48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse by Wen-xiong Xu, Qian Zhang, Xiang Zhu, Chao-shuang Lin, You-ming Chen, Hong Deng, Yong-yu Mei, Zhi-xin Zhao, Dong-ying Xie, Zhi-liang Gao, Chan Xie, Liang Peng

“…Age, HBsAg level, and origin HBeAg status can be predictive factors for virologic relapse. The study was submitted to ClinicalTrials.gov Protocol Registration and Results System with the assigned NCT ID NCT02883647.…”
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Optimizing Hepatitis C Therapy in HIV/hepatitis C Virus (HCV) Coinfected Patients: Analysis of HCV Viral Kinetics on Treatment by Paul Damien James, David KH Wong

“…INTRODUCTION: Hepatitis C virus (HCV) infection is potentially curable, but the sustained virological response (SVR) has been shown to be lower in patients coinfected HIV. …”
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Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C by Louis WC Liu, George Tomlinson, Tony Mazzulli, Alison Murray, Jenny Heathcote

“…Furthermore, less than 50% of patients overall have a sustained virological response (SVR).…”
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SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject by R. Wumba, M. Mandina, Y. Nlandu, J. R. Makulo, A. Tshimpi, P. Mbala, A. Mbangama, P. Kabututu, J. M. Kayembe

“…Through a documentary review of literature, the authors describe virological and molecular aspects of SARS-CoV-2, the intimate mechanisms of cell infection, and potential therapeutic targets. …”
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Interferon Treatment of Hepatitis C Reinfection after Liver Transplantation: A Meta-Analysis by Yaqin Chen, Gang Wu, Hongmin Zhang, Hua Xu, Hong Li, Ling Chen, Yixuan Yang, Peng Hu, Dazhi Zhang, Hong Ren, Huaidong Hu

“…The treatment group was found to have higher virological response (VR) rates than controls at 12, 24, 48, and 72 weeks. …”
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Influenza Surveillance in an Urban Area by W Paul Glezen

“…In Houston the yearly influenza epidemics have been defined virologically by community surveillance obtained by testing specimens submitted from patients with acute respiratory illnesses seen by sentinel physicians. …”
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HIV RNA Suppression and Immune Restoration: Can We Do Better? by Marilia Rita Pinzone, Michelino Di Rosa, Bruno Cacopardo, Giuseppe Nunnari

“…HAART has significantly changed the natural history of HIV infection: patients receiving antiretrovirals are usually able to control viremia, even though not all virological responders adequately recover their CD4+ count. …”
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Clinical Recommendations for the Use of Recombinant Human Erythropoietin in Patients with Hepatitis C Virus Being Treated with Ribavirin by Morris Sherman, Lawrence Cohen, Mary Anne Cooper, Magdy Elkashab, Victor Feinman, David Fletcher, Nigel Girgrah, Jenny Heathcote, Mark Levstik, William B McNaull, David Wong, Florence Wong, Colina Yim

“…Today, combination antiviral therapy with pegylated interferon-alpha and ribavirin (RBV) allows many patients infected with hepatitis C virus (HCV) to achieve a sustained virological response, which is equivalent to cure. Data also support the clinical benefit of combination antiviral therapy in patients coinfected with HCV and HIV, and in patients who have received a liver transplant.…”
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Efficacy and safety of 3D-therapy at HCV-related subcompensated liver cirrhosis (genotype 1b) by P. O. Bogomolov, M. V. Matsiyevich, A. O. Buyeverov, V. D. Beznosenko, Ye. V. Fedosova, M. Yu. Petrachenkova, S. V. Koblov, K. Yu. Kokina, O. S. Kuzmina, N. V. Voronkova

“…The causes of inefficacy of previous modes of combined antiviral therapy (CAT) included absence of virologic response in 43.9% of the cases, recurrence of HCV replication - in 30.3%, virological breakthrough - in 16.7%, development of serious adverse effects - in 9.1%. …”
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Impact of Pentoxifylline and Vitamin E on Ribavirin-Induced Haemolytic Anaemia in Chronic Hepatitis C Patients: An Egyptian Survey by M. Assem, M. Yousri

“…Pentoxifylline and vitamin E can ameliorate RBV-associated haemolysis; improve compliance and virologic clearance when combined with the standard antiviral therapy in patients with chronic hepatitis C.…”
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Nucleoside analogues in treatment of liver cirrhosis as an outcome of chronic hepatitis B by I. G. Bakulin

“…Terms of lamivudine treatment for patients with liver cirrhosis should be no less than 22 months, and clearance HBV DNA is achieved in 93,9 % of patients. Sustained virologic response (it was assessed in 4 years after termination of treatment course) is estimated as 39%. …”
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Preliminary results of open comparative randomized study PHG-M3/P01-09 «ORION» on application of «Phosphogliv» in combined therapy of chronic hepatitis C by M. V. Mayevskaya

“…Analysis of cases with rapid virologic response (absence of HCV RNA or its level less than 750 copies/ml) within 4 wks of treatment has shown, that only the group phosphogliv/standard interferon α-2b/ribavirin included 3 such cases and that was especially important – all had the 1-st virus genotype. …”
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Evolution of Self-reported Neuropsychiatric Symptoms After Switching from Dolutegravir/Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide: Results from the Rand... by Barbara Rossetti, Micol Ferrara, Lucia Taramasso, Francesca Bai, Francesca Lombardi, Nicoletta Ciccarelli, Miriam Durante, Francesca Alladio, Federica Bonazza, Ilaria Rancan, Francesca Montagnani, Antonio Di Biagio, Antonella d’Arminio Monforte, Maurizio Zazzi, Massimiliano Fabbiani, for DOBINeuro study group

“…Switching from DTG/ABC/3TC to BIC/FTC/TAF in virologically suppressed PLWH was associated with an improvement in sleep disorders but not in any other neuropsychiatric symptom. …”
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Emergence of Mpox and new epidemics: psychological and social impact of stigma in communication and prevention by Giacomo Fiacco, Antonietta Grandinetti

“…In addition to the strictly virological and symptomatic aspects, there is a growing recognition of the need to address the psychological dimension of the patient. …”
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Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients by D. T. Abdurakhmanov, Ye. . Sidorova, I. N. Tikhonov, N. A. Mukhin, V. T. Ivashkin

“…Combined therapy by asunaprevir and daclatasvir for 24 weeks resulted in sustained virologic response. No significant adverse effects on drug to drug interactions, except for mild and controllable alteration of tacrolimus blood level, were noted. …”
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Interleukin 28B polymorphism impact on early HCV kinetics in HCV-infected liver transplant recipients undergoing antiviral therapy by V. E. Syutkin, V. P. Chulanov, I. V. Karandashova, V. A. Dolgin, A. O. Chugunov

“…To estimate the impact of recipient IL28B genotypes on rapid (RVR) and early virologic responses (EVR) pattern in liver transplant recipients undergoing antiviral treatment (AVT).Material and methods. …”
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Nucleos(t)ide Analog Treatment Discontinuation in Chronic Hepatitis B Virus Infection: A Systematic Literature Review by Robert Gish, Kosh Agarwal, Anadi Mahajan, Supriya Desai, Saifuddin Kharawala, Rob Elston, Joyeta Das, Stuart Kendrick, Vera Gielen

“…Cumulative rates of clinical relapse (40 studies), virological relapse (53 studies), biochemical relapse (10 studies) and retreatment events (14 studies) post NA cessation varied widely across studies (clinical relapse: 40%–65%, virological relapse: 75%–94%, biochemical relapse: 63%–73%, retreatment rates: 30%–78% at 24 and 144 weeks, respectively). …”
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HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique by Nalia Ismael, Cidia Hussein, Cacildo Magul, Humberto Inguane, Aleny Couto, Amancio Nhangave, Ana Muteerwa, Mahoudo Bonou, Artur Ramos, Peter Wesley Young, Sonia Chilundo, Rhoderick Machekano, Lauren Greenberg, Juliana da Silva, Nilesh Bhatt

“…We assessed HIVDR rates and patterns in clients with virological failure (VF) after switching from an NNRTI-based regimen to TLD. …”
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Patient Care and Support Measures Overcome Reluctance to Initiate New Regimen Containing Enfuvirtide by Benoit Trottier

“…The patient’s acceptance was enhanced by the use of a needle-free injection system (Biojector), with minimal side effects and significantly improved virological and immunological control.…”
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Sociology of the COVID-19 Lockdown: Critical Analysis of Its Effects on Private School Teacher Wellbeing by Denis, Sekiwu, Johnson, Ocan

“…Much of the research on COVID-19 is gleaned on epidemiological, virological, and medical outcomes of the global pandemic. …”
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