Post Varicella Necrotising Fasciitis Afflicting Upper Limb in Young Child: A Rare Case Report by Swarup Prabhu, Ayjaz Hussain, Tarun Gupta

“…Risk factors include immunosuppression, type 2 diabetes mellitus, chronic diseases like cirrhosis of liver and chronic kidney disease, malignancies, intravenous drug use, obesity, and age more than 60 years. …”
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Antenatal Corticosteroids: A Risk Factor for the Development of Chronic Disease by Elizabeth Asztalos

“…However, exogenous ACS reduces birth weight which, in turn, is associated with adverse adult outcomes such as coronary heart disease, stroke, hypertension, and type 2 diabetes. The long-term effects of ACS exposure on HPA axis activity and neurological function are well documented in animal studies, and it appears that ACS, regardless of dose exposure, is capable of affecting fetal HPA axis development causing permanent changes in the HPA axis that persists through life and is manifested by chronic illness and behavioral changes. …”
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Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols by Qi Ge, Liang Chen, Keping Chen

“…Additionally, certain polyphenols found in spices might improve glucose homeostasis and insulin resistance in diabetes patients, thereby constituting promising options for the treatment of type 2 diabetes.…”
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Exercise as a Mean to Control Low-Grade Systemic Inflammation by Neha Mathur, Bente Klarlund Pedersen

“…Chronic noncommunicable diseases (CNCDs), which include cardiovascular disease, some cancers, for example, colon cancer, breast cancer, and type 2 diabetes, are reaching epidemic proportions worldwide. …”
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The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP by Mimi Gao, Roland Winter

“…Type 2 diabetes mellitus (T2DM) is an age-related and metabolic disease. …”
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Mediation model with a categorical exposure and a censored mediator with application to a genetic study. by Jian Wang, Jing Ning, Sanjay Shete

“…We assessed the empirical performance of the proposed overall measures via simulation studies and applied the measures to evaluate the mediating effect of a women's age at menopause on the association between genetic variants and type 2 diabetes.…”
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The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes by M. C. Thomas, K. A. Jandeleit-Dahm, C. Tikellis

“…Pharmaceutical agonists of peroxisome proliferator-activated receptors (PPARs) are widely used in the management of type 2 diabetes, chiefly as lipid-lowering agents and oral hypoglycaemic agents. …”
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Autophagy-lysosome pathway in insulin & glucagon homeostasis by Yi Wu, Yi Wu, Yi Wu, Hui Wang, Huoyan Xu

“…Glucose homeostasis relies on tightly regulated insulin secretion by pancreatic β cells, and their dysfunction is a hallmark of type 2 diabetes. Glucagon also plays an important role in hyperglycemia in diabetic patients. …”
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Comprehensive management application of sulodexide on proteinuria: 2 case reports by Li Zhou, Wenge Li

“…Case 1 is a 45 years-old male with type 2 diabetes mellitus and hypertension accompanied by persistent proteinuria and intermittent edema in both legs. …”
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Role of Heme Oxygenase in Inflammation, Insulin-Signalling, Diabetes and Obesity by Joseph Fomusi Ndisang

“…A common denominator of these chronic conditions is the enhanced the levels of cytokines like tumour necrosis factor-alpha (TNF-α), interleukin (IL-6), IL-1β and resistin, which in turn activates the c-Jun-N-terminal kinase (JNK) and NF-κB pathways, creating a vicious cycle that exacerbates insulin resistance, type-2 diabetes and related complications. Emerging evidence indicates that heme oxygenase (HO) inducers are endowed with potent anti-diabetic and insulin sensitizing effects besides their ability to suppress immune/inflammatory response. …”
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Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability by Fabrizio Montecucco, Sabine Steffens, François Mach

“…This condition characterizes several diseases, such as type 2 diabetes, impaired glucose tolerance (IGT), impaired fasting glucose (IFG), obesity, hypertension, dyslipidemia, and other endocrinopathies, but also cancer. …”
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Novel Genes Potentially Involved in Fibroblasts of Diabetic Wound by Weirong Zhu, Qin Fang, Zhao Liu, Qiming Chen

“…Furthermore, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways involved in type 2 diabetes were retrieved from miRWalk. Consequently, the integrated bioinformatic analyses revealed the shared KEGG pathways between DEG-identified and diabetes-related pathways were functionally enriched in the MAPK signaling pathway, and the MAPKAPK3, HSPA2, TGFBR1, and p53 signaling pathways were involved. …”
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Metformin in the treatment of colorectal cancer and neuroendocrine tumours by Karolina Daniłowska, Natalia Picheta, Barbara I. Krupska, Anna Rudzińska, Oliwia Burdan, Katarzyna Szklener

“…Metformin, a drug commonly used in the treatment of type 2 diabetes, has demonstrated its ability to reduce the incidence and increase the efficacy of chemotherapy in colorectal cancer and neuroendocrine tumors. …”
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Current treatment landscape for obesity in Singapore by Phong Ching Lee, Chin Hong Lim, Ravishankar Asokkumar, Marvin Wei Jie Chua

“…The rising prevalence of obesity in Singapore is a harbinger for a corresponding increase in obesity-related complications such as type 2 diabetes mellitus (T2DM) and coronary heart disease. …”
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Cytokines in the Progression of Pancreatic β-Cell Dysfunction by Chunjiong Wang, Youfei Guan, Jichun Yang

“…The dysfunction of pancreatic β-cell and the reduction in β-cell mass are the decisive events in the progression of type 2 diabetes. There is increasing evidence that cytokines play important roles in the procedure of β-cell failure. …”
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Corn phytochemicals and their health benefits by Sheng Siyuan, Li Tong, RuiHai Liu

“…Keywords: Corn, Maize, Whole grains, Phytochemicals, Cardiovascular disease, Resistant starch, Type II diabetes, Diet and chronic diseases…”
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The hypoglycemic potential of phenolics from functional foods and their mechanisms by Oksana Golovinskaia, Chin-Kun Wang

“…Long-term postprandial hyperglycemia is a primary risk factor for developing chronic metabolic diseases such as obesity, type 2 diabetes, and cardiovascular disease. Chronic hyperglycemia induces the glycation of proteins, oxidative stress, inflammation and increases plasma insulin and lipid concentrations. …”
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Sleeve Gastrectomy and Gastroesophageal Reflux Disease by Michael Laffin, Johnny Chau, Richdeep S. Gill, Daniel W. Birch, Shahzeer Karmali

“…Although laparoscopic sleeve gastrectomy has been shown to be effective in producing weight loss and improving type 2 diabetes mellitus, its effect on gastroesophageal reflux disease (GERD) has been inconsistent. …”
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The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy by Samir S. Deeb, John D. Brunzell

“…Subjects with a family history of type 2 diabetes mellitus (T2DM) were more common among those who gained excessive weight. …”
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Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials by Vittorio Unfer, John E. Nestler, Zdravko A. Kamenov, Nikos Prapas, Fabio Facchinetti

“…Indeed, PCOS is the most common cause of anovulatory infertility in industrialized nations, and it is associated with insulin resistance, type 2 diabetes mellitus, and increased cardiovascular risk. …”
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