Antioxidant and Antihyperglycemic Properties of Three Banana Cultivars (Musa spp.) by Bukola C. Adedayo, Ganiyu Oboh, Sunday I. Oyeleye, Tosin A. Olasehinde

“…The low sugar, GI, amylose, and amylopectin contents of the three banana cultivars as well as their α-amylase and α-glucosidase inhibitory activities could be possible mechanisms and justification for their recommendation in the management of type-2 diabetes.…”
Get full text

The Role of Oral Biomarkers in the Assessment of Noncommunicable Diseases by Gustavo Sáenz-Ravello, Marcela Hernández, Mauricio Baeza, Patricia Hernández-Ríos

“…Key studies were analyzed to identify associations between oral biomarkers and systemic diseases such as cardiovascular diseases, type 2 diabetes mellitus, autoimmune disorders, and cancers. …”
Get full text

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study by Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker

“…The study found no significant difference in AMD incidence between the sildenafil users and the non-users, with an adjusted hazard ratio (HR) of 0.99 (95% CI 0.84 to 1.16), after accounting for confounders such as age, ethnicity, Townsend deprivation quintile, body mass index category, and diagnosis of hypertension and type 2 diabetes.Conclusion The study results indicated no significant association between sildenafil use and AMD prevention in UK men with erectile dysfunction, suggesting sildenafil’s protective effect on AMD is likely insignificant.…”
Get full text

The Change of Skeletal Muscle Caused by Inflammation in Obesity as the Key Path to Fibrosis: Thoughts on Mechanisms and Intervention Strategies by Yixuan Li, Wenwen Guo, Han Li, Yuhao Wang, Xinwei Liu, Wen Kong

“…Meanwhile, obesity is closely related to the development of skeletal muscle fibrosis and can affect the metabolic function of skeletal muscle, triggering metabolic disorders such as insulin resistance (IR) and type 2 diabetes (T2D). However, whether there is a mutual regulatory effect between the two pathological states of inflammation and fibrosis in obese skeletal muscle and the specific molecular mechanisms have not been fully clarified. …”
Get full text

Effects of natural products on macrophage immunometabolism: A new frontier in the treatment of metabolic diseases by Jiani Li, Chen Guo, Xiaofei Yang, Weinan Xie, Wenjing Mi, Chenglong Hua, Cheng Tang, Han Wang

“…Dysregulation of macrophage immunometabolism has been closely implicated in several metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), hypertension, atherosclerosis, and gout, which positions macrophages as potential therapeutic targets. …”
Get full text

Prolonged exposure to insulin might cause epigenetic alteration leading to insulin resistance by Shehnaz Bano, Shyam More, Dattatray S. Mongad, Abdul Khalique, Dhiraj P. Dhotre, Manoj K. Bhat, Vasudevan Seshadri

“…Hyperinsulinemia often precedes insulin resistance and Type 2 diabetes. We had previously shown that prolonged exposure of insulin‐responsive cells to insulin in the absence of high levels of glucose led to insulin resistance. …”
Get full text

Does task delegation to non-physician health professionals improve quality of diabetes care? Results of a scoping review. by Sanas Mirhoseiny, Tjarko Geelvink, Stephan Martin, Horst Christian Vollmar, Stephanie Stock, Marcus Redaelli

“…Most of the interventions were performed in an outpatient setting with type-2 diabetes mellitus patients. The non-physician healthcare professionals involved in the team were nurses, pharmacists, community health workers and dietitians. …”
Get full text

Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment by Quan Xing, Jingyi Feng, Xiaolei Zhang

“…However, high-glucose (HG) conditions in type 2 diabetes mellitus (T2DM) exert deleterious effects on BMSC proliferation and osteogenic differentiation. …”
Get full text

Evaluation of the Association Metformin: Plantago ovata Husk in Diabetic Rabbits by Raquel Díez-Láiz, Juan J. García-Vieitez, M. José Diez-Liébana, Matilde Sierra-Vega, Ana M. Sahagún-Prieto, Ángela P. Calle-Pardo, Nélida Fernández-Martínez

“…We conclude that Plantago ovata husk intake can contribute to the oral antihyperglycemic treatment of type 2 diabetes.…”
Get full text

Prevalence of metabolic syndrome and its risk factors among the government bank’s employees of district Bijnor, Uttar Pradesh: A cross-sectional study by Ajay Kumar Prajapati, Ruchi Prajapati

“…Background: Metabolic syndrome (MetS) involves having at least 3 out of 5 health conditions that increase the risk of cardiovascular disease, stroke, and type 2 diabetes mellitus. These conditions include increased blood pressure (BP), high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels. …”
Get full text

Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes by Alessandro P. Delitala, Giovanni M. Pes, Hoda M. Malaty, Gavino Pisanu, Giuseppe Delitala, Maria P. Dore

“…Type 1 diabetes (T1D) and type 2 diabetes (T2D) have been linked to Helicobacter pylori infection, although results are conflicting. …”
Get full text

The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications by Ranin Saad, Hagar Tadmor, Offir Ertracht, Nakhoul Nakhoul, Farid Nakhoul, Farber Evgeny, Shaul Atar

“…Background. Type 2 diabetes mellitus (T2DM), especially hyperglycemia, is associated with increased glucose cell toxicity and oxidative stress that can lead to irreversible damage in the kidney such as diabetic nephropathy (DN). …”
Get full text

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes by Samira Mukhtar Buzinin, Aied Mohammed Alabsi, Alexander Tong Boon Tan, Vui King Vincent-Chong, Dasan Swaminathan

“…Most of the researches linking these two very common chronic diseases were based on type 2 diabetes mellitus and chronic periodontal disease. …”
Get full text

Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II by Yaodu Wang, Zhiyang Wu, Likuan Hu

“…We collected specimens and evaluated clinicopathological parameters of 102 stage I to III CRC patients with prediagnosed type 2 diabetes mellitus (DM II). Expression of E-cadherin and vimentin in tumors was detected by immunohistochemistry (IHC), and statistical analysis was performed using SPSS 19.0. …”
Get full text

Electrodiagnostic assessment of autonomic nervous system in diabetic autonomic neuropathy: Case series in 72 diabetes patients by Suchitra Dube, Sandip M. Hulke, Santosh L. Wakode, Sagar Khadanga

“…Seventy-two diagnosed Type-2 Diabetes mellitus patients were examined using POWER LAB AND LAB CHART 8 BY AD INSTRUMENT: For recording heart rate variability (HRV) and Ewing’s battery of tests: For Autonomic function testing. …”
Get full text

Development and Validation of a Food Frequency Questionnaire for Dietary Antioxidant Intake among Prediabetic Individuals in the South Indian Population by Sowmya R, Supriya V, Rajkumar M, Silambuselvi K

“… Background: Prediabetes is a growing global public health concern, with dietary factors playing a major role in its progression to type 2 diabetes. Antioxidants can mitigate oxidative stress, a major contributor to prediabetes. …”
Get full text

Metformin: A Potential Drug for COVID-19 by Anjali Devi Bettadapura Shankara Rao, Sujatha Puttalingaiah, Ananth B Koushik, Jadeppa Gowda

“…Metformin is an old drug, of plant origin, primarily used in the treatment of type 2 diabetes. The main mechanism of its action is mediated through adenosine monophosphate (AMP) kinase. …”
Get full text

Short-Term Exercise Training Improves Insulin Sensitivity but Does Not Inhibit Inflammatory Pathways in Immune Cells from Insulin-Resistant Subjects by Sara M. Reyna, Puntip Tantiwong, Eugenio Cersosimo, Ralph A. DeFronzo, Apiradee Sriwijitkamol, Nicolas Musi

“…TLR4 content and ERK phosphorylation are increased in PMNC of type 2 diabetic individuals. While exercise improves insulin sensitivity, this effect is not related to changes in TLR2/TLR4 content or ERK phosphorylation in PMNC of type 2 diabetic individuals.…”
Get full text

The Utility of Perirenal Fat in Determining the Risk of Onset and Progression of Diabetic Kidney Disease by Hongtu Hu, Wei Liang, Zongwei Zhang, Zikang Liu, Fan Chu, Yan Bao, Jialu Ran, Guohua Ding

“…In the cross-sectional analysis, we screened 959 patients from 8764 subjects with type 2 diabetes mellitus (T2DM) who met the inclusion criteria and measured their perirenal fat thickness (PFT) using color Doppler ultrasound. …”
Get full text

Metformin-Associated Acute Kidney Injury and Lactic Acidosis by David Arroyo, Rosa Melero, Nayara Panizo, Marian Goicoechea, Patrocinio Rodríguez-Benítez, Soledad García Vinuesa, Eduardo Verde, Alberto Tejedor, José Luño

“…Metformin is the preferred oral antidiabetic agent for type 2 diabetes. Lactic acidosis is described as a rare complication, usually during an acute kidney injury (AKI). …”
Get full text