Deep learning-based carotid plaque vulnerability classification with multicentre contrast-enhanced ultrasound video: a comparative diagnostic study by Yanli Guo, Hongxia Zhang, Yang Guang, Wen He, Bin Ning, Chen Yin, Mingchang Zhao, Fang Nie, Pintong Huang, Rui-Fang Zhang, Qiang Yong, Jianjun Yuan, Yicheng Wang, Lijun Yuan, Litao Ruan, Tengfei Yu, Haiman Song, Yukang Zhang

“…Moreover, with a more powerful network structure and better utilisation of video information, DL-DCCP provided greater diagnostic accuracy than a state-of-the-art static CNN model.Trial registration number ChiCTR1900021846,…”
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A Multifaceted Computational Approach to Identify PAD4 Inhibitors for the Treatment of Rheumatoid Arthritis (RA) by Mansour S. Alturki, Mohamed S. Gomaa, Nada Tawfeeq, Abdulaziz H. Al Khzem, Mohsina B. Shaik, Murtadha Alshaikh Jafar, Mohammad Alsamen, Hasan Al Nahab, Mohammad Al-Eid, Alhassan Almutawah, Thankhoe A. Rants’o, Khaled A. G. Ayil, Mohammed Almaghrabi

“…Methods: We utilized Maestro Schrödinger as a computational tool for preparing and docking simulations on the PAD 4 enzyme crystal structure that is retrieved from RCSB Protein Data Bank (PDB ID: 4X8G) while the docked FDA-approved medications are obtained from the Zinc 15 database. …”
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Key motor and non-motor features in early dementia with Lewy bodies by Anna Planas-Ballvé, Anna Planas-Ballvé, José Rios, Lourdes Ispierto, Mireia Gea, Laia Grau, Marta Jiménez, Cynthia Cáceres, Sílvia Martínez, Katrin Beyer, Ramiro Álvarez, Pau Pastor, Dolores Vilas, Dolores Vilas

“…Demographic and clinical data were collected, and motor and non-motor symptoms were assessed using structured interviews and validated scales and questionnaires.ResultsA total of 107 participants were included (23 DLB, 27 PD, 26 AD, and 31 controls). …”
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Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar indiv... by Heidi Ka Ying Lo, Roger S. McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys, Ka Fai Chung

“…Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect. …”
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Behavioural activation in nursing homes to treat depression (BAN-Dep): study protocol for a pragmatic randomised controlled trial by Simon Gilbody, Christopher Etherton-Beer, Kathryn A Ellis, Leon Flicker, Diana Velasquez Reyes, Hema Patel, Nicola Lautenschlager, Andrew H Ford, Eleanor Curran, Rachael Kelly, Rhoda Lai, Terence Chong, David Ekers, Dina Lo Giudice, Angelita Martini, Osvaldo P Almeida

“…Only de-identified group data will be presented.Trial registration ACTRN12618000634279.…”
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Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH) by Kristin Mayes, Victor B. Talisa, Adelina Malito, Florian B. Mayr, Kelly Williams, Kalpana Char, Richard Wadas, Elizabeth Lorenzi, Kert Viele, Rana Awdish, Derek C. Angus, Chung-Chou Ho Chang, Sachin Yende

“…Methods: Adults admitted to the hospital with sepsis or lower respiratory tract infection (index admission) are recruited and randomized to usual care (structured telephonic support [STS]) or one of four post-discharge RPM care models in addition to STS. …”
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Implementation of a Patient Navigation Program to Support Representative Participation in Cancer Clinical Trials by Sukh Makhnoon, Fabian Robles, Jessica L. Lee, D'Angelo Grant, Marisol Rojas, Ang Gao, Carla Pezzia, Venkata Eluri, Navid Sadeghi, Song Zhang, Thomas Hulsey, Rebecca Renn, Erin L. Williams, Heather Kitzman, David E. Gerber

“…Evaluation was guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework and incorporated programmatic data, structured surveys of patients and staff, and qualitative patient interviews. …”
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Application of HRCT-based radiomics to predict interstitial lung disease for juvenile dermatomyositis by Lingke Liu, Minfei Hu, Yun Zhou, Fei Zheng, Xiaohui Ma, Li Yang, Yiping Xu, Liping Teng, Bin Hu, Meiping Lu, Xuefeng Xu

“…Methods We retrospectively analyzed clinical data of 56 children with JDM, and all participants gave written informed consent. …”
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The effects of formula milk on development, nutrient absorption, and immune characteristics of piglets by Chuang Tang, Zhengjiang Liu, Lu Lu, Bo Zeng, Zhi Li, Ruohan Yang, Duoduo Zhang, Xiaolan Fan, Jiaxue Cao, Haohuan Li, Jing Sun, Jinwei Zhang, Xiaoyuan Wei, Wei Sun, Liangpeng Ge, Mingzhou Li, Fanli Kong

“…Given the ethical constraints in conducting experimental studies on human breastfeeding, we employed pig, which have similar physiological structure with humans, to examine the impacts of different feeding practices. …”
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The impact of nuchal ligament ossification resection on cervical stability after modified laminoplasty: a long-term follow-up study by Chong Chen, Wenlin Ye, Tao Yu, Xing Cheng, Lutong Wang, Xingchen Zhao, Xiang Long, Jun Ouyang, Yunbing Chang, Xiaoqing Zheng

“…For DCM patients with long segmental ONL, more attention should be paid to protecting the MLC structure during posterior cervical surgery. Clinical trial number Not applicable.…”
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Australian treatment outcome study: protocol for the 18–20-year follow-up of a prospective longitudinal cohort examining the natural history of heroin dependence and associated mor... by Maree Teesson, Paul S Haber, Christina Marel, Katherine Mills, Rachel Visontay, Jack Wilson, Shane Darke, Joanne Ross, Tim Slade, Katherine Haasnoot, Madeleine Keaveny, Chris Tremonti

“…The 18–20-year follow-up will consist of: (1) a structured interview; (2) physical health assessment; and (3) data linkage. …”
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Prevalence of tick-borne pathogens in feeding and questing Ixodes ricinus ticks from Southern Sweden by Chiara Cialini, Alessandra Cafiso, Mattias Waldeck, Åsa Lundgren, Johan Fält, Bo Settergren, Phimphanit Choklikitumnuey, Giulia Chiappa, Eleonora Rosso, Laura Roveri, Elisa Fesce, Nicola Ferrari, Per-Eric Lindgren, Chiara Bazzocchi, Giulio Grandi

“…This study highlights the presence of several zoonotic TBPs in Skåne, emphasizing the need for a structured monitoring plan and preventive strategies within a One Health framework.…”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…In this study, participants who underwent free cataract surgery between January and August 2014 received a telephone interview based on a structured questionnaire. Data were collected on patient demographics, resources, health conditions, reasons for undergoing the free surgery and overall evaluation of the free cataract surgery programme.Results Among the 833 participants, the mean surgical age was 76.85±7.46 years (95% CI 76.34 to 77.36), and the male to female ratio was 385:448. …”
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Assessing antibiotic use practices on central Burkina Faso cattle farms and the associated risks to environmental and human health contamination: A pilot study by Djifahamaï Soma, Fatimata Bintou J. Diarra, Isidore Juste O. Bonkoungou, Namwin Siourimè Somda, Evariste Bako, Marguerite Edith M. Nikiema, Souleymane Sore, Natéwindé Sawadogo, Nicolas Barro, Daouda Kassié

“…Materials and Methods: In April 2023, a survey was conducted among 50 cattle farm owners and managers across four peri-urban area of Ouagadougou, Burkina Faso. Data were collected using structured questionnaires through Kobo Toolbox. …”
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Short-term PM1 exposure and sleep duration: a nationwide study using consumer-grade wearable devices by Jiajun Liu, Mintao Su, Junxiong Ma, Qinfeng Zhou, Hanxu Shi, Yujie Shi, Shuyu Huang, Yuchuan Tang, Peining Zhou, Kunyao Yu, Rui Su, Rui Zhou, Jing Wei, Jing Ma, Zhenyu Zhang

“…Although individual sleep duration changes appear modest, the cumulative impact of PM _1 on sleep structure, especially in vulnerable populations, poses significant public health risks in physiological restoration. …”
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OptiNeoCare: optimisation of routine care in the management of severe perinatal asphyxia in full-term or near-term newborns – study protocol for analysis of suboptimal care by conf... by Pierre-Yves Ancel, Thierry Debillon, Gilles Cambonie, Geraldine Favrais, Gilles Kayem, Hendy Abdoul, Ayoub Mitha, Isabelle Guellec, Gauthier Loron, Charles Garabedian, Thomas Desplanches, Pierre Delorme, Eric Verspyck, Cyril Huissoud, Marie Delnaud, Blanche Graesslin, Pierre Tourneux, Maliha Badr, Sophie Chapeliere, Marie Brasseur-Daudruy, Max Gonzalez Estevez, Agnes Rigouzzo

“…The quality of care will be assessed based on a structured classification of medical errors (diagnostic, therapeutic, preventive and systemic) by a panel of experts including an obstetrician or midwife and a paediatrician. …”
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Effects of intermittent theta burst stimulation (iTBS) on appetite change and body weight in inpatients with schizophrenia in China: study protocol for a randomised controlled tria... by Jun Yang, Jing Huang, Jin Yang, Yue Qin, Renrong Wu, Jieyu Liu, Baoyan Xu, Haiyu Chen, Tianxiang Zou, Ziwei Teng, Tengteng Zhang, Yuhan Su, Zaiwen Dong, Chong Yang

“…MRI examination will be conducted to detect brain structure, perfusion and functional connectivity. Data analysis will be conducted in a modified intention-to-treat population. …”
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Coronary inflammation and atherosclerosis by CCTA in young adults (aged 18-45) by Annalisa Filtz, Daniel Lorenzatti, Henry A Dwaah, Carlos Espiche, Santiago F Galgani, Jake T Gilman, Alexandrina Danilov, Andrea Scotti, Piotr J Slomka, Daniel S Berman, Salim S Virani, Mario J Garcia, Khurram Nasir, Leslee J. Shaw, Ron Blankstein, Michael D Shapiro, Damini Dey, Leandro Slipczuk

“…Structured abstract: Background: Peri-coronary adipose tissue attenuation (PCAT), a marker of coronary inflammation, is linked to coronary artery disease (CAD), but data on the role of PCAT in young individuals are limited. …”
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Impact of shared decision-making in Taiwanese patients with atrial fibrillation eligible for novel oral anticoagulant therapy by Yen-Wen Wu, Tsung-Hsien Lin, Yuan-Po Yang, Wei-Tsung Wu, Chung-Ming Tu, Hung-Kain Huang, Chun-Yuan Chu, Chi-Cheng Huang, Szu-Chi Chien, Shih-Jie Jhuo, Ching-Pei Chen

“…During Stage I, part I participants (n = 124) completed a semi-structured survey (understanding evaluation sections only) before and after viewing SDM materials on stroke prevention for AF. …”
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The impact of mentoring relationships on professional identity formation in medical education: a systematic review by Lalit Kumar Radha Krishna, Nila Ravindran, Hannah Yi Fang Kwok, Xuan Yu Tan, Jasper Soh, Elizabeth Yong Mei Leong, Darius Wei Jun Wan, Tiat Yan Low, Aiden Wei-Jun Chan, Nicholas Chong Jin Lim, Yen Kit Ng, Arthena Anushka Thenpandiyan, Jun Rey Leong, Adele Yi Dawn Lim, Elaine Li Ying Quah, Leia Ning Tse, Sriram PL, Sri Priyanka Rajanala, Jun Kiat Lua, Varsha Rajalingam, Victoria Jia En Fam, Ranitha Govindasamy, Nur Amira Binte AbdulHamid, Crystal Lim, Eng Koon Ong, Shin Wei Sim, Stephen Mason, Simon Yew Kuang Ong

“…Conclusions The mentoring programme can be seen as a mentoring ecosystem, functioning as a community of practice and supporting the socialisation process within its boundaries and along the mentoring trajectory. The culture and structure of the mentoring ecosystem help inculcate the shared belief systems and programme identity. …”
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