An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. The luminescent structure of CA/EDA-CDs, featuring a π-conjugated system (aromatic C=C and graphite N) and surface chromophores (C=N/C=O) connected via C-N, C-O, and hydrogen bonds, was controllably modulated by hydroxyl radical (·OH). …”
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Orthopaedic Consultation is Associated With Fewer Patient-Perceived Barriers to Total Joint Arthroplasty by Insa Mannstadt, BS, BA, J. Alex B. Gibbons, BA, Troy B. Amen, MD, MBA, Mangala Rajan, PhD, Sarah R. Young, PhD, Henry Tischler, MD, Michael L. Parks, MD, Mark Figgie, MD, Anne Bass, MD, Linda Russell, MD, Bella Mehta, MD, MS, Iris Navarro-Millán, MD, Susan M. Goodman, MD

“…Methods: We performed a post-hoc analysis of questionnaire responses based on data from a previous study that used semi-structured interviews with patients with advanced osteoarthritis. …”
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ASSESSMENT OF THE PSYCHOLOGICAL STATUS OF PATIENTS WITH GYNECOLOGICAL CANCER IN THE PROCESS OF PSYCHOLOGICAL REHABILITATION by E. V. Pestereva, V. A. Chulkova, T. Y. Semiglazova, E. G. Ulrich, O. A. Pestereva

“…Disturbing component in patients at the stage of «before operation» and dysphoric component in patients at the stage of «after surgery» were dominated on the background of ergopathic reactions to the disease in the structure of attitude to the disease. The high intensity of complaints of female patients about their health, including non-specific, indicating the psychosomatic component of the patient’s suffering was revealed. …”
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Inaccuracies of venous thromboembolism risk assessment and prevention practices among medically ill patients by Brandyn D. Lau, Aditya Bhave, Jennifer C. Yui, Rakhi Naik, Kathryn E. Dane, John Lindsley, Dauryne L. Shaffer, Peggy S. Kraus, Erik H. Hoyer, Elliott R. Haut, Michael B. Streiff

“…Leveraging existing structured data to autopopulate VTE risk assessments can assist providers in improving accuracy. …”
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Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific <i>Adar1</i> Knockout Mice by Lisa Zerad, Nadjet Gacem, Fanny Gayda, Lucie Day, Ketty Sinigaglia, Laurence Richard, Melanie Parisot, Nicolas Cagnard, Stephane Mathis, Christine Bole-Feysot, Mary A. O’Connell, Veronique Pingault, Emilie Dambroise, Liam P. Keegan, Jean Michel Vallat, Nadege Bondurand

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A preliminary study of the pathological characteristics of the internal orifice and the local mucosal microbial community in complex anal fistula by Zhu Jingyi, Zhang Ling, He Li, Zhang Jun, Mei Zubing, Wang Zhenyi, Chen Qiyi, Wang Qingming

“…[Objectives] To observe the histological morphology and Mucoprotein 2 (MUC2) expression in the internal orifice of complex anal fistula, as well as to compare the difference of the composition and structure of the microbial community in the mucosal tissue of the internal orifice of patients with complex anal fistula with the anal sinus mucosa of the healthy population. …”
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Humic acid from leonardite for cadmium adsorption and potential applications by MENG Fande, YUAN Guodong, WEI Jing, BI Dongxue, WANG Hailong, LIU Xingyuan

“…In contrast, Leo-HA is beneficial to soil structure and soil quality, as well as safe to handle in the field. …”
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PSYCHOLOGICAL FACTORS OF THE FORMATION OF LEGAL AWARENESS OF STUDENTS OF HISTORICAL AND MEDICAL EDUCATION PROFILES by Dribas Svetlana, Semenov Konstantin

“…The purpose of the article is to determine psychological factors and compare the predictor structure of legal awareness among students of historical and medical education profiles. …”
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SERIES IN SEARCH OF INTERACTIVITY / ИНТЕРАКТИВНЫЕ СЕРИАЛЫ: В ПОИСКАХ ОБРАТНОЙ СВЯЗИ by SMOLEV DANIIL D. / СМОЛЕВ Д.Д.

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Development, Validation and Approbation Analytical Method for the Quantitative Determination of Taurine by HPLC-UV Method in the Test of Comparative Dissolution Kinetics by A. M. Poluyanov, A. Kochug, L. S. Mitrofanova, I. D. Nikitin, O. Yu. Vergasov, I. E. Shohin, E. N. Fisher

“…To solve this problem, one can apply the method of pre-column derivatization, because of which an fragment is introduced into the structure, providing a bathochromic shift in the UV spectrum of the starting compound.Aim. …”
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Cell-derived exosome therapy for diabetic peripheral neuropathy: a preclinical animal studies systematic review and meta-analysis by Xianying Lu, Ran Xu, Xiaohui Dong, Dingxi Bai, Wenting Ji, Xinyu Chen, Huan Chen, Chaoming Hou, Jing Gao

“…The outcome indicators consisted of at least one of the three key DPN endpoints (electrophysiology, behavioural assessment, and nerve structure) based on the Neurodiab guidelines. R 4.4.2 software was used to conduct all statistical analyses. …”
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Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice by Li Kong, Xinyu Gao, Lijuan Zhu, Xing Lin, You Huang, Chunlin Huang, Wenjiang Yang, Yazhi Chen, Haoqiang Zhao, Jing Wu, Zhihang Yuan, Jin’e Yi

“…Betulinic acid (BA) is a natural pentacyclic lupane-structure triterpenoid that has diverse pharmacological activities. …”
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The death of a neurotrauma trial lessons learned from the prematurely halted randomized evaluation of surgery in elderly with traumatic acute subdural hematoma (RESET-ASDH) trial by R.D. Singh, J.T.J.M. van Dijck, T.A. van Essen, H.P. Nix, R.J.G. Vreeburg, H.F. den Boogert, G.C.W. de Ruiter, B. Depreitere, W.C. Peul

“…Furthermore, non-structured interviews with involved clinical research personnel were conducted. …”
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Is malathion oncogenic for mosquitoes? A transcriptomic and histological study of adults derived from malathion exposed larvae by Audrey Arnal, Erika Burioli, Lisa Jacquin, Sophie Labrut, Stéphane Duchon, Marie Rossignol, Delphine Nicolas, Beata Ujvari, Antoine Dujon, Jordan Meliani, Jérôme Abadie, Frédéric Thomas, Vincent Corbel

“…Here, we quantitatively investigated whether larval exposure to environmentally realistic concentrations of malathion could affect mosquito tissue structure and gene expression profiles of adult Aedes aegypti (yellow fever mosquitoes), using both RNA-seq and histological approaches. …”
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Retention of medical officers in the district health services of the Western Cape, South Africa: An exploratory descriptive qualitative study by Robert J. Mash, Werner Viljoen, Steve Swartz, Mumtaz Abbas, Leigh Wagner, Herma Steyn, Gavin Hendricks, Dusica Stapar, Andrew Williams, Adeloye Adeniji, Johan Schoevers, Paul Kapp

“…Medical officers were purposefully selected in terms of districts, facility types, gender, seniority and perceived likelihood of leaving in the next four years. Semi-structured interviews were performed by family physicians, and the qualitative data were analysed using the framework method. …”
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Impact of young people’s admissions to adult mental health wards in England: national qualitative study by Anne-Marie Burn, Josephine Holland, James Roe, Elinor Hopkin, Lorna Wild, Michelle Fisher, Tamsin Ford, Saeed Nazir, Bernadka Dubicka, Anthony James, Helena Tuomainen, Nicole Fung, Adam Wagner, Richard Morriss, Kapil Sayal

“…Aims To explore the impact of young people’s admissions to adult wards, from the perspectives of young people, parents/carers and mental health professionals working in adult services. Method Semi-structured interviews were conducted with 29 participants to explore experiences of receiving and delivering care in adult mental health wards. …”
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The interaction of UBR4, LRP1, and OPHN1 in refractory epilepsy: Drosophila model to investigate the oligogenic effect on epilepsy by Rui-Na Huang, Si-Yuan Luo, Tao Huang, Xiong-Sheng Li, Fan-Chao Zhou, Wei-Hao Yin, Ze-Ru Chen, Shi-Zhan Yuan, Ling-Ying Li, Bin Tang, Jing-Da Qiao

“…This study established a novel framework to clarify the multiple genetic structure of epileptogenicity in refractory epilepsy with oligogenic background, which could be critical to translational medicine and precision therapy development.…”
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Protocol for PD SENSORS: Parkinson’s Disease Symptom Evaluation in a Naturalistic Setting producing Outcome measuRes using SPHERE technology. An observational feasibility study of... by Catherine Morgan, Walter Maetzler, Oliver Watson, Lynn Rochester, Ian Craddock, Helen Matthews, Emma L Tonkin, Kirsi M Kinnunen, Roisin McNaney, Sam Whitehouse, Majid Mirmehdi, Farnoosh Heidarivincheh, Ryan McConville, Julia Carey, Michal Rolinski, Rachel Eardley, Alan L Whone

“…Acceptability of the technology will be evaluated qualitatively using semi-structured interviews.Ethics and dissemination Ethical approval has been given to commence this study; the results will be disseminated as widely as appropriate.…”
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Jet-fuel range hydrocarbon production from Reutealis trisperma oil over Al-MCM-41 derived from Indonesian Kaolin with different Si/Al ratio by Reva Edra Nugraha, Didik Prasetyoko, Nabila Argya Nareswari, Abdul Aziz, Holilah Holilah, Hasliza Bahruji, Muhammad Rahimi Yusop, Nurul Asikin-Mijan, Suprapto Suprapto, Yun Hin Taufiq-Yap, Aishah Abdul Jalil, Santi Wulan Purnami, Hartati Hartati

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Developing a national clinical competency committee for family medicine training, South Africa by Louis S. Jenkins, Mergan Naidoo, Kefilwe Hlabyago, Dirk T. Hagemeister, Neetha Erumeda, Busisiwe Cawe, Tasleem Ras, Mulimisi Ramavhuya, Owen Eales

“…These EPAs provide a structured approach to assessing and developing the competencies required for independent practice in family medicine. …”
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