Stress in Obesity and Associated Metabolic and Cardiovascular Disorders by Paul Holvoet

“…Obesity has significant implications for healthcare, since it is a major risk factor for both type 2 diabetes and the metabolic syndrome. This syndrome is a common and complex disorder combining obesity, dyslipidemia, hypertension, and insulin resistance. …”
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Successful Use of Octreotide Therapy for Refractory Levofloxacin-Induced Hypoglycemia: A Case Report and Literature Review by Matthew R. Watson, Ceressa T. Ward, Amit Prabhakar, Babar Fiza, Vanessa Moll

“…We report a case of refractory fluoroquinolone-induced hypoglycemia in a patient with type-2 diabetes mellitus on glipizide that was successfully treated with octreotide. …”
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Leupaxin promotes hepatic gluconeogenesis and glucose metabolism by coactivation with hepatic nuclear factor 4α by Xiaomin Luo, Fang Liu, Lijun Zhu, Caizhi Liu, Ruhui Shen, Xiaoyin Ding, Yufan Wang, Xiaofang Tang, Yongde Peng, Zhijian Zhang

“…Abnormal gluconeogenesis in the liver can lead to hyperglycemia, a key diagnostic marker and the primary pathological contributor to type 2 diabetes (T2D) and metabolic disorders. Hepatic nuclear factor-4 (HNF4α) is an important regulator of gluconeogenesis. …”
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PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate by Robert I. Glazer, Hongyan Yuan, Zhihui Xie, Yuzhi Yin

“…PPARγ agonists are used by millions of people each year to treat type 2 diabetes but may also find additional utility as relatively nontoxic potentiators of chemotherapy. …”
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Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus by Lung-Wen Tsai, Yi-Hsiang Lu, Rajni Dubey, Jeng-Fong Chiou

“…Clinically, it has also been revealed that the existence of nonalcoholic fatty liver disease (NAFLD) enhances the incidence of type 2 diabetes mellitus (T2DM), while T2DM exacerbates NAFLD to extremely severe forms of steatohepatitis, cirrhosis, and hepatocellular carcinoma. …”
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Adropin as an indicator of T2DM and its complications by Hu Zhang, Ning Chen

“…Type 2 diabetes mellitus (T2DM) is one of metabolic diseases with the major inducer of obesity. …”
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A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications by Francesca Conserva, Loreto Gesualdo, Massimo Papale

“…Diabetic nephropathy (DN), a microvascular complication occurring in approximately 20–40% of patients with type 2 diabetes mellitus (T2DM), is characterized by the progressive impairment of glomerular filtration and the development of Kimmelstiel-Wilson lesions leading to end-stage renal failure (ESRD). …”
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Intrauterine Growth Retardation and Nonalcoholic Fatty Liver Disease in Children by Anna Alisi, Nadia Panera, Carlo Agostoni, Valerio Nobili

“…This study suggested that, in children, adolescents, and adults born SGA, insulin resistance could lead to other metabolic disorders: type 2 diabetes (DM2), dyslipidemia, and nonalcoholic fatty liver disease (NAFLD). …”
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Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review by Pan Gao, Han Yang, Han Yang, Zhi Zhang

“…This report describes a 54-year-old man with type 2 diabetes who presented with right lumbar pain and was diagnosed with EPN complicated by right ureteral calculi and perinephric gas accumulation. …”
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Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility by James Butterworth, Jean Deguara, Cynthia-Michelle Borg

“…Bariatric surgery has been shown to conclusively improve life expectancy, quality of life, and comorbidities like type 2 diabetes and obstructive sleep apnea. However, further research is required to identify whether weight loss surgery results in significant improvement in fertility of women with PCOS and to investigate which operation has the best results.…”
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Clinical condition of patients with Obesity Hypoventilation Syndrome (OHS): case report by Made Oka Heryana, Heru Widjono

“…We diagnosed her with obesity hypoventilation syndrome, type 2 diabetes, and stage 1 hypertension. During her five-day hospitalization, her condition improved. …”
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Rehabilitative Treatment as an Alternative in Amputee Patients. Case Report and Literature Review by Ismaray Sacerio González, Elohilda de la Caridad Cruz Jiménez, Silvia Georgina de la Torre Castellanos

“…The case of a 52-year-old male patient is presented, with a history of type 2 diabetes mellitus and arterial hypertension controlled by treatment, in addition to suffering from hereditary thrombopathy treated with anticoagulants, which is why he underwent surgical treatment. …”
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Virtual Screening as a Technique for PPAR Modulator Discovery by Stephanie N. Lewis, Josep Bassaganya-Riera, David R. Bevan

“…It is well recognized that PPARγ agonists have therapeutic applications as insulin sensitizers in type 2 diabetes or as anti-inflammatories. VS is a cost- and time-effective means for identifying small molecules that have therapeutic potential. …”
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Impact of digital health interventions on glycemic control and weight management by Arvind Veluvali, Ashkan Dehghani Zahedani, Amir Hosseinian, Nima Aghaeepour, Tracey McLaughlin, Mark Woodward, Alex DiTullio, Noosheen Hashemi, Michael P. Snyder

“…Abstract This retrospective cohort study evaluates the impact of an AI-supported continuous glucose monitoring (CGM) mobile app (“January V2”) on glycemic control and weight management in 944 users, including healthy individuals and those with prediabetes or type 2 diabetes (T2D). The app, leveraging AI to personalize feedback, tracked users’ food intake, activity, and glucose responses over 14 days. …”
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JAK inhibitors: a new choice for diabetes mellitus? by Mengjun Zhou, Qi Shen, Bo Li

“…Recently, several clinical cases involving the reversal of type 1 diabetes mellitus (T1DM) during treatment with JAK inhibitors have been reported, and clinical studies have described the improvement of type 2 diabetes mellitus (T2DM) during treatment with JAK inhibitors. …”
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Diagnosis of a Morgagni-Stewart-Morel Syndrome in a Patient with Ischemic Stroke. Report of a Case by Masleidy Valladares Valle, Juan Ibrahim García Leonard, Ada Sánchez Lozano

“…The case of a 77-year-old patient with a history of type 2 diabetes mellitus, systemic arterial hypertension and psychiatric disorder, who was admitted to the Neurology Service of the Dr. …”
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Spatiotemporal Regulators for Insulin-Stimulated GLUT4 Vesicle Exocytosis by Xiaoxu Zhou, Ping Shentu, Yingke Xu

“…Importantly, the dysfunction of insulin-regulated GLUT4 trafficking is strongly linked with peripheral insulin resistance and type 2 diabetes in human. The insulin signaling pathway, key signaling molecules involved, and precise trafficking itinerary of GSVs are largely identified. …”
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Ozone therapy as support in the treatment of diabetic foot ulcer. A case report by Isidro Matos Lamote, Jorge Enrique Rodríguez León, Carlos García Arencibia, Maydelin Pérez Reina

“…The case of a 43-years-old patient with a diagnosis of type 2 diabetes mellitus, of seven years of evolution, referred from the Emergency Department of the Dr. …”
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Metformin: A Possible Option in Cancer Chemotherapy by Chidiebere V. Ugwueze, Odunze J. Ogamba, Ekenechukwu E. Young, Belonwu M. Onyenekwe, Basil C. Ezeokpo

“…Metformin has been used for a long time as an antidiabetic medication for type 2 diabetes. It is used either as a monotherapy or in combination with other antidiabetic medications. …”
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Physical Activity and Arterial Stiffness: A Narrative Review by Jinyu Yang, Xiaoqian Chen, Xiang Chen, Lihua Li

“…These benefits are especially significant in populations with higher cardiovascular risk, such as those with type 2 diabetes mellitus and hypertension. Therefore, maintaining an active lifestyle into older age is crucial for vascular health and may contribute to healthy aging.…”
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