How the Functional Constitution of Plant Communities in Field Margins Affects Wild Bee Community Composition and Functional Structure by Jane Morrison, Jordi Izquierdo, Eva Hernández Plaza, José L. González-Andújar

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Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metall... by Cynthia E. Wilkins-Port, Stephen P. Higgins, Craig E. Higgins, Issey Kobori-Hotchkiss, Paul J. Higgins

“…These include members of the serine protease and MMP families that functionally constitute a complex system of interacting protease cascades and titrated by their respective inhibitors. …”
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The Role of Post-Translational Modifications in Necroptosis by Hao Xiao, Zeping Han, Min Xu, Xukang Gao, Shuangjian Qiu, Ning Ren, Yong Yi, Chenhao Zhou

“…Post-translational modifications (PTMs)—chemical alterations occurring after protein synthesis that critically regulate protein functionality—constitute essential regulatory components within these complex signaling cascades. …”
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Network flow optimization for restoration of images by Boris A. Zalesky

“…We also consider the problem of integer minimization of two functions, U1(x)=λ∑i|yi−xi|+∑i,j  βi,j|xi−xj| and U2(x)=∑i λi (yi−xi)2+∑i,j  βi,j (xi−xj)2, with parameters λ,λi,βi,j>0 and vectors x=(x1,…,xn), y=(y1,…,yn)∈{0,…,L−1}n. Those functions constitute the energy ones for the Ising model of color and gray-scale images. …”
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RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation by Chiu-Lun Shen, Yu-Young Tsai, Shen-Ju Chou, Yao-Ming Chang, Woan-Yuh Tarn

“…Abstract Brain-derived neurotrophic factor (BDNF) plays important roles in brain development and neural function. Constitutive knockout of the splicing regulator RBM4 reduces BDNF expression in the developing brain and causes cerebellar hypoplasia, an autism-like feature. …”
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STATUS AND PROBLEMS OF DEVELOPMENT OF CONSTITUTIONAL SCIENCE IN UKRAINE by V.M. Kampo

“…In essence, it is an encyclopedic science that covers a wide range of knowledge about the constitution, its legal, economic, ideological and other functions. Constitutional science differs from the science of constitutional law, although it is organically linked with the common object of research - the constitution and its significance in the legal maintenance of the functioning of the state and society. …”
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National occupational safety and health systems: Exploring the underlying networks for future sustainable development by Gaia Vitrano, Guido J.L. Micheli

“…As a result, a range of fundamental functions and recurring bodies, covering – to different extents – the previously identified functions, constitute the framework, which are the most transversal functions for the selected countries. …”
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Formation of a dynamic knowledge base of fuzzy inference systems for estimating changing in time objects by A. Kostikova, N. Skiter

“…In the same way as the dynamic membership function constitutes a fuzzy surface in “the degree of membership-parameter-time space”, a linguistic variable composed of dynamic terms, represents a graphically broken surface with n - vertices according to the number of terms.…”
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A framework to assess compliance training effectiveness: The case of banks in South Africa by Marié D. Botha, Stephanus P. Van der Merwe

“…Orientation: Compliance functions constitute a major cost factor for banks, with challenges in demonstrating training effectiveness. …”
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Engineered transcription-associated Cas9 targeting in eukaryotic cells by Gregory W. Goldberg, Manjunatha Kogenaru, Sarah Keegan, Max A. B. Haase, Larisa Kagermazova, Mauricio A. Arias, Kenenna Onyebeke, Samantha Adams, Daniel K. Beyer, David Fenyö, Marcus B. Noyes, Jef D. Boeke

“…Both interactions are nucleic acid sequence specific but function constitutively; thus, they provide intrinsic spatial control over DNA targeting activities but naturally lack temporal control. …”
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Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis. by Nicola Horstmann, Miguel Saldaña, Pranoti Sahasrabhojane, Hui Yao, Xiaoping Su, Erika Thompson, Antonius Koller, Samuel A Shelburne

“…Similarly, isoallelic GAS strains that were either unable to be phosphorylated at D53 (CovR-D53A) or had functional constitutive phosphorylation at T65 (CovR-T65E) had essentially an identical gene repression profile to each other and to a CovR-inactivated strain. …”
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The mechanosensitive adhesion G protein-coupled receptor 133 (GPR133/ADGRD1) enhances bone formation by Juliane Lehmann, Hui Lin, Zihao Zhang, Maren Wiermann, Albert M. Ricken, Franziska Brinkmann, Jana Brendler, Christian Ullmann, Luisa Bayer, Sandra Berndt, Anja Penk, Nadine Winkler, Franz Wolfgang Hirsch, Thomas Fuhs, Josef Käs, Peng Xiao, Torsten Schöneberg, Martina Rauner, Jin-Peng Sun, Ines Liebscher

“…In this study, we explore the impact of GPR133/ADGRD1 on osteoblast differentiation and function. Constitutive and osteoblast-specific knockouts of Gpr133/Adgrd1 in mice lead to reduced cortical bone mass and trabecularization in the femurs and vertebrae — features characteristic of osteoporosis. …”
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Antithrombotic Therapy in Patients with Malignant Lymphoproliferative Disorders Treated with Ibrutinib by EI Emelina, GE Gendlin, IG Nikitin

“…The use of ibrutinib influencing the platelet function constitutes an additional bleeding risk. A crucial task consists in risk minimization of both hemorrhagic complications and thrombosis while sticking to ibrutinib treatment. …”
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Nuclear VPS35 attenuates NHEJ repair by sequestering Ku protein by Luping Zhang, Yonghong Nie, Tuo Tang, Yanji Lu, Wenlong Li, Xian Hong, Qiang Li, Aixue Zheng, Yongpei Li, Jianwen Zhou, Li Fan, Tao Wang, Zhihui Deng

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Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis by Tomoya Kujirai, Junko Kato, Kyoka Yamamoto, Seiya Hirai, Takeru Fujii, Kazumitsu Maehara, Akihito Harada, Lumi Negishi, Mitsuo Ogasawara, Yuki Yamaguchi, Yasuyuki Ohkawa, Yoshimasa Takizawa, Hitoshi Kurumizaka

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Distinct composition of different types of Abeta plaques in the pathogenesis of Alzheimer’s disease and the role of neutrophil-derived myeloperoxidase by Jianru Sun, Xiangqi Shao, Xue Wang, Xiang-sha Yin, Wenying Qiu, Xiaojing Qian, Fan Liu, Yongmei Chen, Chao Ma

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Dicarboxylate recognition based on ultracycle hosts through cooperative hydrogen bonding and anion–π interactions by Wen-Hui Mi, Teng-Yu Huang, Xu-Dong Wang, Yu-Fei Ao, Qi-Qiang Wang, De-Xian Wang

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Landscape planning and polycentricity: potentialities for regional integration in transboundary natural resources by Franklin Gabriel Menezes Gaspar, Cecília Alexandra Abreu Coelho da Rocha, Fernando Manuel Brandão Alves

“…Complementarily, potential landscape planning strategies that can be applied to strengthen regional identity between centralities, as well as to strengthen the functional, institutional and cultural identity and integration of a polycentric region, are also presented. …”
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Natural Geography, Socioeconomic Inequalities, Institutions, and How They Affect Global Homicide Rates by Evangelos Rasvanis

“…In addition, the findings reveal that countries with higher economic status, better education and well-functioning institutions tend to exhibit lower homicide rates. …”
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Circularly polarized luminescence with high dissymmetry factors for achiral organic molecules in solutions by Ming-Jun Ji, Wen-Long Zhao, Meng Li, Chuan-Feng Chen

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