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51721
Classification and definition of epilepsy. Position paper by the International League Against Epilepsy on Nosology and Definitions of Epilepsy Syndromes dated 2021
Published 2022-06-01“…It also introduces a new etiology-defined class of epilepsy syndromes characterized by specific genetic, metabolic, and structural causes. The document does not cover therapy for epilepsy syndromes; however, for some of them, it specifies the most effective or potentially aggravating antiepileptic drugs. …”
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51722
Personality Traits and Social Support: Their Role in Postpartum Depression
Published 2025-08-01“…Analyses included descriptive statistics, correlation analysis, moderation testing with PROCESS macro (SPSS v4.2), and Structural Equation Modeling (SEM).Results: The average EPDS score was 7.9 (SD = 4.3), indicating generally low to moderate levels of PPD. …”
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51723
Neuroinflammation and Natural Antidepressants: Balancing Fire with Flora
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51724
St. Louis enhancing engagement and retention (STEER) in HIV/AIDS care: a participatory intersectional needs assessment for intervention and implementation planning
Published 2025-06-01“…Louis has a marked history of structural racism and economic inequities, we utilized the Intersectionality Based Policy Analysis (IBPA) framework to guide a participatory needs assessment for planning and program development.MethodsThe planning team included researchers, the lead implementer from our community partner, and two community representatives, and had biweekly 60–90 min meetings for 18 months. …”
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51725
The Impact of Chinese Foreign Direct Investment on US Industry
Published 2025-07-01“…Overall, FDI emerges as a potentially transformative force whose developmental impact is shaped by both firm-level strategies and broader structural conditions, offering a nuanced foundation for analyzing its empirical relationship with U.S. industry performance. …”
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51726
Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey
Published 2025-05-01“…Among the revealed abnormalities, 130 (97.7%) were structural chromosome anomalies, while only 3 (2.3%) numerical chromosome anomalies were observed, including sex chromosome aneuploidy in 2 cases and mosaic karyotype in one case. …”
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51727
Multi-level determinants of vaccination of the American Indian and Alaska Native population: a comprehensive overview
Published 2025-02-01“…Federal policies may increase IHS funding, tribal infrastructure, and AIAN data representativeness while eliminating structural racism and generational trauma.ConclusionThis article contributes to literature and practice. …”
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51728
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51729
Occurrence phase and gas-bearing evolution of deep coalbed methane
Published 2025-03-01“…The evolution pattern of deep burial and weak structural transformation intensity is conducive to the enrichment of free gas and is a favorable zone for deep coalbed methane exploration and development. …”
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51730
Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow
Published 2025-02-01“…A selected subset of the identified antigens is then expressed recombinantly to isolate antigen-specific IgG, followed by characterization of the structural and functional properties of these antibodies. …”
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51731
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51732
Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics
Published 2025-07-01“…Very little is understood about the underlying pathogenesis underpinning injury at this location, especially the contribution of keratinocytes and other structural skin cells. We performed single-cell RNA sequencing to compare the transcriptome of epidermal and dermal chronic GVHD samples with that of healthy control samples. …”
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51733
Food parenting stress among caregivers receiving government food assistance: a study from the United States
Published 2025-09-01“…Nutrition education should be paired with supports that address structural barriers.…”
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51734
ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells
Published 2025-01-01“…The induced responses obtained under time-variant ODEP stimulation reflect the cells’ chemical, morphological, and structural characteristics in an automated, flexible, and label-free manner. …”
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51735
Evaluation of dengue virus seroprevalence in four boroughs of Mexico City among persons aged 5-35 years in 2022
Published 2025-02-01“…However, it is important to note that the structural conditions of the dwellings in these boroughs, which offer minimal barriers to vector infestation, could facilitate the establishment of local transmission under favorable conditions. …”
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51736
Oral Small-Molecule GLP-1 Receptor Agonists: Mechanistic Insights and Emerging Therapeutic Strategies
Published 2025-06-01“…Nevertheless, challenges persist regarding hepatic safety, pharmacodynamic variability, and limited long-term outcome data. This review integrates current structural, pharmacological, and clinical evidence, highlights key mechanistic innovations—including biased agonism, covalent binding strategies, and allosteric modulation—and discusses future directions for this rapidly evolving therapeutic class in metabolic disease management.…”
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51737
Comprehensive Dissolution Study on Two Double Ce(IV) Phosphates with Evidence of Secondary CeO<sub>2</sub> Nanoparticle Formation
Published 2025-05-01“…In contrast, the nanophase NaCe<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub> exhibits exceptional structural and chemical stability, showing no signs of recrystallisation, phase transformation, or CeO<sub>2</sub> formation, even after extended ageing. …”
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51738
USP7 V517F mutation as a mechanism of inhibitor resistance
Published 2025-03-01“…We discovered a key treatment-emergent heterozygous mutation (V517F) in USP7 in the binding pocket of compounds as the primary cause of resistance to the USP7 inhibitor USP7-797. Our structural analysis, supported by AlphaFold2 predictions, indicates that the V517F mutation altered the conformation of the compound binding pocket, causing steric hindrance and reducing the affinity between USP7 and its inhibitors. …”
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51739
Determinants of ICT Adoption and Performance in Healthcare: The Role of Individual Attributes and Organizational Contextual Factors
Published 2025-01-01“…We conducted a global survey involving healthcare professionals (n =204) to understand the role of various determinants in adopting ICTs and their implications for organizational performance. Data was analyzed using Partial Least Squares Structural Equation Modelling (PLS-SEM) and multiple regression for micro-level constructs. …”
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51740
The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio
Published 2025-05-01“…The meprin/A5/PTPmu (MAM) domain, a conserved structural motif in transmembrane proteins, remains undercharacterized in CRC pathogenesis. …”
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