Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

Subjects: “…Tick-borne diseases, Anaplasma ovis, Parasites Small ruminants, Goats Uganda Africa, Ticks Tick resistance, Tick vaccines, Entomology, Ecosystem services, Protozoa Polymerase chain reaction, Epidemiology Veterinary medicine, Animal behavior, Animal breeding, Ruminant Agriculture.…”
Get full text

Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda by Keneth Iceland, Kasozi, Susan Christina, Welburn

Subjects: “…Tick-borne diseases Anaplasma ovis Parasites Small ruminants Goats Uganda Africa Ticks Tick resistance Tick vaccines Entomology Ecosystem services Protozoa Polymerase chain reaction Epidemiology Veterinary medicine Animal behavior Animal breeding Ruminant Agriculture…”
Get full text

Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…npj Vaccines…”
Get full text

QAAPT: an interoperable web-based open-source tool for antimicrobial resistance data analysis and visualisation by Mohammad Julhas Sujan, Sanjay Gautam, Ahmed Taha Aboushady, Adam Clark, Sooyoung Kwon, Hea Sun Joh, Marianne Holm, John Stelling, Florian Marks, Florian Marks, Florian Marks, Florian Marks, Nimesh Poudyal

“…The QAAPT tool was created by the Capturing Data on Antimicrobial Resistance Patterns and Trends in Use in Regions of Asia project, led by the International Vaccine Institute (IVI). This open-source web-based tool/application generates statistical and visual outputs of AMR data, offers data curation options, and can be integrated with laboratory information management systems. …”
Get full text

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane by Kathryn M. Hastie, Zhe Li Salie, Zunlong Ke, Peter J. Halfmann, Lisa Evans DeWald, Sara McArdle, Ariadna Grinyó, Edgar Davidson, Sharon L. Schendel, Chitra Hariharan, Michael J. Norris, Xiaoying Yu, Chakravarthy Chennareddy, Xiaoli Xiong, Megan Heinrich, Michael R. Holbrook, Benjamin Doranz, Ian Crozier, Yoshihiro Kawaoka, Luis M. Branco, Jens H. Kuhn, John A. G. Briggs, Gabriella Worwa, Carl W. Davis, Rafi Ahmed, Erica Ollmann Saphire

“…The findings reported here can guide design of next-generation highly potent anti-EBOV therapeutics and vaccines.…”
Get full text

Recent advances of nanovaccines on cancer theranostics by Xiaobing Yuan, Xiaobing Yuan, Xiaobing Yuan, Tianyou Xu, Mubashir Hussain, Bin Liu, Jianwei Zhu, Jianwei Zhu

“…This paper reviewed the research progress of some nanovaccines in cancer immunotherapy, including polymer nanoparticle vaccine, liposome nanoparticle vaccine, cell-based nanoparticle vaccine, inorganic nanoparticle vaccine, adjuvant and auxiliary work. …”
Get full text

Global progress, challenges and strategies in eliminating public threat of viral hepatitis by Sihui Zhang, Fuqiang Cui

“…While improving the coverage of vaccine use, drugs for treating hepatitis B are not only becoming more effective, but also decreasing in price. …”
Get full text

A Mathematical Model for the Dynamics of Polio by Johnan, Owobusingye

Get full text

Awareness of medical students about standard isolation precautions In Sulaimani City by Bushra M. Ali, Saman A. Mohammed, Balen Tayb Abdullah, Osama Muhammed, Mutasam Fabian, Muhammed Rauf

“… The objectives of this study are to assess knowledge, Attitude and practice of medical students about standard isolation precautions and different college students and to identify those who vaccinated with HBV vaccine. A cross-sectional study was conducted from 27th of February 2019 till 1st of March 2019 in Sulaimani University among medical students .A convenient sample of 401 students were participated. …”
Get full text

A Mathematical Model For The Dynamics of Polio. by Owobusingye, Johnan

“…There is a lack of treatment for poliomyelitis and it is only prevented through immunization with live oral polio vaccine (OPV) or/and inactivated polio vaccine (IPV). …”
Get full text

RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…Importantly, the induced antibodies effectively inhibited the binding of RBD to human angiotensin-converting enzyme 2 (hACE2) and neutralized SARS-CoV-2 pseudoviruses. Conclusions This vaccine platform offers an alternative strategy for developing recombinant subunit vaccines against SARS-CoV-2, potentially enhancing immune responses and improving vaccine efficacy. …”
Get full text

ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

Get full text

CD16 and CD57 expressing gamma delta T cells in acute HIV-1 infection are associated with the development of neutralization breadth. by Gina L Griffith, Kawthar Machmach, Ningbo Jian, Dohoon Kim, Margaret C Costanzo, Matthew Creegan, Isabella Swafford, Gautam Kundu, Lauren Yum, Jessica S Bolton, Lauren Smith, Bonnie M Slike, Elke S Bergmann-Leitner, Rasmi Thomas, Nelson L Michael, Julie A Ake, Leigh Anne Eller, Merlin L Robb, Samantha M Townsley, Shelly J Krebs, Dominic Paquin-Proulx, RV217 Study Group

“…New HIV vaccine approaches are focused on eliciting broadly neutralizing antibodies. …”
Get full text

Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation. by Louis Kuijpers, Evdokia-Anastasia Giannopoulou, Yuzhen Feng, Wouter van den Braak, Abbas Freydoonian, Ramon Ramlal, Hugo Meiring, Belén Solano, Wouter H Roos, Arjen J Jakobi, Leo A van der Pol, Nynke H Dekker

“…To counteract hand, foot, and mouth disease-causing viruses such as enterovirus A71 and coxsackievirus A6, virus-like particles (VLPs) have emerged as a leading contender for the development of a multivalent vaccine. However, VLPs have shown rapid conversion from a highly immunogenic state to a less immunogenic state and low particle integrity lifetimes compared to inactivated virus vaccines, thus raising concerns about their overall stability. …”
Get full text

Unvaccinated COVID-19 Pneumonia- a family affair by Trilok Stead, Michael Hughes, Frank Fraunfelter, Vashun Rodriguez, Latha Ganti

“…This case illustrates the complexities of vaccine hesitancy and societal misinformation.…”
Get full text

Leveraging Quantum LSTM for High-Accuracy Prediction of Viral Mutations by Prashanth Choppara, Bommareddy Lokesh

“…The rapid mutations of viruses such as COVID-19 pose significant challenges for vaccine development and effective disease management. …”
Get full text

Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthoha... by Jing Wei, Hui Zhang, Jiawei Pei, Qiqi Yang, Yuan Wang, Xiaolei Jin, He Liu, Liang Zhang, Hongwei Ma, Linfeng Cheng, Yangchao Dong, Yingfeng Lei, Yinlan Bai, Zhikai Xu, Pengbo Yu, Fanglin Zhang, Wei Ye

“…Currently, the inactive vaccine licensed in endemic areas elicit low levels of neutralizing antibodies (NAbs). …”
Get full text

Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens by Jie Jiang, Feng-Ying Huang, Shu-Zhen Dai, Guang-Hong Tan, Ming-Hui Chen, Hengyu Chen, Wu-Ping Zheng, Ri-Hong Wu, Weijing Xie

“…Additionally, vaccination with phMTb-formulated neoantigen vaccines effectively reversed the tumor’s immune-suppressive microenvironment. …”
Get full text

Analysis and Characterization of the Immunogenicity of Rhoptry Protein 18 by Masoud Foroutan, Amir Karimipour-Saryazdi, Ali Dalir Ghaffari, Hamidreza Majidiani, Arezo Arzani Birgani, Elaheh Karimzadeh-Soureshjani, Shahrzad Soltani, Hany M Elsheikha

“…Due to its potential as a vaccine candidate, this study aimed to characterize several properties of the T. gondii ROP18 (TgROP18) protein to support its inclusion in vaccine formulations. …”
Get full text

Factors Affecting Immunization Coverage for Children Under Five Years in Rwanyamahembe Sub-County, Mbarara District- Uganda. by Omia, Santos

“…The study further identified inadequate funding of the program, perceived shortage of staff, cost of vaccination and vaccination cards, inadequate supply of vaccine stock, inadequate vaccination sites and corruption and embezzlement of funds as the main institutional factors affecting with EPI service coverage. …”
Get full text