Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study by Francesca Pancrazi, Omar De Bei, Francesco Lavecchia di Tocco, Marialaura Marchetti, Barbara Campanini, Salvatore Cannistraro, Stefano Bettati, Anna Rita Bizzarri

“…Abstract Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven virulence factor that can be targeted for the design of antibacterial molecules or vaccines. Recent single-molecule experiments on IsdB interaction with cell adhesion factors revealed an increase of the complex lifetime upon applying a stronger force (catch bond); this was suggested to favor host invasion under shear stress. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…MAGEA4-based TCR-T cell therapy and cancer vaccines show clinical potential. This article comprehensively reviews the structure and function of MAGEA4, as well as recent research progress in solid tumors, providing a theoretical foundation for the clinical translation of MAGEA4 and its application in immunotherapy.…”
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Monoclonal Antibodies in Prevention and Early Treatment of COVID-19 in Lung Transplant Recipients: A Systematic Review and Perspective on the Role of Monoclonal Antibodies in the F... by David A. Van Eijndhoven, Robin Vos, Robin Vos, Saskia Bos, Saskia Bos

“…Coronavirus disease 2019 (COVID-19) has significantly impacted lung transplant recipients (LTR), who remain vulnerable to severe COVID-19 despite vaccination, prompting the use of monoclonal antibodies (mAbs) as a treatment option. …”
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Mathematical Modelling of Cholera Transmission incorporating Media Coverage. by Muhereza, Obed

“…Since cholera spreads and kills very fast, the effectiveness of control strategies such as vaccination, water chlorination and therapeutic treatment may be enhanced by the use of media alert and awareness campaigns. …”
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Optimal control analysis of Taenia saginata bovine cysticercosis and human taeniasis by Damian, Kajunguri, Joshua, A. Mwasunda, Jacob I, Irunde

“…The optimal control theory is applied by considering three time dependent controls which are improved meat cooking, vaccination of cattle, and treatment of humans with taeniasis when they are implemented in combination. …”
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Rapid aging of influenza epidemics in China from 2005/06 to 2016/17: A population-based study by Weibo Tang, Hao Lei, Nan Zhang, Yaojing Wang, Shimeng Cai, Shuyi Ji, Lei Yang, Mengya Yang, Can Chen, Shigui Yang, Dayan Wang, Yuelong Shu

“…This finding highlights the importance of influenza vaccination among older individuals in China.…”
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The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review by Asma D. Alshammari, Mona Matar Aldhafeeri, Amal M. Aldhafeeri, Maram Asaad Alanzi, Maha Bandar Almutairi, Jawaher Abdullah Alrasheedi, Thikra Adel Alsurur, Aeshah Dhahawi Alshammri

“…Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. …”
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Infection Dynamics of Severe Acute Respiratory Syndrome Coronavirus-2 Wild-type and Delta Variant of Concern in a Pediatric Cohort in Southern India by Asha Jyothi Penugonda, Deepayan Biswas, Murugan Thimiri Palani, Sangeetha Priya, Rajesh Kumar Subaschandrabose, Koshy Alan Valiaveetil, Belavendra Antonisamy, Rajeev Zachariah Kompithra, Leni Grace Mathew, Mahesh Moorthy

“…These results could inform potential responses to future SARS-CoV-2 variants and may guide decisions on targeted vaccination in children.…”
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Armed violent conflict and healthcare-seeking behavior for maternal and child health in sub-Saharan Africa: A systematic review. by Gbadebo Collins Adeyanju, Pia Schrage, Rabiu Ibrahim Jalo, Liliana Abreu, Max Schaub

“…Nine studies (42.8%) observed behaviors for child health such as vaccination uptake, case management for pneumonia, diarrhea, malnutrition, and cough. …”
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Impact of Social Assistance Grants for Empowerment on Standards of Living of Elderly Persons in Kabale Municipality Kabale District. by Naturinda, Suzan

“…The study results on the effect of social assistance grants for empowerment on the health of the elderly in Kabale Municipality, the highest number of respondents mentioned that social assistance grants for empowerment can help to alleviate financial stress which leads to better physical health outcomes for elderly persons while the least number of respondents mentioned that social assistance grants for empowerment help elderly individuals stay healthy since they can be able to purchase vaccines and have good health. The study findings on the effect of social assistance grants for empowerment on the consumption of elderly in Kabale Municipality, the highest number of respondents mentioned that social assistance grants for empowerment can alleviate financial stress and uncertainty for elderly individuals, allowing them to budget more effectively and plan for future consumption needs while the least number of respondents mentioned that social assistance grants for empowerment allows elderly persons to allocate more of their funds towards consumption for better health. …”
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Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

“…BV activation of the cellular and humoral immune systems should be explored for the application of complementary medicine for the management of SARS-CoV-2 infections. BV “vaccination” is used to immunize against cytomegalovirus and can suppress metastases through the PLA2 and phosphatidylinositol-(3,4)-bisphosphate pathways. …”
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Prevalence and correlates of facemask usage during the second wave of COVID-19 pandemic in Uganda. by Nelson Onira Alema, Christopher Okot, Emmanuel Olal, Eric Nzirakaindi Ikoona, Freddy Wathum Drinkwater Oyat, Steven Baguma, Denish Omoya Ochula, Patrick Odong Olwedo, Johnson Nyeko Oloya, Francis Pebalo Pebolo, Pamela Okot Atim, Godfrey Smart Okot, Ritah Nantale, Judith Aloyo, David Lagoro Kitara

“…We conducted a cross-sectional study on 587 adults across nine districts in northern Uganda, across 24 high-volume health facilities offering free COVID-9 vaccines. Respondents were selected from the health facilities using a single-stage systematic sampling method. …”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Innovative immunotherapy modalities, including adoptive immune cell therapy, tumor vaccines, and non-specific immunomodulators therapy, and oncolytic viruses have shown promise in early-stage clinical trials for GC. …”
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Effect of Household Income on Household Welfare in Kitumba Sub-County Kabale District. by Kakuru, Richard

“…In the study findings on the effect of household income on health accessibility in Kitumba sub-county Kabale District, the highest number of respondents mentioned that households with higher income are more likely to afford regular health check-ups, vaccinations, and preventive screenings, which can detect and address health issues early while the least number of respondents mentioned that higher-income households can more easily afford consultation fees, treatment costs, and surgical procedures, whereas lower-income families might struggle to pay for even basic healthcare services. …”
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Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran by Jafar Sadegh Tabrizi, Mondher Letaief, Hossein Mashhadi Abdolahi, Ramin Rezapour, Ahmed Alboksmaty, Mostafa Farahbakhsh

“…Most of HWs had completed the full vaccination schedule for Hepatitis B and COVID-19. Personal Protective Equipment (PPE) safety protocols were adhered by most of HWs within a healthcare facility. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…The clinical severity of different variants was assessed in relation to patient sex, age, clinical classification, and vaccination status.ResultsBetween Week 1 of 2023 and Week 11 of 2024, a total of 5,965 complete SARS-CoV-2 genome sequences were obtained, including 3,004 male (50.36%) and 2,961 female (49.64%) cases. …”
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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

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Social network analysis of key stakeholders in Brucellosis prevention in Western Iran by Meysam Behzadifar, Mohammad Yarahmadi, Ahad Bakhtiari, Sahar Kargar, Saeed Shahabi, Samad Azari, Mariano Martini, Masoud Behzadifar

“…Economic constraints, such as the high cost of vaccines, along with limited public awareness, further hinder effective control efforts. …”
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Is differential cleaning needed for SARS-CoV-2 beyond standard procedures? A systematic review by Uduak Okomo, Ememobong N. Aquaisua, Osamagbe Asemota, Deborah Ndukwu, Josephine E. Egbung, Ekpereonne B. Esu, Olabisi A. Oduwole, John E. Ehiri

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Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria by Esther Oluwakemi Oluwole, Alero Ann Roberts, Ifeoma Peace Okafor, Victoria Oluwasola Yesufu

“…Notably, 86% attended postnatal care services primarily for child vaccination. Christian religion (adjusted odds ratio (AOR): 1.810; confidence interval (CI): 0.989–3.313), self-employment status of spouses (AOR: 2.949: CI: 1.413–6.153), and household monthly income above 60,000.00 naira (AOR: 2.015; CI: 1.002–4.005) were predictors for ANC use. …”
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