Extending TextAE for annotation of non-contiguous entities by Jake Lever, Russ Altman, Jin-Dong Kim

“…., the entity “type 1 diabetes” in the phrase “type 1 and type 2 diabetes.” This type is commonly found in biomedical texts, especially in lists, where multiple biomedical entities are named in shortened form to avoid repeating words. …”
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Obesity Related Alterations in Plasma Cytokines and Metabolic Hormones in Chimpanzees by Pramod Nehete, Elizabeth R. Magden, Bharti Nehete, Patrick W. Hanley, Christian R. Abee

“…Obesity is characterized by chronic low-grade inflammation and serves as a major risk factor for hypertension, coronary artery disease, dyslipidemias, and type-2 diabetes. The purpose of this study was to examine changes in metabolic hormones, inflammatory cytokines, and immune function, in lean, overweight, and obese chimpanzees in a controlled environment. …”
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A trend of osteocalcin in diabetes mellitus research: bibliometric and visualization analysis by Zixu Liu, Zixu Liu, Yuchen Mao, Kangping Yang, Shukai Wang, Fang Zou

“…The proposed focus areas are “osteocalcin genes”, “insulin regulation and osteoporosis “, “different populations”, “diabetes-related complications” and “type 2 diabetes mellitus”,“effect of osteocalcin expression on insulin sensitivity as well as secretion”,“osteocalcin expression in different populations of diabetic patients and treatment-related studies”.…”
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Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range by Lindor Gelin, Jiewen Li, Kathryn L. Corbin, Ishrat Jahan, Craig S. Nunemaker

“…Metformin is considered the first-line treatment for type 2 diabetes. While metformin primarily increases insulin sensitivity, evidence also suggests that metformin affects the activity of insulin-secreting pancreatic islets. …”
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Mechanistic insights toward progress in alogliptin beyond glycemic control: translational perspective by Faraha Ahmed, Syed Sufian Ahmad, M. Mumtaz Alam, M. Shaqiquzzaman, Abul Kalam Najmi, Mohammad Ahmed Khan

“…Main body Alogliptin is approved for treatment of type 2 diabetes mellitus (T2DM) in majority of the countries. …”
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Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions by M. Snel, J. T. Jonker, J. Schoones, H. Lamb, A. de Roos, H. Pijl, J. W. A. Smit, A. E. Meinders, I. M. Jazet

“…Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM). Not the triglycerides per se but the accumulation of intermediates of lipid metabolism in organs, such as the liver, skeletal muscle, and heart seem to disrupt metabolic processes and impair organ function. …”
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Engaging with patients with diabetes: the role of social media in low-income healthcare organisations by Jose Rodriguez, Shabbir Syed-Abdul, Andrea Cano, Mohy Uddin, Fernanda Caceres

“…Background Type 2 diabetes is the fastest-growing global health concern, and its global prevalence is projected to affect 643 million individuals by 2030. …”
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Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration by Camille Green, Vandana Zaman, Kayce Blumenstock, Narendra L. Banik, Azizul Haque

“…The role of metabolic peptides in the development and potentially reversal of diseases such as obesity, hyperinsulinemia, and type 2 diabetes will also be discussed. Furthermore, we review the potential links between these conditions and neuroinflammation and the development of neurodegenerative diseases like dementia, specifically Parkinson’s disease and Alzheimer’s disease.…”
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Diabetic microangiopathies: mechanisms of development, approaches to the therapy by Birukova E.V, Shinkin M.V.

“…DR is diagnosed in almost all the patients with type 1 diabetes and in 60% of patients with type 2 diabetes with a duration of the disease of more than 20 years.…”
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Diagnostic Challenge in a Patient with Severe Anion Gap Metabolic Acidosis by Eugene M. Tan, Ejaaz Kalimullah, M. Rizwan Sohail, Kannan Ramar

“…We present a 76-year-old female with type 2 diabetes mellitus, who was found at home in a confused state. …”
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Utility of Tetrahydrobiopterin Pathway in the Assessment of Diabetic Foot Ulcer: Significant and Complex Interrelations by Marwan Al-Nimer, Rawa Ratha, Taha Mahwi

“…Tetrahydrobiopterin (BH4) pathway that included generation of neopterin (Neop), biopterin (Biop), and nitric oxide (NO) is altered in type 2 diabetes (T2D). The aim of this study was to assess the biomarkers of BH4 pathway in noninfected DFUs and to relate these levels to the variables of diabetes as well as to the hematological indices. …”
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Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRIN-BD11 by Kateryna Pierzynowska, Stina Oredsson, Stefan Pierzynowski

“…Blood glucose, plasma insulin, and glucagon levels were measured following a duodenal glucose tolerance test (IDGTT), in four pigs with STZ-induced type 2 diabetes (T2D pigs) and in four pigs with STZ-induced type 1 diabetes (T1D pigs). …”
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Diabetes Risk Score in a Young Student Population in Jordan: A Cross-Sectional Study by Abdel-Ellah Al-Shudifat, Amjad Al-Shdaifat, Ahmad Ali Al-Abdouh, Mohammad Ibrahim Aburoman, Sara Mohammad Otoum, Amro Ghaleb Sweedan, Ibrahim Khrais, Ibrahim Hisham Abdel-Hafez, Asgeir Johannessen

“…The Middle East is the home to the most obese population in the world, and type 2 diabetes mellitus is endemic in the region. However, little is known about risk factors for diabetes in the younger age groups. …”
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The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM by Dandan Wang, Baiyu Shen, Chunrong Wu, Yanyan Xue, Yanjun Liu

“…This study aims to explore the relationship between autonomic nerve dysfunction—assessed by cardiovascular autonomic neuropathy risk score (CAN-RS)—and ocular abnormality in Chinese type 2 diabetes mellitus (T2DM). Method. This is a cross-sectional study. …”
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Preventive interventions for diabetic foot ulcer adopted in different healthcare settings: A scoping review protocol. by Açucena Leal de Araújo, Francisca Diana da Silva Negreiros, Raquel Sampaio Florêncio, Thiago Dos Santos Garces, Virna Ribeiro Feitosa Cestari, Samuel Miranda Mattos, Samara Jesus Sena Marques, Francisca Eridan Fonteles Albuquerque, Wánderson Cássio Oliveira Araújo, Vanessa de Brito Poveda, Thereza Maria Magalhães Moreira

“…Studies with participants diagnosed with type 1 and type 2 diabetes, aged 18 years or older, without an active ulcer at baseline, and studies of preventive interventions for foot ulcers in various healthcare settings will be screened. …”
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Performance Comparison of Two Gene Set Analysis Methods for Genome-wide Association Study Results: GSA-SNP vs i-GSEA4GWAS by Ji-sun Kwon, Jihye Kim, Dougu Nam, Sangsoo Kim

“…GSA runs were made with two sets of p-values from a Korean type 2 diabetes mellitus GWAS study: 259,188 and 1,152,947 SNPs of the original and imputed genotype datasets, respectively. …”
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Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D by Sameeah Abdulrahman Rashid

“…This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). …”
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Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α‑glucosidase inhibitors by Mehrdad Roshan, Roghieh Mirzazadeh, Azadeh Tajmir-Riahi, Mohammad Sadegh Asgari

“…The primary aim of this study was to explore the potential of novel pyrazole-phthalazine hybrids as selective inhibitors of α-glucosidase, an enzyme involved in carbohydrate metabolism, which plays a key role in the management of type 2 diabetes. The rationale for this study stems from the need for new, more effective inhibitors of α-glucosidase with improved efficacy and safety profiles compared to currently available therapies like Acarbose. …”
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Perception of the Importance of Inherited Genetics and Lifestyle on the Development of Chronic Diseases: A UK Cross‐Sectional Survey by Aamir Hussain, Lourdes Santos‐Merx, Mariasole Da Boit

“…Moreover, the majority of the respondents chose lifestyle over inherited genes as most important factor for cancer, cardiovascular disease and Type 2 Diabetes development (50.8% vs. 29.6%, 79% vs. 11.9%, 85.7% vs. 9.6%; respectively), while 60.6% of respondents selected inherited genes for rheumatoid arthritis (p < 0.05). …”
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Sweets and other sugary foods – a scoping review for Nordic Nutrition Recommendations 2023 by Henna Vepsäläinen, Emily Sonestedt

“…We found some evidence linking chocolate consumption with lower blood pressure, lower risk of type 2 diabetes, and improved insulin markers, but the evidence was ranked low or very low. …”
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