Genome-wide analysis of the laccase gene family in tossa jute (Corchorus olitorius): insights into stem development, lignification, and responses to abiotic stress by Deepak Kumar Jha, Deepak Kumar Jha, Subhadarshini Parida, Seema Pradhan, Nrisingha Dey, Shuvobrata Majumder

“…Further expression analysis in X-ray-induced bfs (bast fibre-shy) mutant tossa jute lines suggested that ColLAC34 is involved in both lignification and structural development, while ColLAC22, ColLAC40, and ColLAC46 play key roles in lignification. …”
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Mapping grey matter and cortical thickness alterations associated with subjective cognitive decline and mild cognitive impairment among rural-dwelling older adults in China: A popu... by Ziwei Chen, Qianqian Xie, Jiafeng Wang, Yan Wang, Huisi Zhang, Chunyan Li, Yongxiang Wang, Lin Cong, Shi Tang, Tingting Hou, Lin Song, Yifeng Du, Chengxuan Qiu

“…Background: The structural brain alterations for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are poorly defined. …”
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Design and rationale of MYOFLAME-19 randomised controlled trial: MYOcardial protection to reduce post-COVID inFLAMmatory heart disease using cardiovascular magnetic resonance Endpo... by Valentina O. Puntmann, Dietrich Beitzke, Andreas Kammerlander, Inga Voges, Dominik D. Gabbert, Marcus Doerr, Bishwas Chamling, Biykem Bozkurt, Juan Carlos Kaski, Erica Spatz, Eva Herrmann, Gernot Rohde, Philipp DeLeuw, Lenka Taylor, Christine Windemuth-Kieselbach, Cornelia Harz, Marta Santiuste, Laura Schoeckel, Juliana Hirayama, Peter C. Taylor, Colin Berry, Eike Nagel

“…ABSTRACT: Background: Cardiac symptoms due to postacute inflammatory cardiac involvement affect a broad segment of previously well people with only mild acute coronavirus disease 2019 (COVID-19) illness and without overt structural heart disease. Cardiovascular magnetic resonance (CMR) imaging can identify the underlying subclinical disease process, which is associated with chronic cardiac symptoms. …”
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Type 2 gene expression signature in severe asthma associates with more advanced airway remodeling by Bogdan Jakiela, Karolina Górka, Iwona Gross‐Sondej, Sławomir Mikrut, Krzysztof Okoń, Piotr Sadowski, Anna Andrychiewicz, Hanna Plutecka, Tomasz Stachura, Grażyna Bochenek, Stanisława Bazan‐Socha, Krzysztof Sładek, Jerzy Soja

“…Severe asthma is linked to reduced ventilatory function due to airway structural changes. This study compared the extent of airway remodeling in different immunological endotypes of asthma. …”
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Exploring the relationship between intrinsic capacity and social participation in healthy ageing: Evidence from Singapore by Grace Cheong, William Tov, Robin Wai Munn Choo, Micah Tan, Lay Khoon Lau, Wee Shiong Lim, Yew Yoong Ding, Paulin Tay Straughan

“…We performed structural equation modelling to compare the direct and indirect effects (mediated by IADLs) of intrinsic capacity on social participation. …”
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Endothelial Damage in Sepsis: The Interplay of Coagulopathy, Capillary Leak, and Vasoplegia—A Physiopathological Study by Gianni Turcato, Arian Zaboli, Lucia Filippi, Alessandro Cipriano, Paolo Ferretto, Michael Maggi, Fabrizio Lucente, Massimo Marchetti, Lorenzo Ghiadoni, Christian J. Wiedermann

“…The Sepsis-Induced Coagulopathy (SIC) score, serum albumin (as a surrogate for capillary leak), and Total Peripheral Resistance Index (TPRI) (as a surrogate for vasoplegia) were assessed. Structural Equation Modeling (SEM) explored the relationship between variables, hypothesizing a common latent factor (endothelial damage). …”
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THE ARTISTIC POTENTIAL OF CHORAL CONDUCTING IN CONTEMPORARY UKRAINE by Lyudmyla SHUMSKA, Yuliia PUCHKO-KOLESNYK, Lyudmyla KOSTENKO, Oleksandr VILA-BOTSMAN, Olha MARTYNOVSKA

“…As part of the methodological approach to the study, a comparative and structural analysis was applied, including the processing of statistical data on choral performances on the YouTube platform, as well as an analysis of the use of modern technologies in Ukrainian music institutions based on open sources. …”
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Simulation of Image-Guided Microwave Ablation Therapy Using a Digital Twin Computational Model by Frankangel Servin, Jarrod A. Collins, Jon S. Heiselman, Katherine C. Frederick-Dyer, Virginia B. Planz, Sunil K. Geevarghese, Daniel B. Brown, William R. Jarnagin, Michael I. Miga

“…Healthcare digital twins (DTs) are anatomically one-to-one biophysical models constructed from structural, functional, and biomarker-based imaging data to simulate patient-specific therapies and guide clinical decision-making. …”
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Deep learning-based computational approach for predicting ncRNAs-disease associations in metaplastic breast cancer diagnosis by Saleem Ahmad, Imran Zafar, Shaista Shafiq, Laila Sehar, Hafsa Khalil, Nida Matloob, Mehvish Hina, Sidra Tul Muntaha, Hamid Khan, Najeeb Ullah Khan, Samreen Rana, Ahsanullah Unar, Muhammad Azmat, Muhammad Shafiq, Yousef A. Bin Jardan, Musaab Dauelbait, Mohammed Bourhia

“…SHAP analysis identified key sequence motifs (e.g., "UUG") and structural free energy (ΔG = − 12.3 kcal/mol) as critical predictors, validated by PCA (82% variance) and t-SNE clustering. …”
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Decentralized fintech platforms adoption intention in cyber risk environment among GenZ: A dual-method approach using PLS-SEM and necessary condition analysis by Md Sharif Hassan, Nguyen Hong Mai, Nor Shaipah Abdul Wahab, Mohammad Bin Amin, Md Maruf Hassan, Judit Oláh

“…A total of 391 valid responses were received. The data were analyzed through partial least squares structural equation modeling (PLS-SEM) and necessary condition analysis (NCA). …”
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Comparison of Molnupiravir Exposure‐Response Relationships for Virology Response and Mechanism of Action Biomarkers With Clinical Outcomes in Treatment of COVID‐19 by Akshita Chawla, Ruthie Birger, Brian M. Maas, Youfang Cao, Hong Wan, Julie Strizki, Arthur Fridman, Amanda Paschke, Carisa deAnda, Wei Gao, Matthew L. Rizk, Wendy Painter, Wayne Holman, Susanne Sardella, George Painter, Julie A. Stone

“…E‐R relationships were best represented by an Emax structural model with reasonable consistency in the estimated AUC50s (~2.3‐fold), across the models, of 10,260 and 4390 nM*hr. for day 5 viral load change from baseline and LNS error rate, respectively. …”
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Mapping rapeseed (Brassica napus L.) aboveground biomass in different periods using optical and phenotypic metrics derived from UAV hyperspectral and RGB imagery by Chuanliang Sun, Chuanliang Sun, Weixin Zhang, Genping Zhao, Qian Wu, Wanjie Liang, Ni Ren, Hongxin Cao, Lidong Zou, Lidong Zou

“…Vegetation indices (VI), texture features (TF), and structural features (SF) were extracted from UAV hyperspectral and ultra-high-resolution RGB images to assess their correlation with rapeseed biomass at different growth stages. …”
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Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicryResearch in context by Xin Ma, Jian Zhang, Qianling Jiang, Yong-Xin Li, Guan Yang

“…Of note, half of these analogs could bind to MHC II and interact with TCR through structural modeling of the interaction using fine-tuned AlphaFold. …”
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Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure by Zhenglong Guo, Yunfei Liu, Zhiming Zhou, Jianchao Chen, Lin Guo, Keke Liang, Yibin Hao, Bingtao Hao, Bin Yang, Shixiu Liao

“…Conclusions These findings suggest that the epigenetic dysregulation of cardiac stress-response and structural genes contributes to the pathogenesis of DCM-HF. …”
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A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein by Juan José Valenzuela-Fuenzalida, Benjamín Rodríguez-Osorio, Cristian Salgado-Torres, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandro Bruna-Mejías, Roberto Avila-Sepulveda, Álvaro Becerra-Farfán, Macarena Rodríguez-Luengo, Juan Sanchis-Gimeno, Guinevere Granite, Héctor Gutiérrez-Espinoza

“…The knowledge of HPV and its anatomical variants is of utmost importance for both medical professionals and anatomists, as it is one of the vessels that collects blood from many important viscera found in the abdominal cavity, any structural alteration could be crucial in diagnosis and surgical procedures.…”
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Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project by Linda Sharp, Sarah Bailey, Colin Rees, Willie Hamilton, Dawn Craig, Joe West, David Humes, Gary Abel, James Turvill, Brian Nicholson, Chloe Thomas, Jim Chilcott, Colin Crooks, Olena Mandrik, John Whelpton

“…Cost-effectiveness improves as risk thresholds rise. High structural uncertainty around cancer progression during diagnostic delay and diagnosis of other serious bowel diseases considerably affects cost-effectiveness.Conclusions COLOFIT is likely to be more cost-effective than FIT alone and could help alleviate pressure on diagnostic services. …”
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Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California by Abtin Shafie, Alexis Salvatore, Riley Shea, Eileen Yu, Oyku Ozyucel, Ansharan Akbar, Bow Suprasert, Erin C. Wilson, Willi McFarland, Kelly D. Taylor, Sean Arayasirikul

“…OBJECTIVE: Research among transgender women has found health, but especially mental health, to be shaped by social inequities and multiple, intersectional, structural vulnerabilities. While some studies have shown that transgender adults are also more likely to have a disability than cisgender adults, few studies have explored this intersection. …”
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Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China by Hongwei Liu, Ziyao Jia, Huifang Xu, Xiaoyang Wang, Hong Wang, Ruihua Kang, Qiong Chen, Xiaoli Guo, Ranran Qie, Mengfei Zhao, Cheng Cheng, Liyang Zheng, Shuzheng Liu, Yin Liu, Shaokai Zhang, China Working Group on Colorectal Cancer Survey

“…The multivariable regressions and structural equation model (SEM) were used to assess the association between characteristics and HRQOL. …”
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Repositioning FDA-Approved Sulfonamide-Based Drugs as Potential Carbonic Anhydrase Inhibitors in <i>Trypanosoma cruzi</i>: Virtual Screening and In Vitro Studies by Eyra Ortiz-Pérez, Adriana Moreno-Rodríguez, Timoteo Delgado-Maldonado, Jessica L. Ortega-Balleza, Alonzo González-González, Alma D. Paz-González, Karina Vázquez, Guadalupe Avalos-Navarro, Simone Giovannuzzi, Claudiu T. Supuran, Gildardo Rivera

“…Future studies should focus on structural modifications to improve selectivity. Integrating docking, parasitological, and enzymatic data is crucial for optimizing drug candidates for Chagas disease.…”
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Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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