Epigenetic modifications in the murine liver upon depletion of transcriptional coregulator host cell factor 1 by Shruti Kaushal, Debashruti Bhattacharya, Saran Kumar, Winship Herr, Jaspreet Kaur Dhanjal, Shilpi Minocha

“…ChIP-seq data showed altered H3K4me3 patterns at promoter and enhancer regions of key hepatic genes. …”
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Endoscopic retrograde cholangiopancreatography consultation after digestive tract reconstruction and risk factors for complications by Yan Cheng, Jiahui Feng, Xiaojia Chen, Jun Lin, Hongling Wang

“…Abstract Background Endoscopic retrograde cholangiopancreatography (ERCP) has been widely used in the diagnosis and treatment of biliary and pancreatic diseases, and its success rate and therapeutic effect are considerable, and its use in patients with gastrointestinal tract reconstruction is also increasing. The anatomical structure of the digestive tract has been changed in these patients, which makes the use of endoscopic retrograde cholangiopancreatography technically more challenging. …”
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‘That’s why I wanted him to go on dialysis’ – a qualitative inductive thematic analysis of older patients’ and their family members’ perspectives on kidney failure treatment decisi... by Robert A. Kimmitt, Charlotte M. Snead, Leila Rooshenas, Fergus J. Caskey, Joanna Coast, Rachael L. Morton, Peter Quartermaine, Luisa Quartermaine, Lucy E. Selman, Barnaby Hole

“…Family members are known to be important in these decisions. Nonetheless, data exploring family member perspectives are limited. …”
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Spatio-temporal Evolution of Land Surface Temperature and Its Response to LULC in the Urban Agglomeration of Central Yunnan by LIN Zhiqiang, PENG Shuangyun, SHI Shuangfu, HUANG Bangmei, MA Dongling, ZHU Ziyi, MA Xiaoliang, GONG Luping

“…[Conclusion] LULC is an important factor affecting the LST, and reasonable configuration of LULC structure can improve the thermal environment of urban agglomeration. …”
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Disclosure of oral pre-exposure prophylaxis use for HIV prevention among women enrolled in a contraceptive study: qualitative findings from Durban, South Africa by Ivana Beesham, Mags Beksinska, Cecilia Milford, Cecilia Milford, Leila E. Mansoor

“…Here, we describe disclosure of PrEP use among young women enrolled in a contraceptive study.MethodsIn this qualitative study, we conducted semi-structured, in-depth, face-to-face interviews with 13 women aged 18–25 years who initiated oral PrEP for HIV prevention during the Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial. …”
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Prevalence and characteristics of tobacco use among adults in Kazakhstan: A cross-sectional National Survey by Anel Ibrayeva, Marat Shoranov, Rassulbek Aipov, Adil Katarbayev, Shynar Tanabayeva, Ildar Fakhradiyev

“…A total of 6720 adults aged 18–69 years participated, selected using a weighted multistage cluster sampling method. Data were collected through structured interviews based on the WHO STEPwise approach. …”
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Color matching and translucency of single-shade resin composites: effects of restoration thickness, background shade, and aging by Hamideh Sadat Mohammadipour, Soroush Sarafraz Yazdi, Mohammad Javad Moghaddas Mashhad, Saber Babazadeh, Arsalan Shahri

“…Abstract Background Achieving a seamless color match in resin composite restorations remains a significant clinical challenge due to variations in tooth structure and background shades. The aim of this in vitro study was to assess the effect of background shade, thermal aging, and composite thickness on color matching and translucency of three single-shade resin composites. …”
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Risky sexual behaviours: Predictors and perceived effect on the health of undergraduate students in a tertiary institution in Delta State, Nigeria by Browne Okonkwo, Richard Akinola Aduloju, Christabel Nneka Ogbolu, Justice Iyawa, Otovwe Agofure, Loveth Onuwa Okololise

“…Methods: 367 undergraduate students participated in a cross-sectional survey. A structured questionnaire was used to gather data on sociodemographic traits, hazardous sexual activity categories, perceived health risks, and contributing variables. …”
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Rare but elevated incidence of hematological malignancy after clozapine use in schizophrenia: A population cohort study. by Yuqi Hu, Le Gao, Lingyue Zhou, Wenlong Liu, Cuiling Wei, Boyan Liu, Qi Sun, Wenxin Tian, Rachel Yui Ki Chu, Song Song, Franco Wing Tak Cheng, Joe Kwun Nam Chan, Amy Pui Pui Ng, Heidi Ka Ying Lo, Krystal Chi Kei Lee, Wing Chung Chang, William Chi Wai Wong, Esther Wai Yin Chan, Ian Chi Kei Wong, Yi Chai, Francisco Tsz Tsun Lai

“…<h4>Methods and findings</h4>We extracted data from a territory-wide public healthcare database from January 2001 to August 2022 in Hong Kong to conduct a retrospective cohort study of anonymized patients aged 18+ years with a diagnosis of schizophrenia who used clozapine or olanzapine (drug comparator with highly similar chemical structure and pharmacological mechanisms) for 90+ days, with at least 2 prior other antipsychotic use records within both groups. …”
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A Cross-Sectional Analysis of Oil Pulling on YouTube Shorts by Jun Yaung, Sun Ha Park, Shahed Al Khalifah

“…A total of 47 Shorts met the inclusion criteria. Data were extracted using a structured coding framework that recorded speaker type (e.g., dentist, hygienist, influencer), engagement metrics, stated benefits, oil type and regimen, the use of disclaimers or citations, and stance toward oil pulling rated on a 5-point Likert scale. …”
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The Effectiveness of Couple Therapy Based on Acceptance and Commitment ACT on Marital Violence and Desire for Separation in Couples Applying for Divorce by M Sadeghi, H Bagholi, R Azarmidakht, H Javidi

“…Methods: The present study applied a quasi-experimental, semi-experimental design with a pre-test and post-test structure, including a control group. The statistical sample consisted of 40 individuals selected from all couples seeking divorce in Yasuj, Iran, who were referred to family counseling centers in the first three months of 2023. …”
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Cloning and Analysis of the Expansin Gene BdEXP1 from Migration Plant parasitic Nematode (Bursaphelenchus doui) by Kaiyang GUO, Shifeng LIN, Rengang WANG, Li LI, Jie ZHANG, Shizhou YU, Zili WANG, Guoqin LIU

“…The BdEXP1 protein had the highest sequence similarity (64%) with the homologous protein of B. xylophilus, and contained a typical DPBB_SPI-like conservative domain and a signal peptide but no transmembrane structure, indicating that it was a secretory protein. …”
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Growth Monitoring and Promotion Service Utilization and Associated Factors Among Mothers/Caregivers of Children 0–23 Months in Sude District, Southeast Ethiopia by Birbirsa Sheri Edae, Tamiru Yazew, Hiwot Dejene Disasa, Chala G. Kuyu

“…The study included 874 participants selected through systematic random sampling. Data collected through a structured questionnaire revealed a GMP service utilization rate of 40.2%. …”
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Strategic vegetable crop distribution in Himachal Pradesh for sustainable economic and environmental outcomes by Nikhil Chandel, S. A. Wani, Mushtaq A. Lone, Ohud A. Alqasem, Aafaq A. Rather, S. A. Mir, Danish Qayoom, M. Nagy, Getachew Tekle Mekiso, Oluwafemi Samson Balogun

“…This study examined resource use efficiency in Himachal Pradesh, focusing on optimizing land allocation using Multi-Objective Programming (MOP) to maximize income and employment while minimizing fertilizer and pesticide use. Primary data were gathered from Solan and Sirmaur districts through structured questionnaires employing a multi-stage sampling design. …”
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Perception of medical and nursing students towards interprofessional nurse-physician collaboration at Al-Azhar University: a comparative cross-sectional study by Doaa Sadek Ahmed, Rania Hassan Hassan, Doaa Ali Soliman Ali, Safa Hamdy Alkalash, Abeer A. Almowafy, Samar Samy Ismail

“…Conclusion Nursing students had a more positive attitude toward nurse-physician collaboration than medical students; their perceptions were shaped by clinical training, while social media impacted medical students. Enhancing structured teamwork in training and addressing social media roles can improve collaboration and patient care.…”
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Comparative analysis of emergency medical systems in the UK and Japan: recommendations for Japan based on on-site observations in the UK by Kazuhiko Omori, Paul Vulliamy, Chris Aylwin, Hiroki Nagasawa, Shigenori Kan, Jiro Takahashi, Noriaki Yamada, Ross Davenport

“…Five Japanese emergency physicians with expertise in trauma care, ICU management, simulation-based training, and prehospital emergency services participated. Data collection included direct clinical observations, structured discussions with UK clinicians and administrators, and a review of institutional guidelines. …”
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Patient safety culture and satisfaction in Ghana: a facility-based cross-sectional study by Emmanuel Kumah, Prince Owusu Adoma, Francis Acquah, Charles Owusu-Aduomi Botchwey, Agartha Afful Boateng, Patricia Ofori Ahimah, Dorothy Serwaa Boakye, Ebenezer Addae Boahen, Vivian Kruh, Joseph Bob Kow Koomson

“…These risks or harm is linked with numerous adverse patient outcomes such as medication error, infections, unsafe surgery and diagnosis error.Objectives The general objective of this study was to investigate into the impact of patient safety culture practices experienced on patient satisfaction among patients who attend the Kwesimintsim Government Hospital in the Takoradi municipality.Methods This study was a descriptive cross-sectional study and a consecutive sampling technique was used to select 336 respondents for the study. Data was collected using a structured questionnaire and processed using Statistical Package for Social Sciences, V.21. …”
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Community-based health insurance dropout and its determinants among women in Sidama National Regional State, Southern Ethiopia, 2024: A multilevel analysis. by Kare Chawicha Debessa, Keneni Gutema Negeri, Mesay Hailu Dangisso

“…Participants were selected via a multistage sampling technique. Data were collected through structured, pre-tested face-to-face interviews encompassing demographic, household, and scheme-related factors. …”
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Gains and pains: a qualitative study on the implications of value-based health care for professionals by Veerle van Engen, Igna Bonfrer, Fabio Mieris, Malou Ensink, Anne Stiggelbout, Kees Ahaus, Martina Buljac-Samardzic

“…Interview questions and data analysis were guided by the Job Demands–Resources model. …”
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Lipitension and cardiometabolic risk factors in young people by A. V. Sineglazova, A. Sh. Fakhrutdinova, T. Yu. Kim, S. D. Parve

“…In patients with lipitension, 43,8% were diagnosed with HTN, while the remaining 56,2% had BP ≥130/85 mm Hg. In the structure of dyslipidemia in lipitension, 79,2% had abnormalities in ≥2 lipid parameters, of which increased levels of low-density lipoprotein cholesterol (LDL-C) and hypercholesterolemia (78,3%) were most often detected. …”
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