October and November 2021 in the urban area of Coari. 394 adults were interviewed using a structured questionnaire. Data on antibiotic use, sociodemographic factors, health service access, and self-reported illnesses were collected. …”
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The role of offensive and creative priming videos in enhancing youth football players’ performance during small-sided games by Diogo Coutinho, Diogo Coutinho, Bruno Gonçalves, Bruno Gonçalves, Sara Santos, Sara Santos, Sigrid Olthof, Rafael Ballester Lengua, André Roca, Bruno Travassos, Bruno Travassos, Bruno Travassos

“…Coaches can leverage offensive priming to improve structured passing and positioning, while creative priming may inspire exploratory movements and innovative shooting attempts.…”
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Transition from child to adult health services for young people with cerebral palsy in Ireland; implications from a mixed-methods study [version 2; peer review: 2 approved] by Owen Hensey, Amanda Breen, Aisling Walsh, Mary Owens, Claire Kerr, Sebastian Koppe, Grace Lavelle, Meriel Norris, Michael Walsh, Jennifer M. Ryan, Thilo Kroll, Jennifer Fortune

“…Methods A convergent parallel mixed-methods study was conducted. Data were collected from people with cerebral palsy aged 16–22 years, parents, and health professionals using surveys and semi-structured interviews, which were both informed by a framework of nine key transition practices. …”
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Investigation of an extensive outbreak of HIV infection among children in Sindh, Pakistan: protocol for a matched case–control study by Victoria Simms, Rashida Ferrand, Baseer Achakzai, Iqbal Azam, Amna R Siddiqui, Apsara Ali Nathwani, Syed H Abidi, Syed Faisal Mahmood, Sobiya Sawani, Abdul M Kazi, Aneeta Hotwani, Sikander Ali Memon, Jamila Soomro, Saqib Ali Shaikh, Quaid Saeed, Palwasha Khan, Fatima Mir

“…Following written informed consent from the guardian, a structured questionnaire will be administered to collect data on sociodemographic indices and exposure to risk factors for parenteral, vertical and sexual (only among those aged above 10 years) HIV transmission. …”
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Optimising Paediatric Transition to Intensive Care for Adults (OPTICAL): study protocol for a mixed method study by Padmanabhan Ramnarayan, Louise Rose, Julie Taylor, Christina Pagel, Jo Wray, Sarah E Seaton, Kate Oulton, Sonya Crowe, Rum Thomas, Qi Huang, Paul R Mouncey, Katherine Malbon, Anjalika Mallick, Charmaine Kohn, Sue Ben Abraham, Clare Windsor

“…To do this, we will: (1) link and analyse UK national data (years 2017–2024) on paediatric and adult ICU admissions, hospital inpatient, outpatient and emergency care visits and survival status, to determine the clinical characteristics and healthcare resource utilisation from teenage years to early adulthood of people admitted to an ICU as a young person (admission aged 14 and 15), and how these relate to ICU admissions after age 16; (2) conduct semistructured interviews, online forums and surveys with TYA patients, carers and health professionals to understand their experience of transition in ICU services; and (3) synthesise these strands of evidence and use a structured process of stakeholder engagement to propose potential targeted improvements as appropriate.Ethics and dissemination This study was approved by the East of England - Cambridge South Research Ethics Committee on 1 August 2024 (research ethics committee number 24/EE/0108), and the Health Research Authority Confidentiality Advisory Group (CAG) on 7 October 2024 (CAG number 24/CAG/0068). …”
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Vulvovaginal candidiasis: knowledge, practices and occurrence among pregnant women receiving antenatal care in a teaching hospital, Ghana by Florence Shine Edziah, Florence Shine Edziah, Princess Ruhama Acheampong, Philip Apraku Tawiah, Cedric Dzidzor Amengor, Godsway Edem Kpene, Grace Otobea Amponsah, Priscilla Appiah Baffoe, Georgina Korankye, John Gameli Deku

“…This study assessed the knowledge, practices and occurrence of Vulvovaginal candidiasis among pregnant women accessing antenatal care at a teaching hospital in Ghana.MethodsA cross-sectional study was conducted among 336 pregnant women receiving antenatal care at the Ho Teaching Hospital. A structured questionnaire was used to assess their knowledge of the infection and practices on vaginal hygiene. …”
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The experience of immersive virtual reality in patients with heart failure during cardiac rehabilitation: a qualitative study by Valentina Micheluzzi, Valentina Micheluzzi, Gavino Casu, Gavino Casu, Francesco Burrai, Antonella Canu, Antonio Sircana, Pierluigi Merella, Pierluigi Merella, Angelo Laconi, Angelo Laconi, Andrea Chelo, Andrea Chelo, Piero Cozzula, Michela Piredda, Ercole Vellone, Ercole Vellone

“…The intervention group experienced iVR in natural settings, while the control group received standard care. Semi-structured individual interviews were conducted in person after the intervention group’s eighth rehabilitation session. …”
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Strengthening neonatal care through ward assistants: a Kenyan case study in enhancing infection prevention and control practices by Michuki Maina, Nancy Odinga, Vincent Kagonya, Gloria Ngaiza, Sebastian Fuller, Onesmus Onyango, Caroline Waithira, Dorothy Oluoch, David Gathara, Peter Mwangi, Loise Mwangi, Penina Musyoka, Lucy Kinyua, Lydia Thuranira, Virginia Njoroge, Ngina Mwangi, Zainab Kioni, Mike English, Edna Mutua

“…Methods This study employed a mixed methods approach in four public neonatal units in Kenya to assess the impact of deploying ward assistants on IPC practices. Data collection included structured and unstructured observations, in-depth interviews, and focus group discussions with healthcare workers and caregivers. …”
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