Direct lateral interbody fusion with indirect decompression of the spinal roots in patients with degenerative lumbar spinal stenosis by Ilya D. Isakov, Abdugafur J. Sanginov, Shamil A. Akhmetyanov, Evgeniy A. Mushkachev, Artem N. Sorokin, Alexey V. Peleganchuk

“…Introduction Degenerative spine conditions involve the gradual loss of normal structure of the spine among the population and remain a common form of work-limiting health condition in 80 % of the population. …”

Faster efficacy and reduced nodule occurrence with PLLA (poly-l-lactic acid) porous microspheres by Qihua Cao, Qihua Cao, Qihua Cao, Jiayu Chen, Jiayu Chen, Jiayu Chen, Jiayu Chen, Zijun Zhang, Yufei Xiong, Jinxia Ma, Wei Sun, Xin Chen, Qilei Lou, Kaijia Tang, Kaijia Tang, Kaijia Tang, Kaijia Tang, Feng Lin, Feng Lin, Feng Lin, Yueliang Zhu, Yueliang Zhu, Yueliang Zhu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu

“…Post-euthanasia, tissue sections underwent histological examination through hematoxylin and eosin (H&E) staining and Masson’s trichrome technique, with subsequent statistical analysis of the observational data.ResultsThe PLLA porous microsphere group demonstrated significantly faster onset of action compared to the control, with observable collagen deposition as early as week 2, enhanced inflammatory cell infiltration, more homogeneous tissue distribution, and substantially fewer microaggregates upon histological examination.DiscussionStructural modification of PLLA microspheres has successfully accelerated their onset of action while reducing nodule formation, thereby providing novel insights for clinical applications.…”
Get full text

An open-source simulation platform to support and foster research collaboration in natural hazards engineering by Adam Zsarnóczay, Gregory G. Deierlein, Frank McKenna, Matthew Schoettler, Sang-Ri Yi, Barbaros Cetiner, Aakash Bangalore Satish, Jinyan Zhao, Justin Bonus, Abiy F. Melaku, Sina Naeimi, Pedro Arduino, Rachel Davidson, Rachel Davidson, Catherine Gorle, Sanjay Govindjee, Ahsan Kareem, Tracy L. Kijewski-Correa, Tracy L. Kijewski-Correa, Laura N. Lowes, Michael Motley, Seymour M. J. Spence, Ertugrul Taciroglu, Alexandros A. Taflanidis, Matthew DeJong

“…This paper presents the conceptual foundation and current capabilities of the SimCenter platform, covering hazard characterization, structural response analysis, damage and loss estimation, and recovery modeling. …”
Get full text

Signatures of omicron-like adaptation in early SARS-CoV-2 variants and chronic infection by Mark Tsz Kin Cheng, Mazharul Altaf, Jesu Castin, Ann-Kathrin Reuschl, Benjamin L. Sievers, Kimia Kamelian, Dejan Mesner, Rebecca B. Morse, Adam Abdullahi, Bo Meng, Kata Csiba, Steven A. Kemp, Darren P. Martin, Clare Jolly, Christopher Ruis, Lipi Thukral, Ravindra K. Gupta

“…P812S conferred evasion of a FP-targeting monoclonal antibody, consistent with FP-region structural rearrangements. Finally, P812S-bearing viruses showed evasion of polyclonal neutralizing antibodies in sera from vaccinated individuals at 32C. …”
Get full text

Spatial Characteristics and Influencing Factors of Human Settlement Environment in the Kuye River Basin by Zhonghua ZHANG, Hao WU

“…Utilizing ArcSWAT 2012 software, hydrological simulations are conducted for the Kuye River Basin. Input data includes DEM (digital elevation model) data, soil type data, and meteorological information specific to the basin, enabling the simulation and acquisition of hydrological factors such as sub-basin boundary and river network grade. …”
Get full text

Precision Target Spraying System Integrated with Remote Deep Learning Recognition Model for Cabbage Plant Centers by ZHANG Hui, HU Jun, SHI Hang, LIU Changxi, WU Miao

“…A Ghost-Backbone lightweight network structure was introduced, integrating remote sensing technologies along with the sprayer's forward speed and the frequency of spray responses. …”
Get full text

Identification of biomarkers and potential drug targets in DFU based on fundamental experiments and multi-omics joint analysis by Xudong Xin, Xudong Xin, Xudong Xin, Xudong Xin, Haidong Zhou, Song Huang, Wenzhao Zhang, Jiahou Xu, Wei Wang, Jihua Wei, Jihua Wei, Jihua Wei, Jihua Wei, Liqing Li

“…Molecular docking studies revealed that quercetin exhibits a lower binding energy with the target protein binding site, forming a stable structure. Single-cell analysis indicated that SAMHD1 is predominantly expressed in macrophages, whereas DPYSL2 is expressed not only in macrophages but also significantly in vascular endothelial cells and other cell types. …”
Get full text

Non-specific effects of different sham acupuncture methods and their impact on true acupuncture effectiveness in migraine: a protocol for systematic review and network meta-analysi... by Fan Jiang, Haifeng Zhang, Lun Li, Qinhong Zhang, Meng Lin, Yongjian Liu, Yong Fu, Jiahui Yang, Qilin Liu, Meiyi Zhu, Xiumei Yan

“…A frequentist NMA will be executed using Stata (V.18.0). The network structure will comprise: acupuncture as a single node (or multiple nodes if heterogeneity warrants), different SA methods as separate nodes, and waiting-list/no-treatment as a single node. …”
Get full text

Pneumatic Compliant End-effector Using Multi-compensation Integrated Nonlinear Active Disturbance Rejection Control by ZHANG Shuzhong, WU Qianxin, DAI Fuquan, WANG Yabing, ZHANG Gong

“…Among various end-effector mechanisms, the pneumatic type is widely adopted due to its lightweight structure, low cost, robustness, and ease of maintenance. …”
Get full text

Etiological mechanisms underlying the hazard factors and inflammatory bowel disease: a prospective cohort study by Yi Tao, Yongjia Li, Tianyi Zhou, Lei Zhao, Pan Li, Minghong Sun, Lijuan Zhang, Lihong Yang, Ting Chen, Xuemei Lian, Xiaoni Zhong

“…Finally, we constructed a structural equation model to elucidate the complex pathogenic mechanisms and interactions among genetic risks, lifestyle factors, dietary habits, comorbidities, and immune metabolism in the progression of IBD. …”
Get full text

Facial Expression Recognition and Digital Images Infosecurity for Prevention Care System Application in Sudden Infant Death Syndrome Monitoring by Chih-Te Tsai, Chia-Hung Lin, Hsiang-Yueh Lai, Yu-En Cheng, Ping-Tzan Huang, Neng-Sheng Pai, Chien-Ming Li

“…For image infosecurity testing, the number of pixel changing rate (NPCR), unified averaged changed intensity (UACI), and structural similarity index measurement (SSIM) were employed to evaluate the performances for encryption and decryption processes, ensuring confidentiality, recoverability, and availability of transmitted images. …”
Get full text

For-profit growth and academic decline: a retrospective nationwide assessment of Brazilian medical schools by Bruno B. Andrade, Bruno B. Andrade, Klauss Villalva-Serra, Klauss Villalva-Serra, Rodrigo C. Menezes, Rodrigo C. Menezes, Luiz F. Quintanilha, Katia de Miranda Avena, Katia de Miranda Avena

“…These patterns suggest a structural misalignment between the commercial logic of expansion and the core educational mission of medical training. …”
Get full text

EFFECTS OF PROLINE-RICH PEPTIDES OF THE INNATE IMMUNE SYSTEM ON DRUG-RESISTANT BACTERIAL STRAINS by M. S. Zharkova, P. M. Kopeykin, G. E. Afinogenov, D. S. Orlov, A. Yu. Artamonov, K. E. Safiullina, M. S. Sukhareva, E. V. Tsvetkova, B. L. Milman, A. G. Afinogenova, O. V. Shamova

“…Lack of hemolytic activity towards human red blood cells is an important benefit of the studied peptides when used at concentrations several times higher than those showing antimicrobial effects. The data obtained presume certain prospects for further investigations of proline-rich peptides, as well as their structural modifications, for the development of new combined drugs based on these compounds, in order to combat antibiotic-resistant microorganisms, e.g., medications for local applications, various components of medical devices, in particular, venous catheters, stents and wound dressings.…”
Get full text

The Middle to Late Triassic of Central Saudi Arabia with emphasis on the Jilh Formation. Part I: lithostratigraphy, facies and paleoenvironments, palaeontology and biostratigraphic... by Le Nindre, Yves-Michel, Vaslet, Denis, Vrielynck, Bruno, Krystyn, Leopold, Manivit, Jacques, Memesh, Abdullah, Davies, Roger Brett

“…Part II “Sequence stratigraphy, depositional and structural evolution, and regional correlations” exploits the results of Part I, providing a dynamic reconstruction and a renewed vision of the Middle to Late Triassic at the regional scale.The Jilh Formation at outcrop consists of a multilayer system of thinly bedded, mixed siliciclastics with subordinate carbonates and evaporites, representing non-marine to offshore settings. …”
Get full text

Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…A physicochemical, structural, and molecular comparison was conducted with exosomes (EXOs) released from the same batch of cells. …”
Get full text

Metabolomic and Transcriptomic Analysis Revealed the Maturation Mechanism of White-Fleshed Strawberry by Linlin Xu, Xiaodong Chen, Qinglian Wang, Mizhen Zhao, Yushan Qiao, Zhaobiao Xie, Chuanwen Sun, Miao Sun, Weijian Cai

“…Further analysis revealed a co-expression of MYBs, bHLHs, NACs, and WRKYs with the structural genes mentioned. Overall, our findings uncovered a molecular mechanism regulating the maturation of white-fleshed strawberry, providing valuable insights for enhancing the flavor of white-fleshed strawberry through the gene-editing technique.…”
Get full text

La construction sociale de la “déscolarisation” : examen d’un dispositif départemental de signalement de l’absentéisme by Jean-Paul Géhin

“…The strenght of interpretations in terms of psychological weakness and breaking up of family structure contributes to minimise social dimensions and to underestimate the role of school itself in the process of “deschooling”.…”
Get full text

La réserve autochtone « transfrontalière » d’Akwesasne entre Canada et États-Unis, zone de contrebande et faille dans la sécurisation de la frontière by Guillaume Poiret, Pierre-Alexandre Beylier

“…New nation-wide networks operating there are creating changes in the local daily life of both the inhabitants of the reservation and those living around. Using datas collected from the police archives and interviews with local authorities, this paper aims to explain those evolutions and determine the nature and structure of the new traffics including their spatial extension, also describing the new policies implemented at the border to counter the traffics.…”
Get full text

Hypoxia-inducible factors: details create a picture. Part I. HIF-1 by G. A. Ignatenko, N. N. Bondarenko, S. V. Tumanova, T. S. Ignatenko, A. A. Kaluga, Ya. S. Valigun

“…The review presents a comparative analysis of scientific data on the structural and functional characteristics of subunits (HIF-1α and HIF-1β) of hypoxia-inducible transcription factor-1 (HIF-1). …”
Get full text

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines by Ye. O. Karpun, N. M. Polishchuk

“…The aim of this work was to develop the antimicrobial and antifungal effects of the homologous series of S-alkyl-substituted 4-R-5-(((3-(pyridin-4-yl)-1H-1,2,4-triazole-5-yl)thio)methyl)-4Н-1,2,4-triazole-3-thiols and draw conclusions regarding the structural and functional relationship of the synthesized compounds. …”
Get full text