Tecovirimat in the management of poxviruses: a narrative review of available evidence by Olalekan John Okesanya, Jerico Bautista Ogaya, Ikponmwosa Jude Ogieuhi, Mohamed Mustaf Ahmed, Bonaventure Michael Ukoaka, Ojoisimi Franca Jamgbadi, Deborah Oluwaseun Shomuyiwa, Don Lucero-Prisno Eliseo, Blessing Olawunmi Amisu, Olakulehin Adebusuyi, William K. Chung, Emery Manirambona, Nimat Bola Idris, Janet Alexis A. De los Santos

“…Early intervention slowed disease progression in vulnerable populations, such as people living with HIV (PLWHIV). Recovery times, virus eradication, and symptom relief varied among studies, but wider access and usage showed better clinical symptoms and tolerable side effects. …”
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Indoor and Outdoor Exposure to PM2.5 during COVID-19 Lockdown in Suburban Malaysia by Eliani Ezani, Peter Brimblecombe, Zulfa Hanan Asha’ari, Amirul Aiman Fazil, Sharifah Norkhadijah Syed Ismail, Zamzam Tuah Ahmad Ramly, Md Firoz Khan

“…Abstract During the COVID-19 pandemic, key policies aimed at reducing exposure to the virus from social distancing, restrictions on travel through to strongly enforced lockdowns. …”
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Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C by V. T. Ivashkin, M. V. Mayevskaya, P. O. Bogomolov, I. G. Nikitin, A. O. Buyeverov, A. V. Lapshin

“…The patient of the group B received no phosphogliv treatment, they received only standard AVT according to revealed virus genotype.Results. Intravenous injection of phosphogliv, prior to beginning of standard AVT, resulted in essential decrease of serum transaminase activity in group A, that was statistically significantly different from initial level. …”
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Analysis of Air Quality Changes and Influencing Factors in Changchun during the COVID-19 Pandemic in 2020 by Hanbo Gao, Ju Wang, Tongnan Li, Chunsheng Fang

“…Abstract To study the air quality changes during the Corona Virus Disease 2019 (COVID-19) lockdown in Changchun, we analyzed the changes in pollution of six major pollutants (PM2.5, PM10, SO2, NO2, O3, CO) and correlated them with meteorological parameters, using meteorological data and pollutants concentration data. …”
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NS5A replication complex inhibitor daclatasvir in the basis of chronic hepatitis C interferon-free therapy by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

“…Daclatasvir is NS5A inhibitor which has proven high antiviral activity in relation to all hepatitis C virus genotypes. Prescription of the drug in combination to pegilated interferon and ribavirin for treatment-naive patients made possible to reduce treatment duration from 48 to 24 weeks and to increase frequency of sustained virologic response (SVR) to 87% in 1b genotypeand to 100% — in 4-th genotype. …”
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Systematic review of surface disinfection: Spraying versus wiping for COVID-19 prevention by Babasola 0. Okusanya, Muzzammil Gadanya, Anthony Nlemadim, Victoria Adaramoye, David O. Akeju, John Ehiri, Martin M. Meremiku

“…No viruses were detected on any surface after wiping with 1000 ppm of bleach for 5 min. …”
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Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) by Jean Joury, Nawal Al Kaabi, Sara Al Dallal, Bassam Mahboub, Mostafa Zayed, Mohamed Abdelaziz, Jennifer Onwumeh-Okwundu, Mark A. Fletcher, Subramanyam Kumaresan, Badarinath C. Ramachandrachar, Mohamed Farghaly

“…**Background:** Infections attributable to respiratory syncytial virus (RSV) are a major cause of hospitalization among young children worldwide. …”
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Resilience in the time of crisis: A review of the maternal, perinatal and reproductive health effects of COVID-19 in South Africa by S Fawcus, S Gebhardt, R Niit, R Pattinson

“…COVID‐19 caused a marked increase in maternal death and stillbirth rates in 2020 and 2021 due to both direct effects of the virus and indirect effects on functioning of the health system. …”
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Mortality Prediction in the Emergency Service Intensive Care Patients with Possible COVID-19: A Retrospective Cross-Sectional Study by Mehmed Ulu, M. Kaya, Y. Tunc, H. Yildirim, A. Halici, A. Coskun

“… INTRODUCTION: Despite the declining clinical importance of Coronavirus Disease 2019 (COVID-19), the virus is still causes mortality in the critically ill patients. …”
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Mortality trends during the first three waves of the COVID-19 pandemic at an urban district hospital in South Africa: A retrospective comparative analysis by O Hirachund, C Pennefather, M Naidoo

“…Severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) is the virus responsible for the COVID‐19 (C19) pandemic. …”
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COVID-19 in patients with severe mental illness: An analysis of in-patients at a psychiatric hospital in Cape Town by Haseena B. Sablay, Qhama Z. Cossie, Deirdre I. Pieterse

“…Reported comorbidities included nicotine use (71%, n = 181), hypertension (11%, n = 28) and human immunodeficiency virus (7%, n = 18). Most patients (62%, n = 156) were symptomatic for COVID-19. …”
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Adoption of Electronic Records Management System in Managing Patients Records at Kabale Regional Referral Hospital. by Musiimenta, Lucky

“…Participants gave the challenges as low service quality due to lack of qualified staff, followed by inadequate knowledge, Lack of security and privacy, technological changes, unstable power supply, additional operating costs, computer viruses, and lastly information hacking and misuse Possible ways of improving electronic records in Kabale Regional Referral Hospital were installation of anti virus soft wares which was ranked highly by the Participants followed by regular change of passwords, using only trained personnel, Restrictions on access to records, have stable power supply, Records be maintained in its Cycle, have a backup system and more workshops be provided to all records keepers at Kabale RRH for proper maintenance of records. then finally the study recommended that there is need for the hospital to increase its training programs or workshops in electronic records keeping to the record managers, recruit trained personnel and the records and information keeping department should keep viruses monitoring soft ware's updated…”
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Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

“…A recent epidemiological study in China showed that local beekeepers have a level of immunity against SARS-CoV-2 with and without previous exposure to virus. BV anti-inflammatory properties are associated with melittin and phospholipase A2 (PLA2), both of which show activity against enveloped and non-enveloped viruses, including H1N1 and HIV, with activity mediated through antagonist activity against interleukin-6 (IL-6), IL-8, interferon-g (IFN-g), and tumor necrosis factor-a (TNF-a). …”
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Community Drivers Affecting Adherence to WHO Guidelines Against COVID-19 Amongst Rural Ugandan Market Vendors. by Usman, Ibe Michael, Ssempijja, Fred, Ssebuufu, Robinson, Lemuel, Ann Monima, Archibong, Victor Bassey, Ayikobua, Emmanuel Tiyo, Aruwa, Joshua Ojodale, Kembabazi, Stellamaris, Kegoye, Eric Simidi, Ayuba, John Tabakwot, Okeniran, Olatayo Segun, Echoru, Isaac, Adeoye, Azeez, Mujinya, Regan, Nankya, Viola, Keneth Iceland, Kasozi

“…To successfully contain the spread of the virus, special attention needs to be given to this set of people by assessing the type of information, source of information, and practices they inculcate as regards adherence to WHO guidelines in the fight against COVID-19 in Uganda. …”
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Characterization and genomic analysis of a Herelleviridae bacteriophage UHP46 infecting mastitis-causing Staphylococcus aureus by Sara Najeeb, Imran Khan, Javed Muhammad, Muhammad Jahangir, Iqbal Ahmad Alvi, Anza Abbas, Aman Ullah, Arif Ullah, Wajiha Sajjad, Hashir Khan, Amjad Khan, Amjad Khan

“…Genomic analysis revealed that phage UHP46 is a dsDNA virus with an approximate genome size of 139,731 bp, and it encodes 72 proteins with known functions and 136 hypothetical proteins. …”
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Efficacy and safety of the first domestic pegilated interferon alpha-2b «Pegaltevir» at chronic hepatitis C: pilot data of phase III clinical study by V. T. Ivashkin, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, M. V. Mayevskaya, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda

“…Groups differed in relation to received drug and hepatitis C virus genotype. All patients received 1,5 mkg per 1 kg body weight per week of Pegaltevir or PegIntron and 800–1400 mg of ribavirin per day. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…Knockdown of Blimp-1 by macrophage-targeted adeno-associated virus in this model resulted in decreased survival rates, exacerbated tissue damage, and impaired M2 polarization, underscoring its protective role in sepsis. …”
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von Willebrand factor polymorphism (rs1063856) as a risk factor for portal vein thrombosis in chronic liver diseases by Isis Samy Bedira, Olfat M. Hendy, Moones Abdelaal, Ashraf A. Basuni, Asma Ebrahim Gaber Koshoo, Alzhraa Alkhatib, Sally S. Mandour

“…Tests for liver and renal function, coagulation profile, complete blood count, hepatitis virus markers, and vWF:Ag level were conducted. The identification of the vWF gene polymorphism (rs1063856) was assessed using real-time PCR. …”
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Lack of Tissue Virological Response as a Predictor of Relapse in Chronic Hepatitis D after Completion Bulevirtide Therapy by P. O. Bogomolov, N. A. Shub, N. A. Gasilova, A. A. Belyakova, T. G. Lidzhieva, E. A. Kondrasheva, N. A. Barsukova, M. V. Arapova, E. A. Isaeva, S. V. Koblov, M. V. Kalashnikov, O. S. Kuzymina, A. Yu. Demyanov, A. O. Bueverov, I. V. Maev

“…Aim: to evaluate the significance of a positive polymerase chain reaction result for hepatitis D virus RNA (HDV RNA) in liver biopsy specimens of patients with chronic hepatitis D (CHD) after completion of antiviral therapy (AVT) as a predictor of infection relapse.Materials and methods. …”
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A network medicine approach to investigating ME/CFS pathogenesis in severely ill patients: a pilot study by Li-Yuan Hung, Chan-Shuo Wu, Chia-Jung Chang, Peng Li, Kimberly Hicks, Joshua J. Dibble, Braxton Morrison, Chimere L. Smith, Ronald W. Davis, Wenzhong Xiao

“…Our pathway analysis revealed potential associations between ME/CFS and conditions such as COVID-19, Epstein–Barr virus (EBV) infection, neurodegenerative diseases, and pathways involved in cortisol synthesis and secretion, supporting the hypothesis that ME/CFS is a neuroimmune disorder. …”
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